scholarly journals Ouabain-induced alterations in ABCB1 of mesenteric lymph nodes and thymocytes of rats and mice

2016 ◽  
Vol 12 (6) ◽  
pp. 5275-5280
Author(s):  
Daniel Boff Lima ◽  
Raphael Carmo Valente ◽  
Marcia Alves Marques Capella
Keyword(s):  
Lymph Nodes ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph ◽  
Rats And Mice

Inability of human clinical strains of Helicobacter pylori to colonize the alimentary tract of germfree rodents

1990 ◽  
Vol 36 (4) ◽  
pp. 237-241 ◽  
Author(s):  
Margherita T. Cantorna ◽  
Edward Balish
Keyword(s):  
Helicobacter Pylori ◽  
Lymph Nodes ◽  
Alimentary Tract ◽  
Sprague Dawley ◽  
Mesenteric Lymph Nodes ◽  
Immunodeficient Mice ◽  
Mesenteric Lymph ◽  
H Pylori ◽  
Rats And Mice ◽  
Culture Negative

Several attempts were made to colonize the alimentary tract and infect germfree BALB/c mice and germfree Sprague-Dawley rats with two human isolates of Helicobacter pylori. The alimentary tracts of mice, sacrificed at intervals between 1 day and 20 weeks after oral challenge, were culture negative for H. pylori. The alimentary tract, kidney, liver, and mesenteric lymph nodes were culture negative for H. pylori 5 h after intravenous challenge. Growth of H. pylori was inhibited by homogenates of murine stomach, small intestine, liver, and mesenteric lymph nodes. Germfree rats and mice do not appear to be readily colonized or infected by human strains of H. pylori. Key words: Helicobacter pylori, germfree mice, congenitally immunodeficient mice.

Presence of IgA-producing cells in rats and mice in relation to microbial status

1984 ◽  
Vol 18 (3) ◽  
pp. 252-257 ◽  
Author(s):  
J. W. M. A. Mullink ◽  
F. H. M. Morsink
Keyword(s):  
Lymph Nodes ◽  
Intestinal Mucosa ◽  
Mesenteric Lymph Nodes ◽  
Germ Free ◽  
Mesenteric Lymph ◽  
Significant Difference ◽  
Rats And Mice ◽  
Microbial Status

The numbers of IgA-producing cells in intestinal mucosa, mesenteric lymph nodes, lungs and bronchial lymph nodes were scored in rats and mice. A statistically significant difference in the scores existed between germ-free and SPF mice and between gnotobiotic and SPF rats. In a group of SPF rats a statistically significant difference in the scores was demonstrated in relation to several bacterial and viral agents.

In situ demonstration of migration of dendritic cells released from rat small intestine to mesenteric lymph nodes

2001 ◽  
Vol 120 (5) ◽  
pp. A183-A183
Author(s):  
H KOBAYASHI ◽  
H NAGATA ◽  
S MIURA ◽  
T AZUMA ◽  
H SUZUKI ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Small Intestine ◽  
Lymph Nodes ◽  
Rat Small Intestine ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph

scholarly journals The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes

2021 ◽  
Author(s):  
Carolin Wiechers ◽  
Mangge Zou ◽  
Eric Galvez ◽  
Michael Beckstette ◽  
Maria Ebel ◽  
...  
Keyword(s):  
T Cell ◽  
Lymph Nodes ◽  
Regulatory T Cell ◽  
De Novo ◽  
Bacterial Species ◽  
Short Chain Fatty Acids ◽  
Mesenteric Lymph Nodes ◽  
Direct Role ◽  
Early Stages ◽  
Mesenteric Lymph

AbstractIntestinal Foxp3+ regulatory T cell (Treg) subsets are crucial players in tolerance to microbiota-derived and food-borne antigens, and compelling evidence suggests that the intestinal microbiota modulates their generation, functional specialization, and maintenance. Selected bacterial species and microbiota-derived metabolites, such as short-chain fatty acids (SCFAs), have been reported to promote Treg homeostasis in the intestinal lamina propria. Furthermore, gut-draining mesenteric lymph nodes (mLNs) are particularly efficient sites for the generation of peripherally induced Tregs (pTregs). Despite this knowledge, the direct role of the microbiota and their metabolites in the early stages of pTreg induction within mLNs is not fully elucidated. Here, using an adoptive transfer-based pTreg induction system, we demonstrate that neither transfer of a dysbiotic microbiota nor dietary SCFA supplementation modulated the pTreg induction capacity of mLNs. Even mice housed under germ-free (GF) conditions displayed equivalent pTreg induction within mLNs. Further molecular characterization of these de novo induced pTregs from mLNs by dissection of their transcriptomes and accessible chromatin regions revealed that the microbiota indeed has a limited impact and does not contribute to the initialization of the Treg-specific epigenetic landscape. Overall, our data suggest that the microbiota is dispensable for the early stages of pTreg induction within mLNs.

Pericolic mesenteric lymph nodes: an aid in distinguishing diverticulitis from cancer of the colon.

1997 ◽  
Vol 169 (5) ◽  
pp. 1253-1255 ◽  
Author(s):  
K N Chintapalli ◽  
C C Esola ◽  
S Chopra ◽  
A A Ghiatas ◽  
G D Dodd
Keyword(s):  
Lymph Nodes ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph

Mesenteric lymph nodes in children: what is normal?

2005 ◽  
Vol 35 (8) ◽  
pp. 774-777 ◽  
Author(s):  
Boaz Karmazyn ◽  
Elizabeth A. Werner ◽  
Babak Rejaie ◽  
Kimberly E. Applegate
Keyword(s):  
Lymph Nodes ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph
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