scholarly journals Prognostic factors in patients with skeletal-related events at non-small-cell lung cancer diagnosis

2017 ◽  
Vol 7 (5) ◽  
pp. 897-902 ◽  
Author(s):  
Hiroyuki Tominaga ◽  
Takao Setoguchi ◽  
Hirofumi Shimada ◽  
Satoshi Nagano ◽  
Hiromi Sasaki ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Prognostic Factors ◽  
Small Cell Lung Cancer ◽  
Cancer Diagnosis ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Lung Cancer Diagnosis ◽  
Skeletal Related Events

scholarly journals Relationship Between Deficits in Overall Quality of Life and Non–Small-Cell Lung Cancer Survival

2012 ◽  
Vol 30 (13) ◽  
pp. 1498-1504 ◽  
Author(s):  
Jeff A. Sloan ◽  
Xinghua Zhao ◽  
Paul J. Novotny ◽  
Jason Wampfler ◽  
Yolanda Garces ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cancer Diagnosis ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Single Item ◽  
Lung Cancer Diagnosis

Purpose Evidence has suggested a clinically meaningful relationship between self-reported quality of life (QOL) of a patient with cancer at the time of receiving a cancer diagnosis and overall survival (OS). This study evaluated the prognostic value of QOL assessments with regard to OS in a large cohort of patients with lung cancer. Patients and Methods A total of 2,442 patients with non–small-cell lung cancer were observed between 1997 and 2007 and completed a single-item measure of overall QOL within the first 6 months of receiving a lung cancer diagnosis; these were dichotomized using an a priori definition of a clinically deficient score (CDS; ≤ 50 v > 50). Kaplan-Meier estimates and Cox models were used to evaluate the prognostic importance of QOL on OS alone and in the presence of covariates. Logistic regression modeling was used to identify which clinical and patient characteristics were related to a clinically meaningful deficit in QOL. Results QOL deficits at time of lung cancer diagnosis were significantly associated with OS (hazard ratio [HR], 1.55; P < .001), as were performance status, older age, smoking history, male sex, treatment factors, and stage of disease. The median survival for patients with CDS QOL was 1.6 years versus 5.6 years for patients with non-CDS QOL. After controlling for all these covariates, the indication of a clinically deficient baseline QOL still contributed significantly to the prediction of patient survival (HR, 0.67; P < .001). Conclusion Overall QOL measured by a simple single item at the time of lung cancer diagnosis is a significant and independent prognostic factor for survival in patients with lung cancer.

Prognostic Factors and Skeletal-Related Events in Patients with Small Cell Lung Cancer with Bone Metastases at the Time of Diagnosis

Oncology ◽  
2016 ◽  
Vol 90 (2) ◽  
pp. 103-111 ◽  
Author(s):  
Eun Joo Kang ◽  
Suk Young Lee ◽  
Hong Jun Kim ◽  
Kyung Hoon Min ◽  
Gyu Young Hur ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Prognostic Factors ◽  
Small Cell Lung Cancer ◽  
Bone Metastases ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Skeletal Related Events

scholarly journals miRNA Detection for non-small cell lung cancer diagnosis

2021 ◽  
Author(s):  
Carla Cruz ◽  
André Rico ◽  
Fani Sousa ◽  
Bernardo Teixeira ◽  
Daniela Alexandre
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cancer Diagnosis ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Lung Cancer Diagnosis ◽  
Mirna Detection
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