Histone deacetylase inhibitor reverses multidrug resistance by attenuating the nucleophosmin level through PI3K/Akt pathway in breast cancer

SI-YING CHEN; XIAO-WEI ZHENG; JIANG-XIA CAI; WEI-PENG ZHANG; HAI-SHENG YOU; JIAN-FENG XING; YA-LIN DONG

doi:10.3892/ijo.2016.3528

Histone deacetylase inhibitor reverses multidrug resistance by attenuating the nucleophosmin level through PI3K/Akt pathway in breast cancer

International Journal of Oncology ◽

10.3892/ijo.2016.3528 ◽

2016 ◽

Vol 49 (1) ◽

pp. 294-304 ◽

Cited By ~ 7

Author(s):

SI-YING CHEN ◽

XIAO-WEI ZHENG ◽

JIANG-XIA CAI ◽

WEI-PENG ZHANG ◽

HAI-SHENG YOU ◽

...

Keyword(s):

Breast Cancer ◽

Multidrug Resistance ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Akt Pathway ◽

Deacetylase Inhibitor

Download Full-text

Histone deacetylase inhibitor suberoyl bis-hydroxamic acid suppresses cell proliferation and induces apoptosis in breast cancer cells

Molecular Medicine Reports ◽

10.3892/mmr.2014.3076 ◽

2014 ◽

Vol 11 (4) ◽

pp. 2908-2912 ◽

Cited By ~ 3

Author(s):

XINMIAO YANG ◽

NING ZHANG ◽

ZELIANG SHI ◽

ZHANGYU YANG ◽

XICHUN HU

Keyword(s):

Breast Cancer ◽

Cell Proliferation ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Breast Cancer Cells ◽

Deacetylase Inhibitor

Download Full-text

The histone deacetylase inhibitor trichostatin A alters microRNA expression profiles in apoptosis-resistant breast cancer cells

Oncology Reports ◽

10.3892/or.2011.1488 ◽

2011 ◽

Cited By ~ 4

Author(s):

Bridgette Collins-Burow

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Trichostatin A ◽

Expression Profiles ◽

Microrna Expression ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin

Download Full-text

Phase I-II study of the histone deacetylase inhibitor (HDACi) vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer (MBC): New York Cancer Consortium trial P7703.

10.1158/0008-5472.sabcs-404 ◽

2009 ◽

Cited By ~ 4

Author(s):

B Ramaswamy ◽

K Bhalla ◽

B Cohen ◽

C Pellegrino ◽

D Hershman ◽

...

Keyword(s):

Breast Cancer ◽

New York ◽

Metastatic Breast Cancer ◽

Phase I ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Metastatic Breast ◽

Deacetylase Inhibitor

Download Full-text

A Phase II Study of the Histone Deacetylase Inhibitor, Vorinostat, in Combination with Trastuzumab in Patients with Advanced Metastatic and/or Local Chest Wall Recurrent HER-2 Amplified Breast Cancer Resistant to Transtuzumab-Containing Therapy: (E1104) a Trial of the Eastern Cooperative Oncology Group.

10.1158/0008-5472.sabcs-09-5084 ◽

2009 ◽

Cited By ~ 7

Author(s):

R. Swaby ◽

M. Wang ◽

J. Sparano ◽

K. Bhalla ◽

N. Meropol ◽

...

Keyword(s):

Breast Cancer ◽

Histone Deacetylase ◽

Chest Wall ◽

Phase Ii ◽

Histone Deacetylase Inhibitor ◽

Phase Ii Study ◽

Eastern Cooperative Oncology Group ◽

Oncology Group ◽

Deacetylase Inhibitor ◽

Her 2

Download Full-text

Abstract P1-07-01: Histone deacetylase inhibitor entinostat reverses epithelial to mesenchymal transition of breast cancer cells by reversing the repression of E-cadherin

10.1158/0008-5472.sabcs13-p1-07-01 ◽

2013 ◽

Author(s):

GJ Sabnis ◽

P Shah ◽

A Kazi ◽

Y Gau ◽

S Chumsri ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Epithelial To Mesenchymal Transition ◽

Mesenchymal Transition ◽

Deacetylase Inhibitor ◽

E Cadherin

Download Full-text

Abstract P6-12-14: Histone deacetylase inhibitor suberoylanilide hydroxamic acid targets breast cancer stem cells and inhibits metastasis

10.1158/0008-5472.sabcs13-p6-12-14 ◽

2013 ◽

Author(s):

K Chu ◽

TL Green ◽

KM Boley ◽

M Cristofanilli ◽

FM Robertson

Keyword(s):

Breast Cancer ◽

Stem Cells ◽

Cancer Stem Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Suberoylanilide Hydroxamic Acid ◽

Breast Cancer Stem Cells ◽

Deacetylase Inhibitor

Download Full-text

Abstract 5847: A histone deacetylase inhibitor OBP-801 and eribulin synergistically inhibit the growth with apoptosis in triple-negative breast cancer cells

10.1158/1538-7445.am2018-5847 ◽

2018 ◽

Author(s):

Hisako Ono ◽

Yoshihiro Sowa ◽

Yosuke Iizumi ◽

Mano Horinaka ◽

Tetsuya Taguchi ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Triple Negative Breast Cancer ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Triple Negative ◽

Deacetylase Inhibitor

Download Full-text

Synergistic epigenetic reactivation of estrogen receptor-alpha (ERalpha) by combined green tea polyphenol and histone deacetylase inhibitor in ERalpha-negative breast cancer cells

Molecular Cancer ◽

10.1186/1476-4598-9-274 ◽

2010 ◽

Vol 9 (1) ◽

pp. 274 ◽

Cited By ~ 115

Author(s):

Yuanyuan Li ◽

Yih-Ying Yuan ◽

Syed M. Meeran ◽

Trygve O. Tollefsbol

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Histone Deacetylase ◽

Green Tea ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Estrogen Receptor Alpha ◽

Tea Polyphenol ◽

Deacetylase Inhibitor ◽

Green Tea Polyphenol

Download Full-text

Inhibition of the proliferation of acquired aromatase inhibitor-resistant breast cancer cells by histone deacetylase inhibitor LBH589 (panobinostat)

Breast Cancer Research and Treatment ◽

10.1007/s10549-012-2332-x ◽

2012 ◽

Vol 137 (1) ◽

pp. 93-107 ◽

Cited By ~ 30

Author(s):

Makoto Kubo ◽

Noriko Kanaya ◽

Karineh Petrossian ◽

Jingjing Ye ◽

Charles Warden ◽

...

Keyword(s):

Breast Cancer ◽

Aromatase Inhibitor ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Deacetylase Inhibitor

Download Full-text

The synthetic oleanane triterpenoids and the histone deacetylase inhibitor vorinostat cooperate to delay tumor development in a transgenic model of estrogen receptor-negative breast cancer

10.1349/ddlp.355 ◽

2011 ◽

Author(s):

Kim M. Tran

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Tumor Development ◽

Transgenic Model ◽

Deacetylase Inhibitor ◽

Estrogen Receptor Negative

Download Full-text