scholarly journals Clinicopathological features and prognostic implications of Raf kinase inhibitor protein downregulation in tongue squamous cell carcinoma

2015 ◽  
Vol 10 (3) ◽  
pp. 1303-1308 ◽  
Author(s):  
FENGCHUN HU ◽  
XIAOHUA CHEN ◽  
XIQIANG LIU ◽  
CHENG WANG ◽  
LANHAI LV ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Kinase Inhibitor ◽  
Clinicopathological Features ◽  
Tongue Squamous Cell Carcinoma ◽  
Inhibitor Protein ◽  
Raf Kinase ◽  
Raf Kinase Inhibitor Protein ◽  
Prognostic Implications

Prognostic implications of CD44, NANOG, OCT4, and BMI1 expression in tongue squamous cell carcinoma

Head & Neck ◽  
2018 ◽  
Author(s):  
Maria Fernanda Setúbal Destro Rodrigues ◽  
Flávia Caló de Aquino Xavier ◽  
Nathália Paiva Andrade ◽  
Camila Lopes ◽  
Lucyene Miguita Luiz ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Bmi1 Expression ◽  
Prognostic Implications

scholarly journals NIT2 overexpression predicts poor prognosis in tongue squamous cell carcinoma patients

2020 ◽  
Vol 47 (3) ◽  
pp. 1553-1561
Author(s):  
Shan Chen ◽  
Zengyan Wang ◽  
Chongjin Feng
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Disease Free Survival ◽  
Clinicopathological Characteristics ◽  
Clinicopathological Features ◽  
Tongue Squamous Cell Carcinoma ◽  
Chi Square ◽  
N Classification ◽  
Disease Free Survival Rate

AbstractThere is disputable on the role of nitrilase-like 2 (NIT2) in cancer. Its expression and its relationship with clinicopathological features in tongue squamous cell carcinoma (TSCC) are not yet clear. The purpose of this study is to investigate the expression of NIT2 in TSCC and its correlation with clinicopathological characteristics in TSCC patients. Through proteomic identification, we found that the protein NIT2 was related to the development of TSCC. q-PCR, western blot and immunohistochemistry techniques were applied to detect the expression of NIT2 in TSCC. The relationship between the expression of NIT2 and clinicopathological features was analyzed by Chi square tests. The results showed the expression of NIT2 in TSCC was significantly higher than that in normal tongue tissues (p < 0.05). Univariate and multivariate analysis showed that the positive expression of NIT2 and N classification were associated with decreased disease-free survival rate (DFS) and overall survival (OS) (p < 0.05). The results suggested that NIT2 is overexpressed in TSCC and NIT2 may be a potential therapeutic target for TSCC.

Clinicopathological Features in Prognosis of Oral Tongue Squamous Cell Carcinoma

2014 ◽  
Vol 117 (2) ◽  
pp. e201
Author(s):  
PRISCILA CAMPIONI RODRIGUES ◽  
ELIZABETE BAGORDAKIS ◽  
MARCIA MIGUEL ◽  
MARCIO AJUDARTE LOPES ◽  
TUULA SALO ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinicopathological Features ◽  
Tongue Squamous Cell Carcinoma ◽  
Oral Tongue

scholarly journals Prognostic Implications of MicoRNA miR-195 Expression in Human Tongue Squamous Cell Carcinoma

PLoS ONE ◽  
2013 ◽  
Vol 8 (2) ◽  
pp. e56634 ◽  
Author(s):  
Ling-fei Jia ◽  
Su-bi Wei ◽  
Kai Gong ◽  
Ye-hua Gan ◽  
Guang-yan Yu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Human Tongue ◽  
Prognostic Implications
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