Suppression of the expression of hypoxia-inducible factor-1α by RNA interference alleviates hypoxia-induced pulmonary hypertension in adult rats

Ying Li; Bo Shi; Liping Huang; Xin Wang; Xiaona Yu; Baosheng Guo; Weidong Ren

doi:10.3892/ijmm.2016.2773

Suppression of the expression of hypoxia-inducible factor-1α by RNA interference alleviates hypoxia-induced pulmonary hypertension in adult rats

International Journal of Molecular Medicine ◽

10.3892/ijmm.2016.2773 ◽

2016 ◽

Vol 38 (6) ◽

pp. 1786-1794 ◽

Cited By ~ 11

Author(s):

Ying Li ◽

Bo Shi ◽

Liping Huang ◽

Xin Wang ◽

Xiaona Yu ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Rna Interference ◽

Hypoxia Inducible Factor ◽

Adult Rats ◽

Hypoxia Inducible Factor 1Α

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Apigenin Attenuates Pulmonary Hypertension by Inducing PASMCs Mitochondria-Dependent Apoptosis Via Inhibiting Hypoxia Inducible Factor 1α-KV1.5 Channel Pathway

SSRN Electronic Journal ◽

10.2139/ssrn.3444382 ◽

2019 ◽

Author(s):

Yuanzhou He ◽

Xiaoyu Fang ◽

Ying Zhou ◽

Jing Shi ◽

Xiaochen Li ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Hypoxia Inducible Factor ◽

Hypoxia Inducible Factor 1Α

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Silencing of Hypoxia Inducible Factor-1α by RNA Interference Attenuates Human Glioma Cell Growth In vivo

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-06-2692 ◽

2007 ◽

Vol 13 (8) ◽

pp. 2441-2448 ◽

Cited By ~ 74

Author(s):

David L. Gillespie ◽

Kum Whang ◽

Brian T. Ragel ◽

Jeannette R. Flynn ◽

David A. Kelly ◽

...

Keyword(s):

Rna Interference ◽

Cell Growth ◽

Glioma Cell ◽

Hypoxia Inducible Factor ◽

Human Glioma ◽

Human Glioma Cell ◽

Hypoxia Inducible Factor 1Α

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Novel Role for the Regulation of Mitochondrial Fission by Hypoxia Inducible Factor-1α in the Control of Smooth Muscle Remodeling and Progression of Pulmonary Hypertension

Circulation Research ◽

10.1161/circresaha.112.270801 ◽

2012 ◽

Vol 110 (11) ◽

pp. 1395-1397 ◽

Cited By ~ 10

Author(s):

Michael S. Wolin

Keyword(s):

Pulmonary Hypertension ◽

Smooth Muscle ◽

Mitochondrial Fission ◽

Hypoxia Inducible Factor ◽

Hypoxia Inducible Factor 1Α ◽

Muscle Remodeling

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Hypoxia-Inducible Factor-1α in Pulmonary Arterial Smooth Muscle Cells and Hypoxia-induced Pulmonary Hypertension

American Journal of Respiratory and Critical Care Medicine ◽

10.1164/rccm.201312-2148ed ◽

2014 ◽

Vol 189 (3) ◽

pp. 245-246 ◽

Cited By ~ 10

Author(s):

Kimberly A. Smith ◽

Jason X.-J. Yuan

Keyword(s):

Pulmonary Hypertension ◽

Smooth Muscle ◽

Smooth Muscle Cells ◽

Hypoxia Inducible Factor ◽

Muscle Cells ◽

Arterial Smooth Muscle ◽

Hypoxia Inducible Factor 1Α ◽

Pulmonary Arterial ◽

Arterial Smooth Muscle Cells ◽

Pulmonary Arterial Smooth Muscle

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Altered hypoxia-inducible factor-1α (HIF-1α ) signaling contributes to impaired angiogenesis in fetal lambs with persistent pulmonary hypertension of the newborn (PPHN)

Physiological Reports ◽

10.14814/phy2.13986 ◽

2019 ◽

Vol 7 (3) ◽

pp. e13986 ◽

Cited By ~ 1

Author(s):

Kartikeya Makker ◽

Adeleye J. Afolayan ◽

Ru-Jeng Teng ◽

Girija G. Konduri

Keyword(s):

Pulmonary Hypertension ◽

Hypoxia Inducible Factor ◽

Persistent Pulmonary Hypertension ◽

Hypoxia Inducible Factor 1Α ◽

Impaired Angiogenesis

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Inhibition of expression of hypoxia-inducible factor-1α mRNA by nitric oxide in hypoxic pulmonary hypertension rats

Journal of Huazhong University of Science and Technology [Medical Sciences] ◽

10.1007/bf02830693 ◽

2004 ◽

Vol 24 (1) ◽

pp. 5-8 ◽

Cited By ~ 3

Author(s):

AO Qilin ◽

Huang Lei ◽

Zhu Pengcheng ◽

Xiong Mi ◽

Wang Dixun

Keyword(s):

Nitric Oxide ◽

Pulmonary Hypertension ◽

Hypoxia Inducible Factor ◽

Hypoxic Pulmonary Hypertension ◽

Hypoxia Inducible Factor 1Α

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Chronic hypoxia- and monocrotaline-induced elevation of hypoxia-inducible factor-1α levels and pulmonary hypertension

Journal of Biomedical Science ◽

10.1007/bf02254435 ◽

2004 ◽

Vol 11 (3) ◽

pp. 315-321

Author(s):

Yih-Loong Lai ◽

Tai Chung Law

Keyword(s):

Pulmonary Hypertension ◽

Chronic Hypoxia ◽

Hypoxia Inducible Factor ◽

Hypoxia Inducible Factor 1Α

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RNA Interference Targeting Hypoxia Inducible Factor 1α Reduces Post-Operative Adhesions in Rats

Journal of Surgical Research ◽

10.1016/j.jss.2006.07.045 ◽

2007 ◽

Vol 141 (2) ◽

pp. 162-170 ◽

Cited By ~ 26

Author(s):

Tatiana Segura ◽

Hugo Schmokel ◽

Jeffrey A. Hubbell

Keyword(s):

Rna Interference ◽

Hypoxia Inducible Factor ◽

Hypoxia Inducible Factor 1Α

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Loss of smooth muscle cell hypoxia inducible factor‐1α underlies increased vascular contractility in pulmonary hypertension

The FASEB Journal ◽

10.1096/fj.201600557r ◽

2016 ◽

Vol 31 (2) ◽

pp. 650-662 ◽

Cited By ~ 16

Author(s):

Elizabeth A. Barnes ◽

Chih‐Hsin Chen ◽

Oshra Sedan ◽

David N. Cornfield

Keyword(s):

Pulmonary Hypertension ◽

Smooth Muscle ◽

Smooth Muscle Cell ◽

Muscle Cell ◽

Hypoxia Inducible Factor ◽

Vascular Contractility ◽

Hypoxia Inducible Factor 1Α ◽

Cell Hypoxia

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RNA interference-mediated downregulation of hypoxia-inducible factor-1α inhibits angiogenesis and survival of oral squamous cell carcinoma in vitro and in vivo

European Journal of Cancer Prevention ◽

10.1097/cej.0b013e32834dbbda ◽

2012 ◽

Vol 21 (3) ◽

pp. 289-299 ◽

Cited By ~ 8

Author(s):

Hao Zhou ◽

Wei Fei ◽

Yun Bai ◽

Songsong Zhu ◽

En Luo ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Rna Interference ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Hypoxia Inducible Factor ◽

Hypoxia Inducible Factor 1Α

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