scholarly journals Autologous adipose tissue-derived mesenchymal stem cells are involved in rat liver regeneration following repeat partial hepatectomy

2016 ◽  
Vol 13 (3) ◽  
pp. 2053-2059 ◽  
Author(s):  
TAO LIU ◽  
HONG MU ◽  
ZHONGYANG SHEN ◽  
ZHUOLUN SONG ◽  
XIAOBO CHEN ◽  
...  
2017 ◽  
Vol 2017 ◽  
pp. 1-22 ◽  
Author(s):  
Ioannis G. Papanikolaou ◽  
Charalambos Katselis ◽  
Konstantinos Apostolou ◽  
Themistoklis Feretis ◽  
Maria Lymperi ◽  
...  

Mesenchymal stem cells (MSCs) are an attractive source for regenerative medicine because they are easily accessible through minimally invasive methods and have the potential to enhance liver regeneration (LG) and improve liver function, following partial hepatectomy (PH) and acute or chronic liver injury. A systematic review of the literature was conducted for articles published up to September 1st, 2016, using the MEDLINE database. The keywords that were used in various combinations were as follows: “Mesenchymal stem cells”, “transplantation”, “stem cells”, “adipose tissue derived stem cells”, “bone marrow-derived stem cells”, “partial hepatectomy”, “acute liver failure”, “chronic liver failure”, “liver fibrosis”, “liver cirrhosis”, “rats”, “mice”, and “liver regeneration”. All introduced keywords were searched for separately in MeSH Database to control relevance and terminological accuracy and validity. A total of 41 articles were identified for potential inclusion and reviewed in detail. After a strict selection process, a total of 28 articles were excluded, leaving 13 articles to form the basis of this systematic review. MSCs transplantation promoted LG and improved liver function. Furthermore, MSCs had the ability to differentiate in hepatocyte-like cells, increase survival, and protect hepatocytes by paracrine mechanisms. MSCs transplantation may provide beneficial effects in the process of LG after PH and acute or chronic liver injury. They may represent a new therapeutic option to treat posthepatectomy acute liver failure.


1995 ◽  
Vol 108 (4) ◽  
pp. A1186
Author(s):  
S. Theocharis ◽  
A. Margeli ◽  
N. Goutas ◽  
S. Skaltsas ◽  
A. Skopelitou ◽  
...  

2010 ◽  
Vol 52 ◽  
pp. S360-S361
Author(s):  
R.E. Castro ◽  
X. Zhang ◽  
D.M. Ferreira ◽  
P.M. Borralho ◽  
A.L. Sarver ◽  
...  

Hepatology ◽  
1997 ◽  
Vol 26 (3) ◽  
pp. 573-578 ◽  
Author(s):  
C Gerlach ◽  
D Y Sakkab ◽  
T Scholzen ◽  
R Daßler ◽  
M R Alison ◽  
...  

Hepatology ◽  
1995 ◽  
Vol 22 (5) ◽  
pp. 1584-1590 ◽  
Author(s):  
Shinichi Kiso ◽  
Sumio Kawata ◽  
Shinji Tamura ◽  
Shigeki Higashiyama ◽  
Nobuyuki Ito ◽  
...  

2007 ◽  
Vol 46 ◽  
pp. S142-S143 ◽  
Author(s):  
E. Mendieta-Condado ◽  
V. Chagoya de Sanchez ◽  
R. Hernandez-Munoz

2007 ◽  
Vol 52 (10) ◽  
pp. 2610-2615 ◽  
Author(s):  
Orlando Castro e Silva ◽  
Rafael Kemp ◽  
Ajith Kumar Sankarankutty ◽  
Sergio Zucoloto ◽  
Maria Eliza Jordani Souza ◽  
...  

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