scholarly journals Fluorine-18-labeled boronophenylalanine positron emission tomography for oral cancers: Qualitative and quantitative analyses of malignant tumors and normal structures in oral and maxillofacial regions

2011 ◽  
Vol 2 (3) ◽  
pp. 423-427 ◽  
Author(s):  
YASUNORI ARIYOSHI ◽  
MASASHI SHIMAHARA ◽  
YOSHIHIRO KIMURA ◽  
YUICHI ITO ◽  
TAKESHI SHIMAHARA ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Malignant Tumors ◽  
Emission Tomography ◽  
Qualitative And Quantitative ◽  
Oral Cancers ◽  
Positron Emission ◽  
Quantitative Analyses ◽  
Oral And Maxillofacial Regions

scholarly journals Comparative Oncology: Evaluation of 2-Deoxy-2-[18F]fluoro-D-glucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) for the Staging of Dogs with Malignant Tumors

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0127800 ◽  
Author(s):  
Stefanie M. F. Seiler ◽  
Christine Baumgartner ◽  
Johannes Hirschberger ◽  
Ambros J. Beer ◽  
Andreas Brühschwein ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Malignant Tumors ◽  
Emission Tomography ◽  
Comparative Oncology ◽  
Positron Emission ◽  
Pet Ct

2-(18F)-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography Detects Clinical Relevant Adenomas of the Colon: A Prospective Study

2005 ◽  
Vol 23 (16) ◽  
pp. 3713-3717 ◽  
Author(s):  
Mariëtte C.A. van Kouwen ◽  
Fokko M. Nagengast ◽  
Jan B.M.J. Jansen ◽  
Wim J.G. Oyen ◽  
Joost P.H. Drenth
Keyword(s):  
Positron Emission Tomography ◽  
Fdg Pet ◽  
Malignant Tumors ◽  
Case Series ◽  
Emission Tomography ◽  
Low Grade ◽  
Colonic Adenomas ◽  
Positron Emission ◽  
A Prospective Study ◽  
Fdg Accumulation

Purpose 2-(18F)-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) is a noninvasive imaging technique used clinically to detect malignant tumors. FDG-PET has been established as a tool for diagnosis of recurrent or metastatic colorectal carcinoma. Several case series suggest that FDG-PET also detects larger adenomas. The goal of this study was to investigate whether FDG-PET is able to detect colonic adenomas. Patients and Methods FDG-PET was performed in 100 consecutive patients in whom colonic adenomas were suspected on barium enema (n = 47) or sigmoidoscopy (n = 53). A positive scan was defined as focal large bowel FDG accumulation. FDG-PET was followed in all cases by colonoscopy, and removed adenomas were examined histopathologically. Results Colonoscopy confirmed the presence of adenomas in 68 of 100 patients. In 35 patients, there was focal FDG accumulation at site of the adenoma. The sensitivity of FDG-PET increased with adenoma size (21%, adenomas 1 to 5 mm; 47%, 6 to 10 mm; and 72%, > 11 mm). The sensitivity of FDG-PET also increased with the grade of dysplasia (33%, low grade; 76%, high grade; and 89%, carcinomas). The overall specificity was 84%. Conclusion FDG-PET detects colonic adenomas and the diagnostic test characteristics improve with size and grade of dysplasia of the adenoma.

scholarly journals Nodal tuberculosis on positron emission tomography/computed tomography with 18F-Fluordexosiglucose, a case report

ANALES RANM ◽  
2021 ◽  
Vol 138 (138(02)) ◽  
pp. 183-185
Author(s):  
M.K. Meneses Navas ◽  
P. Romero Fernández ◽  
M.N. Cabrera Martín ◽  
A. Ortega Candil ◽  
J.L. Carreras Delgado
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Differential Diagnosis ◽  
Lymph Node ◽  
Malignant Tumors ◽  
Emission Tomography ◽  
Axial Tomography ◽  
Positron Emission ◽  
Lymph Node Tuberculosis ◽  
Granulomatous Diseases

Tuberculosis is an infectious disease, caused by the Mycobacterium tuberculosis bacillus. Extrapulmonary disease can cause nonspecific symptoms and signs, which makes diagnostic suspicion difficult. We present the case of a man with a history of cancer in complete remission, diagnosed with lymph node tuberculosis, after being admitted to our hospital due to fever, dyspnea, and central chest pain. A Positron Emission Tomography / Computed Axial Tomography with 18F-fluordexosiglucose is requested; which showed multiple mediastinal adenopathic conglomerates with intense radiotracer uptake, suggesting ruling out malignancy. Active lymph node tuberculosis will show increased metabolic activity with Positron Emission Tomography / Computed Tomography with 18F-fluordexosiglucose, which could make the differential diagnosis with malignant tumors or other granulomatous diseases difficult, as in the case of our patient. Therefore, it is important to consider lymph node tuberculosis as a differential diagnosis in patients with adenopathies suspected of malignancy.

scholarly journals Primitive neuroectodermal tumor of the pericardium: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jingjing Wang ◽  
Jing Li ◽  
Xiao Zhang ◽  
Xiaobo Zhang ◽  
Yueyong Xiao
Keyword(s):  
Positron Emission Tomography ◽  
Primitive Neuroectodermal Tumor ◽  
Malignant Tumors ◽  
Neuroectodermal Tumor ◽  
Emission Tomography ◽  
Sympathetic Nervous Systems ◽  
Positron Emission ◽  
Parietal Pericardium ◽  
Facial Edema ◽  
Spherical Mass

