scholarly journals Association of interleukin-10 promoter polymorphisms and corresponding plasma levels with susceptibility to laryngeal squamous cell carcinoma

2014 ◽  
Vol 7 (5) ◽  
pp. 1721-1727 ◽  
Author(s):  
JIAN ZHOU ◽  
DUO ZHANG ◽  
BIN CHEN ◽  
QING LI ◽  
LIN ZHOU ◽  
...  
2003 ◽  
Vol 120 (1) ◽  
pp. 99-103 ◽  
Author(s):  
Eric Alamartine ◽  
Patricia Berthoux ◽  
Christophe Mariat ◽  
François Berthoux ◽  
Frédéric Cambazard

PLoS ONE ◽  
2017 ◽  
Vol 12 (2) ◽  
pp. e0171116 ◽  
Author(s):  
Jian Zhou ◽  
Yue Yang ◽  
Duo Zhang ◽  
Liang Zhou ◽  
Lei Tao ◽  
...  

2017 ◽  
Vol 131 (5) ◽  
pp. 455-461 ◽  
Author(s):  
J Sotirović ◽  
A Perić ◽  
D Vojvodić ◽  
N Baletić ◽  
I Zaletel ◽  
...  

AbstractObjectives:This study aimed to evaluate serum cytokine concentrations in healthy individuals and laryngeal squamous cell carcinoma patients.Methods:A total of 59 laryngeal squamous cell carcinoma patients and 44 healthy controls were included. Multiplex analysis of interleukins 2, 4, 5, 6, 10, 12, 13 and 17 and interferon-gamma with respect to the presence of laryngeal carcinoma, tumour–node–metastasis T stage, nodal involvement and larynx subsite was performed.Results:Statistical analysis revealed no difference in serum cytokine levels between patients and healthy controls. The serum interleukin-12 concentration was significantly higher in patients with early (T1–2) than in those with late (T3–4) stage disease and without nodal involvement (p < 0.05). Serum interleukin-10 levels were significantly higher in T3–4 stage than in T1–2 stage patients (p < 0.05). Additionally, serum interleukin 10, 12 and 13 concentrations (p < 0.05) and interleukin-6 concentration (p < 0.01) were significantly higher in patients with T1–2 stage supraglottic vs glottic tumours.Conclusion:Serum cytokines level cannot be used as laryngeal squamous cell carcinoma markers. Progression from T1–2 to T3–4 stage is followed by decreased serum interleukin-12 levels and increased interleukin-10 levels. Nodal involvement is associated with lower serum interleukin-12 levels. In patients with early stage tumours, serum interleukin 6, 10, 12 and 13 concentrations are significantly higher in those with supraglottic vs glottic tumours.


2021 ◽  
Vol 18 (1) ◽  
pp. 53-65
Author(s):  
AGNE PASVENSKAITE ◽  
RASA LIUTKEVICIENE ◽  
GRETA GEDVILAITE ◽  
ALVITA VILKEVICIUTE ◽  
VYKINTAS LIUTKEVICIUS ◽  
...  

2015 ◽  
Vol 22 (3) ◽  
pp. 704-713 ◽  
Author(s):  
Maria Vassilakopoulou ◽  
Margaritis Avgeris ◽  
Vamsidhar Velcheti ◽  
Vassiliki Kotoula ◽  
Theodore Rampias ◽  
...  

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