Wild-type p53 marginally induces endogenous MDR-1 mRNA without causing a measurable drug resistance in human cancer cells

2001 ◽  
Author(s):  
Maria Nicoletti ◽  
Timothy Myers ◽  
Tito Fojo ◽  
Mikhail Blagosklonny
Keyword(s):  
Drug Resistance ◽  
Cancer Cells ◽  
Human Cancer ◽  
Wild Type ◽  
Human Cancer Cells ◽  
Wild Type P53 ◽  
Mdr 1

scholarly journals Differential involvement of the CD95 (Fas/APO-1) receptor/ligand system on apoptosis induced by the wild-type p53 gene transfer in human cancer cells

Oncogene ◽  
1999 ◽  
Vol 18 (13) ◽  
pp. 2189-2199 ◽  
Author(s):  
Takuya Fukazawa ◽  
Toshiyoshi Fujiwara ◽  
Yoshinori Morimoto ◽  
Jianghua Shao ◽  
Masahiko Nishizaki ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Cancer Cells ◽  
Human Cancer ◽  
P53 Gene ◽  
Wild Type ◽  
Receptor Ligand ◽  
Human Cancer Cells ◽  
Ligand System ◽  
Differential Involvement ◽  
Wild Type P53

scholarly journals Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53

Autophagy ◽  
2011 ◽  
Vol 7 (11) ◽  
pp. 1348-1358 ◽  
Author(s):  
Kaipeng Jing ◽  
Kyoung-Sub Song ◽  
Soyeon Shin ◽  
Nayeong Kim ◽  
Soyeon Jeong ◽  
...  
Keyword(s):  
Docosahexaenoic Acid ◽  
Cancer Cells ◽  
Human Cancer ◽  
Mtor Signaling ◽  
Wild Type ◽  
Human Cancer Cells ◽  
Wild Type P53

scholarly journals Telomere erosion triggers growth arrest but not cell death in human cancer cells retaining wild-type p53: implications for antitelomerase therapy

Oncogene ◽  
2004 ◽  
Vol 23 (23) ◽  
pp. 4136-4145 ◽  
Author(s):  
Ana Preto ◽  
Sim K Singhrao ◽  
Michele F Haughton ◽  
David Kipling ◽  
David Wynford-Thomas ◽  
...  
Keyword(s):  
Cell Death ◽  
Cancer Cells ◽  
Human Cancer ◽  
Growth Arrest ◽  
Wild Type ◽  
Human Cancer Cells ◽  
Wild Type P53 ◽  
Telomere Erosion

scholarly journals Failure of wild-type p53 gene therapy in human cancer cells expressing a mutant p53 protein

Gene Therapy ◽  
1999 ◽  
Vol 6 (1) ◽  
pp. 22-33 ◽  
Author(s):  
A Vinyals ◽  
M A Peinado ◽  
M Gonzalez-Garrigues ◽  
M Monzó ◽  
R D Bonfil ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Cancer Cells ◽  
Human Cancer ◽  
P53 Protein ◽  
P53 Gene ◽  
Mutant P53 ◽  
Wild Type ◽  
Human Cancer Cells ◽  
Wild Type P53

A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells

2011 ◽  
Vol 149 (2) ◽  
pp. 196-205 ◽  
Author(s):  
Joanna Kopecka ◽  
Ivana Campia ◽  
Paolo Olivero ◽  
Gianpiero Pescarmona ◽  
Dario Ghigo ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Cancer Cells ◽  
Liposomal Doxorubicin ◽  
Human Cancer ◽  
Human Cancer Cells
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