scholarly journals Assessment of the beneficial loci and prognostic implications of microsatellite instability in gastric carcinoma

2011 ◽  
Author(s):  
Sun Hoe Koo
Keyword(s):  
Gastric Carcinoma ◽  
Microsatellite Instability ◽  
Prognostic Implications

MICROSATELLITE INSTABILITY IN INTESTINAL- AND DIFFUSE-TYPE GASTRIC CARCINOMA

1997 ◽  
Vol 182 (2) ◽  
pp. 167-173 ◽  
Author(s):  
GIOVANNI BUONSANTI ◽  
DANIELE CALISTRI ◽  
LAURA PADOVAN ◽  
OMBRETTA LUINETTI ◽  
ROBERTO FIOCCA ◽  
...  
Keyword(s):  
Gastric Carcinoma ◽  
Microsatellite Instability ◽  
Diffuse Type

scholarly journals Correlation between gastric carcinoma and ZAC gene-associated microsatellite instability and loss of heterozygosity

2017 ◽  
Vol 14 (2) ◽  
pp. 2422-2426
Author(s):  
Xiao-Yan Zhu ◽  
Ji-Yao Yang ◽  
Ying He ◽  
Guo-Hong Liu ◽  
Yun Sun ◽  
...  
Keyword(s):  
Gastric Carcinoma ◽  
Microsatellite Instability ◽  
Loss Of Heterozygosity

Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma

2001 ◽  
Vol 32 (2) ◽  
pp. 136-143 ◽  
Author(s):  
Valdemar Máximo ◽  
Paula Soares ◽  
Raquel Seruca ◽  
Ana Sofia Rocha ◽  
Patrícia Castro ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Gastric Carcinoma ◽  
Microsatellite Instability ◽  
Mitochondrial Dna Mutations ◽  
Large Deletions ◽  
Dna Mutations

Microsatellite instability and mutation of mitochondrial and nuclear DNA in gastric carcinoma

2000 ◽  
Vol 118 (5) ◽  
pp. 835-841 ◽  
Author(s):  
Wataru Habano ◽  
Tamotsu Sugai ◽  
Shin–Ichi Nakamura ◽  
Noriyuki Uesugi ◽  
Toru Yoshida ◽  
...  
Keyword(s):  
Gastric Carcinoma ◽  
Microsatellite Instability ◽  
Nuclear Dna

scholarly journals Clinicopathological Features and Prognostic Implication of Gastric Carcinoma with Lymphoid Stroma

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Jung-Soo Pyo ◽  
Nae Yu Kim ◽  
Byoung Kwan Son ◽  
Hyo Young Lee ◽  
Il Hwan Oh ◽  
...  
Keyword(s):  
Gastric Carcinoma ◽  
Meta Analysis ◽  
Survival Rates ◽  
Medullary Carcinoma ◽  
Tumor Location ◽  
Lymphatic Invasion ◽  
Clinicopathologic Characteristics ◽  
Lymphoid Stroma ◽  
Significant Difference ◽  
Prognostic Implications

Background/Objective. Gastric carcinoma with lymphoid stroma (GCLS) has been referred to as lymphoepithelioma-like carcinoma and medullary carcinoma. The present study aims at elucidating the clinicopathologic features and prognostic implications of GCLS through a meta-analysis. Methods. This study included 34 eligible studies and 1757 GCLSs. The clinicopathologic characteristics of GCLS were investigated from eligible studies, and the meta-analysis was performed. In addition, we compared the survival rates between GCLS and non-GCLS. Results. The estimated rate of GCLS was 0.062 (95% confidence interval (CI) 0.040-0.097). GCLS was significantly correlated with the diffuse type of Lauren’s classification, proximal tumor location, less-frequent lymphatic invasion, and lower pTNM stage. However, there was no significant difference in age, sex, tumor differentiation, vascular invasion, perineural invasion, pT stage, lymph node metastasis, and distant metastasis between GCLS and non-GCLS patients. EBV positive rates in GCLS and non-GCLS patients were 0.723 (95% CI 0.643-0.791) and 0.064 (95% CI 0.039-0.103), respectively. HER2 expression in GCLS was significantly lower than that in non-GCLS. GCLS patients had a more favorable prognosis than that of non-GCLS patients (hazard ratio 0.500, 95% CI 0.305-0.821). Conclusion. GCLS comprised 6.2% of overall GC and more frequent in the proximal portion of the stomach. Since GCLS was associated with better prognosis, the histologic finding can be useful for predicting the patient’s prognosis.

scholarly journals The role of microsatellite instability in gastric carcinoma

Gut ◽  
1998 ◽  
Vol 42 (2) ◽  
pp. 300-303 ◽  
Author(s):  
J D HAYDEN ◽  
I G MARTIN ◽  
L CAWKWELL ◽  
P QUIRKE
Keyword(s):  
Gastric Carcinoma ◽  
Microsatellite Instability
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