scholarly journals Clinical features and outcomes of primary bone and soft tissue sarcomas in adolescents and young adults

2020 ◽  
Author(s):  
Kazuhiko Hashimoto ◽  
Shunji Nishimura ◽  
Naohiro Oka ◽  
Masao Akagi
Keyword(s):  
Young Adults ◽  
Soft Tissue ◽  
Clinical Features ◽  
Soft Tissue Sarcomas ◽  
Adolescents And Young Adults ◽  
Primary Bone

scholarly journals Primary intracranial soft tissue sarcomas in children, adolescents, and young adults: single institution experience and review of the literature

2015 ◽  
Vol 127 (1) ◽  
pp. 155-163 ◽  
Author(s):  
Ossama M. Maher ◽  
Soumen Khatua ◽  
Devashis Mukherjee ◽  
Adriana Olar ◽  
Alexander Lazar ◽  
...  
Keyword(s):  
Young Adults ◽  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Adolescents And Young Adults ◽  
Review Of The Literature ◽  
Single Institution

The challenge of the management of adolescents and young adults with soft tissue sarcomas

2018 ◽  
Vol 65 (7) ◽  
pp. e27013 ◽  
Author(s):  
Andrea Ferrari ◽  
Archie Bleyer ◽  
Shreyaskumar Patel ◽  
Stefano Chiaravalli ◽  
Patrizia Gasparini ◽  
...  
Keyword(s):  
Young Adults ◽  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Adolescents And Young Adults

scholarly journals Long-Term Neurotoxicity of Chemotherapy in Adolescents and Young Adults Treated for Bone and Soft Tissue Sarcomas

Sarcoma ◽  
1998 ◽  
Vol 2 (2) ◽  
pp. 97-105 ◽  
Author(s):  
Helena M. Earl ◽  
Sean Connolly ◽  
Christos Latoufis ◽  
Karen Eagle ◽  
Catherine M. Ash ◽  
...  
Keyword(s):  
Young Adults ◽  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Adolescents And Young Adults

scholarly journals Insurance impacts survival for children, adolescents, and young adults with bone and soft tissue sarcomas

2019 ◽  
Vol 9 (3) ◽  
pp. 951-958 ◽  
Author(s):  
Neela L. Penumarthy ◽  
Robert E. Goldsby ◽  
Stephen C. Shiboski ◽  
Rosanna Wustrack ◽  
Patricia Murphy ◽  
...  
Keyword(s):  
Young Adults ◽  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Adolescents And Young Adults

scholarly journals Metastatic Soft Tissue Sarcomas in Adolescents and Young Adults: A Specialist Center Experience

2020 ◽  
Vol 9 (6) ◽  
pp. 628-638
Author(s):  
Eugenie Younger ◽  
Olga Husson ◽  
Bernice Asare ◽  
Charlotte Benson ◽  
Ian Judson ◽  
...  
Keyword(s):  
Young Adults ◽  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Adolescents And Young Adults ◽  
Specialist Center

Soft tissue sarcomas in adolescents and young adults: a comparison with their paediatric and adult counterparts

2017 ◽  
Vol 18 (3) ◽  
pp. e166-e175 ◽  
Author(s):  
Winette T A van der Graaf ◽  
Daniel Orbach ◽  
Ian R Judson ◽  
Andrea Ferrari
Keyword(s):  
Young Adults ◽  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Adolescents And Young Adults

Improved Survival of Children, Adolescents, and Young Adults With Head and Neck Soft Tissue Sarcomas in Denmark

2019 ◽  
pp. 1
Author(s):  
Christian Mirian ◽  
Christian Grønhøj ◽  
Catherine Rechnitzer ◽  
Birgitte Charabi ◽  
Lisa L. Hjalgrim ◽  
...  
Keyword(s):  
Young Adults ◽  
Soft Tissue ◽  
Head And Neck ◽  
Soft Tissue Sarcomas ◽  
Adolescents And Young Adults

scholarly journals DNA methylation patterns–based subtype distinction and identification of soft tissue sarcoma prognosis

2020 ◽  
Author(s):  
Zhengyuan Wu ◽  
Miao Yu ◽  
Jing-yuan Fan ◽  
Zhen-pei Wen ◽  
Tian-yu Ren ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Soft Tissue ◽  
Clinical Features ◽  
Soft Tissue Sarcomas ◽  
Survival Prediction ◽  
Biological Functions ◽  
Promoter Regions ◽  
Patient Prognosis ◽  
Selection Operator ◽  
Methylation Patterns

Abstract Background: Soft tissue sarcomas (STSs) are heterogeneous at the clinical with a variable tendency of aggressive behavior. Methods: In this study, we constructed a specific DNA methylation-based classification to identify the distinct prognosis-subtypes of STSs based on the DNA methylation spectrum from the TCGA database.Results: Eventually, samples were clustered into four subgroups, and their survival curves were distinct from each other. Meanwhile, the samples in each subgroup reflected differentially in several clinical features. Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis was also conducted on the genes of the corresponding promoter regions of the above‐described specific methylation sites, revealing that these genes were mainly concentrated in certain cancer‑associated biological functions and pathways. In addition, we calculated the differences among clustered methylation sites and performed the specific methylation sites with LASSO algorithm. The selection operator algorithm was employed to derive a risk signature model, and a prognostic signature based on these methylation sites performed well for risk stratification in STSs patients. At last, a nomogram consisted of clinical features and risk score was developed for the survival prediction. Conclusion: In conclusion, this study declares that DNA methylation-based STSs subtype classification is highly relevant for future development of personalized therapy as it identifies the prediction value of patient prognosis.

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