The cyclin-dependent kinase inhibitor SNS-032 induces apoptosis in breast cancer cells via depletion of Mcl-1 and X-linked inhibitor of apoptosis protein and displays antitumor activity in vivo

GUI’E XIE; HONGPING TANG; SHAOQING WU; JINGSONG CHEN; JIANGWEN LIU; CAN LIAO

doi:10.3892/ijo.2014.2467

The cyclin-dependent kinase inhibitor SNS-032 induces apoptosis in breast cancer cells via depletion of Mcl-1 and X-linked inhibitor of apoptosis protein and displays antitumor activity in vivo

International Journal of Oncology ◽

10.3892/ijo.2014.2467 ◽

2014 ◽

Vol 45 (2) ◽

pp. 804-812 ◽

Cited By ~ 18

Author(s):

GUI’E XIE ◽

HONGPING TANG ◽

SHAOQING WU ◽

JINGSONG CHEN ◽

JIANGWEN LIU ◽

...

Keyword(s):

Breast Cancer ◽

Antitumor Activity ◽

Breast Cancer Cells ◽

Kinase Inhibitor ◽

Inhibitor Of Apoptosis ◽

Cyclin Dependent Kinase ◽

Inhibitor Of Apoptosis Protein ◽

Cyclin Dependent Kinase Inhibitor ◽

Apoptosis Protein

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X-Linked Inhibitor of Apoptosis Protein Inhibits Apoptosis in Inflammatory Breast Cancer Cells with Acquired Resistance to an ErbB1/2 Tyrosine Kinase Inhibitor

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-10-0160 ◽

2010 ◽

Vol 9 (5) ◽

pp. 1432-1442 ◽

Cited By ~ 42

Author(s):

Katherine M. Aird ◽

Rami B. Ghanayem ◽

Sharon Peplinski ◽

Herbert K. Lyerly ◽

Gayathri R. Devi

Keyword(s):

Breast Cancer ◽

Tyrosine Kinase Inhibitor ◽

Cancer Cells ◽

Inflammatory Breast Cancer ◽

Breast Cancer Cells ◽

Kinase Inhibitor ◽

Acquired Resistance ◽

Inhibitor Of Apoptosis ◽

Inhibitor Of Apoptosis Protein ◽

Apoptosis Protein

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Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells

Carcinogenesis ◽

10.1093/carcin/bgr017 ◽

2011 ◽

Vol 32 (6) ◽

pp. 812-821 ◽

Cited By ~ 32

Author(s):

Benjamin A.T. Rodriguez ◽

Yu-I Weng ◽

Ta-Ming Liu ◽

Tao Zuo ◽

Pei-Yin Hsu ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Kinase Inhibitor ◽

Cyclin Dependent Kinase ◽

Imprinted Gene ◽

Cyclin Dependent Kinase Inhibitor ◽

Epigenetic Repression

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HIV-1 Tat Peptide Immunoconjugates Differentially Sensitize Breast Cancer Cells to Selected Antiproliferative Agents That Induce the Cyclin-Dependent Kinase Inhibitor p21WAF-1/CIP-1

Bioconjugate Chemistry ◽

10.1021/bc060053r ◽

2006 ◽

Vol 17 (5) ◽

pp. 1280-1287 ◽

Cited By ~ 14

Author(s):

Meiduo Hu ◽

Judy Wang ◽

Paul Chen ◽

Raymond M. Reilly

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Kinase Inhibitor ◽

Cyclin Dependent Kinase ◽

Tat Peptide ◽

Antiproliferative Agents ◽

Cyclin Dependent Kinase Inhibitor ◽

Hiv 1

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Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway

Oncotarget ◽

10.18632/oncotarget.20227 ◽

2017 ◽

Vol 8 (45) ◽

pp. 78781-78795 ◽

Cited By ~ 5

Author(s):

Su Ji Jo ◽

Pil-Gu Park ◽

Hye-Ran Cha ◽

Sung Gwe Ahn ◽

Min Jung Kim ◽

...

