scholarly journals Adenosine and the adenosine A2A receptor agonist, CGS21680, upregulate CD39 and CD73 expression through E2F-1 and CREB in regulatory T cells isolated from septic mice

2016 ◽  
Vol 38 (3) ◽  
pp. 969-975 ◽  
Author(s):  
Rui Bao ◽  
Xianqi Shui ◽  
Jiong Hou ◽  
Jinbao Li ◽  
Xiaoming Deng ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
A2a Receptor ◽  
Cd73 Expression ◽  
Adenosine A2a

scholarly journals Adenosine A2A Receptor Agonist–Mediated Increase in Donor-Derived Regulatory T Cells Suppresses Development of Graft-versus-Host Disease

2012 ◽  
Vol 190 (1) ◽  
pp. 458-468 ◽  
Author(s):  
Kyu Lee Han ◽  
Stephenie V. M. Thomas ◽  
Sherry M. Koontz ◽  
Cattlena M. Changpriroa ◽  
Seung-Kwon Ha ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Graft Versus Host Disease ◽  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
Host Disease ◽  
Graft Versus Host ◽  
A2a Receptor ◽  
Adenosine A2a

scholarly journals The Diameter of Retinal Arterioles Is Unaffected by Intravascular Administration of the Adenosine A2A Receptor Agonist Regadenoson in Normal Persons

2019 ◽  
Vol 4 (2) ◽  
pp. 1-10 ◽  
Author(s):  
Anna Dons-Jensen ◽  
Line Petersen ◽  
Hans-Erik Bøtker ◽  
Toke Bek
Keyword(s):  
Intravenous Administration ◽  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
Retinal Vessels ◽  
Adenosine Receptor Agonists ◽  
Retinal Arterioles ◽  
A2a Receptor ◽  
Adenosine A2a

Background: The neurotransmitter adenosine has been proposed to be involved in the pathogenesis of diabetic retinopathy, which may be due to the vasoactive properties of the compound. Previous studies have shown that adenosine can affect the tone of retinal arterioles in vitro to induce dilatation mediated by A2A and A2Breceptors and constriction mediated by A1 and A3 receptors. Purpose: To investigate effects of intravenous administration of the adenosine A2A receptor agonist regadenoson on the diameter of retinal vessels in vivo. Method: The diameter responses of larger retinal arterioles and venules were evaluated using the dynamic vessel analyser in 20 normal persons (age 22–31 years) after intravenous administration of the adenosine A2A receptor agonist regadenoson during exposure to systemic normoxia and hypoxia. Results: The diameter of retinal arterioles and venules increased significantly during stimulation with flickering light (p < 0.0001). Regadenoson reduced the flicker-induced dilatation of venules during normoxia (p = 0.0006), but otherwise had no effect on vessel diameters (p > 0.08 for all comparisons). Conclusions:Intravenous administration of the adenosine A2A receptor agonist regadenoson had no significant effect on the diameter of retinal arterioles. Future studies should investigate differential effects of intra- and extravascular administration of adenosine receptor agonists on retinal vessels.

Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat

2002 ◽  
Vol 438 (3) ◽  
pp. 183-188 ◽  
Author(s):  
John R Fozard ◽  
Karen M Ellis ◽  
Maria F Villela Dantas ◽  
Bruno Tigani ◽  
Lazzaro Mazzoni
Keyword(s):  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
Cgs 21680 ◽  
A2a Receptor ◽  
Adenosine A2a ◽  
Airways Inflammation

scholarly journals Corrigendum: Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells

2019 ◽  
Vol 10 ◽  
Author(s):  
Claudia Sorrentino ◽  
Fokhrul Hossain ◽  
Paulo C. Rodriguez ◽  
Rosa A. Sierra ◽  
Antonio Pannuti ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Adenosine A2a Receptor ◽  
Receptor Stimulation ◽  
A2a Receptor ◽  
Adenosine A2a

Effects of adenosine A2a receptor agonist and antagonist on hippocampal nuclear factor-kB expression preceded by MDMA toxicity

2012 ◽  
Vol 28 (1) ◽  
pp. 45-52 ◽  
Author(s):  
Fatemeh Kermanian ◽  
Mansooreh Soleimani ◽  
Alireza Ebrahimzadeh ◽  
Hossein Haghir ◽  
Mehdi Mehdizadeh
Keyword(s):  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
Nuclear Factor ◽  
A2a Receptor ◽  
Agonist And Antagonist ◽  
Adenosine A2a ◽  
Nuclear Factor Kb

ChemInform Abstract: The Synthesis and Biological Activity of a Highly Selective Adenosine A2a Receptor Agonist.

ChemInform ◽  
2010 ◽  
Vol 31 (10) ◽  
pp. no-no
Author(s):  
David R. Borcherding ◽  
Nelsen L. Lentz ◽  
Philip M. Weintraub ◽  
Mark W. Dudley ◽  
Roberta Secrest ◽  
...  
Keyword(s):  
Biological Activity ◽  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
A2a Receptor ◽  
Adenosine A2a

scholarly journals Synergistic interaction between a PDE5 inhibitor (sildenafil) and a new adenosine A2A receptor agonist (LASSBio-1359) improves pulmonary hypertension in rats

PLoS ONE ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. e0195047 ◽  
Author(s):  
Allan K. Alencar ◽  
Fábio I. Carvalho ◽  
Ananssa M. Silva ◽  
Sabrina T. Martinez ◽  
Jorge A. Calasans-Maia ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Receptor Agonist ◽  
Pde5 Inhibitor ◽  
Adenosine A2a Receptor ◽  
Synergistic Interaction ◽  
A2a Receptor ◽  
Adenosine A2a
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