scholarly journals Long non-coding RNAs and hepatocellular carcinoma

2014 ◽  
Vol 3 (1) ◽  
pp. 13-17 ◽  
Author(s):  
FU-JUN YU ◽  
JIAN-JIAN ZHENG ◽  
PEI-HONG DONG ◽  
XIAO-MING FAN
Keyword(s):  
Hepatocellular Carcinoma ◽  
Non Coding Rnas

Long non‐coding RNAs (CASC2 and TUG1) in hepatocellular carcinoma: Clinical significance

2019 ◽  
Vol 21 (9) ◽  
Author(s):  
Noha S. Refai ◽  
Manal L. Louka ◽  
Hany Y. Halim ◽  
Iman Montasser
Keyword(s):  
Hepatocellular Carcinoma ◽  
Clinical Significance ◽  
Non Coding Rnas

scholarly journals Long Non-Coding RNAs: Potential Biomarkers and Targets for Hepatocellular Carcinoma Therapy and Diagnosis

2021 ◽  
Vol 17 (1) ◽  
pp. 220-235
Author(s):  
Donghong Yuan ◽  
Yu Chen ◽  
Xiaobing Li ◽  
Jing Li ◽  
Yueshui Zhao ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Non Coding Rnas ◽  
Therapy And Diagnosis ◽  
Potential Biomarkers

scholarly journals Landscape of associations between long non‐coding RNAs and infiltrating immune cells in liver hepatocellular carcinoma

2020 ◽  
Vol 24 (19) ◽  
pp. 11243-11253 ◽  
Author(s):  
Li Li ◽  
Xiaowei Song ◽  
Yanju Lv ◽  
Qiuying Jiang ◽  
Chengjuan Fan ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Immune Cells ◽  
Non Coding Rnas ◽  
Liver Hepatocellular Carcinoma

scholarly journals Modulation of the TGF-β signaling pathway by long noncoding RNA in hepatocellular carcinoma

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Mengzhen Han ◽  
Zhibin Liao ◽  
Furong Liu ◽  
Xiaoping Chen ◽  
Bixiang Zhang
Keyword(s):  
Hepatocellular Carcinoma ◽  
Growth Factor ◽  
Noncoding Rna ◽  
Poor Prognosis ◽  
Therapeutic Strategy ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Cellular Processes ◽  
Therapy Targets ◽  
Non Coding Rnas

AbstractHepatocellular carcinoma (HCC) is a type of liver cancer with poor prognosis. There have been demonstrated to exist many possible mechanisms in HCC tumorigenesis, and recent investigations have provided some promising therapy targets. However, further mechanisms remain to be researched to improve the therapeutic strategy and diagnosis of HCC. Transforming growth factor-β (TGF-β) is a pleiotropic cytokine which plays critical roles in networks of different cellular processes, and TGF-β signaling has been found to participate in tumor initiation and development of HCC in recent years. Moreover, among the molecules and signaling pathways, researchers paid more attention to lncRNAs (long non-coding RNAs), but the connection between lncRNAs and TGF-βremain poorly understood. In this review, we conclude the malignant procedure which lncRNAs and TGF-β involved in, and summarize the mechanisms of lncRNAs and TGF-βin HCC initiation and development. Furthermore, the interaction between lncRNA and TGF-β are paid more attention, and the potential therapy targets are mentioned.

Transcriptomic profiling of long non-coding RNAs in non-virus associated hepatocellular carcinoma

2020 ◽  
Vol 78 (4) ◽  
pp. 465-474
Author(s):  
Lu Liu ◽  
Chen He ◽  
Haosheng Liu ◽  
Ganlu Wang ◽  
Zhiwu Lv ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Transcriptomic Profiling ◽  
Non Coding Rnas
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