Abstract Background The primitive neuroectodermal tumors (PNETs) are a family of highly malignant tumors with a multidirectional differential potential. The tumors are characterized by aggressive small round tumor cells that originate from the spinal cord of the central and sympathetic nervous systems. Cases involving the pericardium are extremely rare. Herein, we present a case of peripheral primitive neuroectodermal tumor (pPNET) that originated in the pericardium. Case presentation A 23-year-old woman presented with cough and progressive dyspnea for 1 month, followed by eyelid and facial edema for 10 days, without any apparent cause. Significantly elevated tumor markers were detected in her blood. A cardiac ultrasound revealed a 74 mm × 61 mm spherical mass that was attached to the left pericardium, as well as massive pericardial effusion. Positron emission tomography-CT (PET-CT) showed focal hypermetabolism in the left pericardium. Via histopathology and immunohistochemistry, the spherical mass was identified as PNETS. The patient was successfully treated with a combination of surgical resection via thoracotomy and postoperative chemotherapy, and she was disease-free for 7 years at follow-up. Unfortunately, at 7 years after the treatment, the patient’s pPNET recurred. Positron emission tomography-MRI (PET-MRI) and 64-slice coronary CTA revealed that the aorta and multiple coronary arteries were involved. Subsequently, the patient refused a heart transplant and voluntarily left the hospital. Conclusions This paper reports on a rare and recurrent case of PNET in the parietal pericardium. With respect to the different biologic characteristics and prognoses of pPNETs (compared to other known pericardium tumors), it is essential to consider this entity as a differential diagnosis in pericardium tumors.

scholarly journals Benefits and Limitations of Multimodality Imaging in the Diagnosis of a Primary Cardiac Lymphoma

2014 ◽  
Vol 41 (6) ◽  
pp. 657-659 ◽  
Author(s):  
Prabhjot Singh Nijjar ◽  
Sofia Carolina Masri ◽  
Ashenafi Tamene ◽  
Helina Kassahun ◽  
Kenneth Liao ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Malignant Tumors ◽  
Emission Tomography ◽  
Cardiac Tumors ◽  
Imaging Methods ◽  
Positron Emission ◽  
Multiple Imaging ◽  
Primary Cardiac Tumors

Primary cardiac tumors are far rarer than tumors metastatic to the heart. Angiosarcoma is the primary cardiac neoplasm most frequently detected; lymphomas constitute only 1% of primary cardiac tumors. We present the case of a 55-year-old woman with a recently diagnosed intracardiac mass who was referred to our institution for consideration of urgent orthotopic heart transplantation. Initial images suggested an angiosarcoma; however, a biopsy specimen of the mass was diagnostic for diffuse large B-cell lymphoma. The patient underwent chemotherapy rather than surgery, and she was asymptomatic 34 months later. We use our patient's case to discuss the benefits and limitations of multiple imaging methods in the evaluation of cardiac masses. Certain features revealed by computed tomography, cardiac magnetic resonance, and positron emission tomography can suggest a diagnosis of angiosarcoma rather than lymphoma. Cardiac magnetic resonance and positron emission tomography enable reliable distinction between benign and malignant tumors; however, the characteristics of different malignant tumors can overlap. Despite the great usefulness of multiple imaging methods for timely diagnosis, defining the extent of spread and the hemodynamic impact, and monitoring responses to treatment, we think that biopsy analysis is still warranted in order to obtain a correct histologic diagnosis in cases of suspected malignant cardiac tumors.

scholarly journals [18F]ML-10 Imaging for Assessment of Apoptosis Response of Intracranial Tumor Early after Radiosurgery by PET/CT

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Lu Sun ◽  
Kedi Zhou ◽  
Weijun Wang ◽  
Xiaojun Zhang ◽  
Zhongjian Ju ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Pet Imaging ◽  
Malignant Tumors ◽  
Human Subjects ◽  
Intracranial Tumor ◽  
Emission Tomography ◽  
Positron Emission ◽  
Pet Ct ◽  
Before And After ◽  
Mri Scans

[18F]ML-10 is a novel apoptosis radiotracer for positron emission tomography (PET). We assess the apoptosis response of intracranial tumor early after CyberKnife (CK) treatment by [18F]ML-10 PET imaging. 29 human subjects (30 lesions), diagnosed with intracranial tumors, underwent CK treatment at 14–24 Gy in 1–3 fractions, had [18F]ML-10 positron emission tomography/computed tomography (PET/CT) before (pre-CK) and 48 hours after (post-CK) CK treatment. Magnetic resonance imaging (MRI) scans were taken before and 8 weeks after CK treatment. Voxel-based analysis was used for the imaging analysis. Heterogeneous changes of apoptosis in tumors before and after treatment were observed on voxel-based analysis of PET images. A positive correlation was observed between the change in radioactivity (X) and subsequent tumor volume (Y) (r=0.862, p<0.05), with a regression equation of Y=1.018∗X−0.016. Malignant tumors tend to be more sensitive to CK treatment, but the treatment outcome is not affected by pre-CK apoptotic status of tumor cells; [18F]ML-10 PET imaging could be taken as an assessment 48 h after CK treatment.

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