scholarly journals Occurrence of HHIP gene CpG island methylation in gastric cancer

2014 ◽  
Vol 8 (5) ◽  
pp. 2340-2344 ◽  
Author(s):  
YU SONG ◽  
YUN ZUO
Keyword(s):  
Gastric Cancer ◽  
Cpg Island ◽  
Cpg Island Methylation

scholarly journals Association between Helicobacter pylori infection and interleukin 1  polymorphism predispose to CpG island methylation in gastric cancer

Gut ◽  
2007 ◽  
Vol 56 (4) ◽  
pp. 595-597 ◽  
Author(s):  
A. O. O. Chan ◽  
K.-M. Chu ◽  
C. Huang ◽  
K. F. Lam ◽  
S. Y. Leung ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Cpg Island ◽  
Interleukin 1 ◽  
Helicobacter Pylori Infection ◽  
Cpg Island Methylation

Association Between Cyclin D1 Polymorphism with CpG Island Promoter Methylation Status of Tumor Suppressor Genes in Gastric Cancer

2010 ◽  
Vol 55 (12) ◽  
pp. 3449-3457 ◽  
Author(s):  
Tomomitsu Tahara ◽  
Tomoyuki Shibata ◽  
Masakatsu Nakamura ◽  
Hiromi Yamashita ◽  
Daisuke Yoshioka ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Tumor Suppressor ◽  
Cyclin D1 ◽  
Promoter Methylation ◽  
Tumor Suppressor Genes ◽  
Cpg Island ◽  
Methylation Status ◽  
Suppressor Genes ◽  
Promoter Methylation Status

Protective Effects of Dendrobium nobile Lindl. Alkaloids on Alzheimer's Disease-like Symptoms Induced by High-methionine Diet

2021 ◽  
Vol 19 ◽  
Author(s):  
Tingting Pi ◽  
Guangping Lang ◽  
Bo Liu ◽  
Jingshan Shi
Keyword(s):  
Alzheimer’S Disease ◽  
Learning And Memory ◽  
Morris Water Maze ◽  
Water Maze ◽  
Cpg Island ◽  
Morris Water Maze Test ◽  
Dendrobium Nobile ◽  
Maze Test ◽  
Neuron Damage ◽  
Cpg Island Methylation

Background: High methionine-diet (HMD) causes Alzheimer's disease (AD)-like symptoms. Previous studies have shown that Dendrobium nobile Lindle. alkaloids (DNLA) had potential benefits for AD. Object: Whether DNLA can improve AD-like symptoms induced by HMD is to be explored. Method: Mice were fed with 2% HMD diet for 11 weeks, the DNLA20 control group (20 mg/kg), DNLA10 group (10 mg/kg), and DNLA20 group (20 mg/kg) were administrated with DNLA for 3 months. Morris water maze test was used to detect learning and memory ability. Neuron damage was evaluated by HE and Nissl stainings. Levels of homocysteine (Hcy), beta-amyloid 1-42 (Aβ1-42), S-adenosine methionine (SAM), and S-adenosine homocysteine (SAH) were detected by ELISA. Immunofluorescence and western blotting (WB) were used to determine the expression of proteins. CPG island methylation. Results: Morris water maze test revealed that DNLA improved learning and memory dysfunction. HE, Nissl, and immunofluorescence stainings showed that DNLA alleviated neuron damage and reduced the 5-methylcytosine (5-mC), Aβ1-40, and Aβ1-42 levels. DNLA also decreased the levels of Hcy and Aβ1-42 in the serum, along with decreased SAM/SAH levels in the liver tissue. WB results showed that DNLA down-regulated the expression of the amyloid-precursor protein (APP), presenilin-1 (PS1), beta-secretase-1 (BACE1), DNA methyltransferase1 (DNMT1), Aβ1-40, and Aβ1-42 proteins. DNLA also up-regulated the expression of the protein of insulin-degrading enzyme (IDE), neprilysin (NEP), DNMT3a, and DNMT3b. Meanwhile, DNLA increased CPG island methylation levels of APP and BACE1 genes. Conclusions: DNLA alleviated AD-like symptoms induced by HMD via the DNA methylation pathway.

Aberrant CpG Island Methylation of Multiple Genes in Ependymal Tumors

2004 ◽  
Vol 67 (1/2) ◽  
pp. 159-165 ◽  
Author(s):  
M. Eva Alonso ◽  
M. Josefa Bello ◽  
Pilar Gonzalez-Gomez ◽  
Dolores Arjona ◽  
Jose M. de Campos ◽  
...  
Keyword(s):  
Cpg Island ◽  
Multiple Genes ◽  
Cpg Island Methylation

scholarly journals CpG island methylation profile in non-invasive oral rinse samples is predictive of oral and pharyngeal carcinoma

2015 ◽  
Vol 7 (1) ◽  
Author(s):  
Scott M. Langevin ◽  
Melissa Eliot ◽  
Rondi A. Butler ◽  
Agnes Cheong ◽  
Xiang Zhang ◽  
...  
Keyword(s):  
Cpg Island ◽  
Methylation Profile ◽  
Oral Rinse ◽  
Non Invasive ◽  
Pharyngeal Carcinoma ◽  
Cpg Island Methylation

scholarly journals Profile analysis and prediction of tissue-specific CpG island methylation classes

2009 ◽  
Vol 10 (1) ◽  
pp. 116 ◽  
Author(s):  
Christopher Previti ◽  
Oscar Harari ◽  
Igor Zwir ◽  
Coral del Val
Keyword(s):  
Cpg Island ◽  
Profile Analysis ◽  
Tissue Specific ◽  
Cpg Island Methylation
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