Keyword(s):

Breast Cancer ◽

Breast Cancer Cells ◽

Triple Negative ◽

Epithelial Mesenchymal Transition ◽

Akt Signaling ◽

Inhibitor Of Apoptosis ◽

Akt Signaling Pathway ◽

Mesenchymal Transition ◽

Inhibitor Of Apoptosis Protein ◽

Apoptosis Protein

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Abstract 3849: The antidiabetic drug metformin increases pro-apoptotic effect of TRAIL therapy by reducing X-linked inhibitor of apoptosis protein (XIAP) levels in triple-negative breast cancer cells

10.1158/1538-7445.am2016-3849 ◽

2016 ◽

Author(s):

Elena Strekalova ◽

Dmitry Malin ◽

Vincent Cryns

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Triple Negative Breast Cancer ◽

Breast Cancer Cells ◽

Triple Negative ◽

Inhibitor Of Apoptosis ◽

Antidiabetic Drug ◽

Inhibitor Of Apoptosis Protein ◽

Apoptosis Protein ◽

Apoptotic Effect

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Antiprogestin Inhibition of Cell Cycle Progression in T-47D Breast Cancer Cells Is Accompanied by Induction of the Cyclin-Dependent Kinase Inhibitor p21

Molecular Endocrinology ◽

10.1210/mend.11.1.9869 ◽

1997 ◽

Vol 11 (1) ◽

pp. 54-66 ◽

Cited By ~ 20

Author(s):

Elizabeth A. Musgrove ◽

Christine S. L. Lee ◽

Ann L. Cornish ◽

Alex Swarbrick ◽

Robert L. Sutherland

Keyword(s):

Breast Cancer ◽

Cell Cycle ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Cell Cycle Progression ◽

Kinase Inhibitor ◽

Cyclin Dependent Kinase ◽

Cycle Progression ◽

Cyclin Dependent Kinase Inhibitor

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The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: Implications for therapy of drug resistant breast cancers

Cell Cycle ◽

10.4161/cc.8.9.8323 ◽

2009 ◽

Vol 8 (9) ◽

pp. 1421-1425 ◽

Cited By ~ 5

Author(s):

Alessandra Cappellini ◽

Francesca Chiarini ◽

Andrea Ognibene ◽

James A. McCubrey ◽

Alberto M. Martelli

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Caspase 3 ◽

Kinase Inhibitor ◽

Drug Resistant ◽

Breast Cancers ◽

Cyclin Dependent Kinase ◽

Cyclin Dependent Kinase Inhibitor ◽

P Glycoprotein

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Blockade of Rac1 Activity Induces G1 Cell Cycle Arrest or Apoptosis in Breast Cancer Cells through Downregulation of Cyclin D1, Survivin, and X-Linked Inhibitor of Apoptosis Protein

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-09-0906 ◽

2010 ◽

Vol 9 (6) ◽

pp. 1657-1668 ◽

Cited By ~ 54

Author(s):

Tatsushi Yoshida ◽

Yaqin Zhang ◽

Leslie A. Rivera Rosado ◽

Junjie Chen ◽

Tahira Khan ◽

...

Keyword(s):

Breast Cancer ◽

Cell Cycle ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Inhibitor Of Apoptosis ◽

Inhibitor Of Apoptosis Protein ◽

Cycle Arrest ◽

Rac1 Activity ◽

Apoptosis Protein ◽

G1 Cell Cycle Arrest

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Novel Polypyridyl chelators deplete cellular zinc and destabilize the X-linked inhibitor of apoptosis protein (XIAP) prior to induction of apoptosis in human prostate and breast cancer cells

Journal of Cellular Biochemistry ◽

10.1002/jcb.24132 ◽

2012 ◽

Vol 113 (8) ◽

pp. 2567-2575 ◽

Cited By ~ 17

Author(s):

Jian Zuo ◽

Sara M. Schmitt ◽

Zhen Zhang ◽

Jai Prakash ◽

Yuhua Fan ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Human Prostate ◽

Inhibitor Of Apoptosis ◽

Inhibitor Of Apoptosis Protein ◽

Apoptosis Protein ◽

Induction Of Apoptosis ◽

Cellular Zinc

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Abstract 3782: Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is mediated by downregulation of X-linked inhibitor of apoptosis protein

10.1158/1538-7445.am10-3782 ◽

2010 ◽

Author(s):

Su-Hyeong Kim ◽

Shivendra V. Singh

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Inhibitor Of Apoptosis ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Inhibitor Of Apoptosis Protein ◽

Apoptosis Protein ◽

Induced Apoptosis

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