scholarly journals Detection of circulating tumor cells in patients with lung cancer using metallic micro‑cavity array filter: A pilot study

2020 ◽  
Author(s):  
Hideo Ichimura ◽  
Takeshi Nawa ◽  
Yusuke Yamamoto ◽  
Kei Shimizu ◽  
Keisuke Kobayashi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Pilot Study ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Micro Cavity ◽  
Cavity Array

scholarly journals Circulating tumor cells as marker of poor prognosis in metastatic lung cancer: a pilot study

2018 ◽  
Vol 38 (1) ◽  
Author(s):  
Mônica Taiane de Macêdo Diaz ◽  
Emne Ali Abdallah ◽  
Milena Shizue Tariki ◽  
Alexcia Camila Braun ◽  
Aldo Lourenço Abbade Dettino ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Pilot Study ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Poor Prognosis ◽  
Metastatic Lung Cancer ◽  
Metastatic Lung

scholarly journals A pilot study of cdc6 as a biomarker for circulating tumor cells in patients with lung cancer

2020 ◽  
Vol 34 (6) ◽  
Author(s):  
Cheng An ◽  
Guijian Liu ◽  
Shi Cheng ◽  
Bo Pang ◽  
Shipeng Sun ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Pilot Study ◽  
Tumor Cells ◽  
Circulating Tumor Cells

scholarly journals A Multicenter Pilot Study Examining the Role of Circulating Tumor Cells as a Blood-Based Tumor Marker in Patients with Extensive Small-Cell Lung Cancer

2014 ◽  
Vol 4 ◽  
Author(s):  
Chao H. Huang ◽  
Jo A. Wick ◽  
Gurusingham Sitta Sittampalam ◽  
Victor Sanjit Nirmalanandhan ◽  
Apar Kishor Ganti ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Pilot Study ◽  
Small Cell Lung Cancer ◽  
Tumor Marker ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung

scholarly journals FlowCell-enriched circulating tumor cells as a predictor of lung cancer metastasis

Human Cell ◽  
2021 ◽  
Author(s):  
Yan Lu ◽  
Yushuang Zheng ◽  
Yuhong Wang ◽  
Dongmei Gu ◽  
Jun Zhang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Cancer Metastasis ◽  
Lung Tumor ◽  
Early Stage ◽  
High Rate ◽  
Early Stage Lung Cancer ◽  
Lung Cancer Metastasis ◽  
Number Of Patients

AbstractLung cancer is the most fetal malignancy due to the high rate of metastasis and recurrence after treatment. A considerable number of patients with early-stage lung cancer relapse due to overlooked distant metastasis. Circulating tumor cells (CTCs) are tumor cells in blood circulation that originated from primary or metastatic sites, and it has been shown that CTCs are critical for metastasis and prognosis in various type of cancers. Here, we employed novel method to capture, isolate and classify CTC with FlowCell system and analyzed the CTCs from a cohort of 302 individuals. Our results illustrated that FlowCell-enriched CTCs effectively differentiated benign and malignant lung tumor and the total CTC counts increased as the tumor developed. More importantly, we showed that CTCs displayed superior sensitivity and specificity to predict lung cancer metastasis in comparison to conventional circulating biomarkers. Taken together, our data suggested CTCs can be used to assist the diagnosis of lung cancer as well as predict lung cancer metastasis. These findings provide an alternative means to screen early-stage metastasis.

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