Prevalence of human papillomavirus type 16-related DNA in cutaneous Bowen's disease and squamous cell cancer

Author(s):  
A Rubben ◽  
J Baron ◽  
E GrussendorfConen
2021 ◽  
Vol 2 (1) ◽  
pp. 01-04
Author(s):  
I. Mbarki Mbarki

Bowen’s disease, also known as intraepithelial neoplasia, is a very slow-growing carcinoma in situ. It can progress to an invasive squamous cell cancer and infiltrate mucosa or skin in 3 to 5% of cases. The anal localization of this disease is very rare. Surgical resection is the standard of treatment. Radiotherapy keeps its place in recurrent or unresectable cases. We report a case of Bowen’s anal canal disease in order to verify the effectiveness of Radiotherapy. He is a 59-years-old patient diagnosed with Bowen’s anal canal disease at the National Institute of Oncology in Rabat. He was treated with exclusive radiotherapy at a dose of 60 Gray in 30 fractions over 49 days. The evolution was marked by a complete clinical and radiological response and preservation of the anal sphincter with an 18 months follow-up.


Oncotarget ◽  
2017 ◽  
Vol 8 (49) ◽  
pp. 86369-86383 ◽  
Author(s):  
Nene N. Kalu ◽  
Tuhina Mazumdar ◽  
Shaohua Peng ◽  
Li Shen ◽  
Vaishnavi Sambandam ◽  
...  

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