scholarly journals Role of metallothionein 1E in the migration and invasion of human glioma cell lines

2012 ◽  
Vol 41 (4) ◽  
pp. 1305-1313 ◽  
Author(s):  
HYANG-HWA RYU ◽  
SHIN JUNG ◽  
TAE-YOUNG JUNG ◽  
KYUNG-SUB MOON ◽  
IN-YOUNG KIM ◽  
...  
Keyword(s):  
Cell Lines ◽  
Glioma Cell ◽  
Migration And Invasion ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Glioma Cell Lines

scholarly journals Long Intergenic Noncoding RNA 00152 Promotes Glioma Cell Proliferation and Invasion by Interacting with MiR-16

2018 ◽  
Vol 46 (3) ◽  
pp. 1055-1064 ◽  
Author(s):  
Xin Chen ◽  
Deheng Li ◽  
Yang Gao ◽  
Wei Tang ◽  
Lao IW ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Cell Lines ◽  
Glioma Cell ◽  
Migration And Invasion ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Glioma Cell Lines ◽  
Glioma Cell Proliferation ◽  
Proliferation And Invasion

Background/Aims: Long noncoding RNAs (lncRNAs) are a novel class of protein-noncoding transcripts that are aberrantly expressed in multiple diseases including cancers. LINC00152 has been identified as an oncogene involved in many kinds of cancer; however, its expression pattern and function in human glioma remain unclear. Methods: Quantitative real-time polymerase chain reaction was carried out to measure LINC00152 expression in human glioma cell lines and tissues. CCK-8 and EdU assays were performed to assess cell proliferation, and scratch assays and Transwell assays were used to assess cell migration and invasion, respectively. Luciferase reporter assays were carried out to determine the interaction between miR-16 and LINC00152. In vivo experiments were conducted to assess tumor formation. Results: LINC00152 was found to be significantly upregulated in human glioma cell lines and clinical samples. Knockdown of LINC00152 suppressed glioma cell proliferation, migration, and invasion in vitro. In vivo assays in nude mice confirmed that LINC00152 knockdown inhibits tumor growth. Furthermore, mechanistic investigation showed that LINC00152 binds to miR-16 in a sequence-specific manner and suppresses its expression. miR-16 inhibition strongly attenuated LINC00152 knockdown–mediated suppressive effects on proliferation, migration, and invasion. Moreover, LINC00152 induced BMI1 expression by sponging miR-16; this effect further promoted glioma cell proliferation and invasion. Conclusion: We regard LINC00152 as an oncogenic lncRNA promoting glioma cell proliferation and invasion and as a potential target for human glioma treatment.

Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation

2011 ◽  
Vol 89 (3) ◽  
pp. 303-315 ◽  
Author(s):  
Ching-Hsein Chen ◽  
Yu-Jia Chang ◽  
Maurice S. B. Ku ◽  
King-Thom Chung ◽  
Jen-Tsung Yang
Keyword(s):  
Valproic Acid ◽  
Cell Lines ◽  
Glioma Cell ◽  
Redox Regulation ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Glioma Cell Lines ◽  
Induced Apoptosis

scholarly journals Verotoxin-1 induction of apoptosis in Gb3-expressing human glioma cell lines

2006 ◽  
Vol 5 (9) ◽  
pp. 1211-1217 ◽  
Author(s):  
David Johansson ◽  
Anders Johansson ◽  
Kjell Grankvist ◽  
Ulrika Andersson ◽  
Roger Henriksson ◽  
...  
Keyword(s):  
Cell Lines ◽  
Glioma Cell ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Glioma Cell Lines ◽  
Induction Of Apoptosis

Effect of human T lymphotropic retrovirus-I exposure on cultured human glioma cell lines

1991 ◽  
Vol 81 (6) ◽  
pp. 670-674 ◽  
Author(s):  
B. Macchi ◽  
B. Caronti ◽  
M. Pezzella ◽  
E. Bonmassar ◽  
G. Lauro
Keyword(s):  
Cell Lines ◽  
Glioma Cell ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Glioma Cell Lines

Oncostatin M signaling in human glioma cell lines

2005 ◽  
Author(s):  
Annika Krona ◽  
Sofia Järnum ◽  
Leif Salford ◽  
Bengt Widegren ◽  
Pierre Åman
Keyword(s):  
Cell Lines ◽  
Glioma Cell ◽  
Oncostatin M ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Glioma Cell Lines

Correlation between Kir4.1 expression and barium-sensitive currents in rat and human glioma cell lines

2021 ◽  
Vol 741 ◽  
pp. 135481
Author(s):  
Annett Madadi ◽  
Jakob Wolfart ◽  
Falko Lange ◽  
Hannes Brehme ◽  
Michael Linnebacher ◽  
...  
Keyword(s):  
Cell Lines ◽  
Glioma Cell ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Glioma Cell Lines
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