scholarly journals Forced mastication increases survival of adult neural stem cells in the hippocampal dentate gyrus

2012 ◽  
Vol 31 (2) ◽  
pp. 307-314 ◽  
Author(s):  
YUKI AKAZAWA ◽  
TAKAMASA KITAMURA ◽  
YURI FUJIHARA ◽  
YOSHITAKA YOSHIMURA ◽  
MASATO MITOME ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Dentate Gyrus ◽  
Hippocampal Dentate Gyrus ◽  
Adult Neural Stem Cells

scholarly journals The Ventral Hippocampus Is the Embryonic Origin for Adult Neural Stem Cells in the Dentate Gyrus

Neuron ◽  
2013 ◽  
Vol 78 (4) ◽  
pp. 658-672 ◽  
Author(s):  
Guangnan Li ◽  
Li Fang ◽  
Gloria Fernández ◽  
Samuel J. Pleasure
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Dentate Gyrus ◽  
Ventral Hippocampus ◽  
Adult Neural Stem Cells ◽  
Embryonic Origin

scholarly journals Isolation of the side population from adult neurogenic niches enriches for endothelial cells

2021 ◽  
Author(s):  
Alena Kalinina ◽  
Yingben Xue ◽  
Catherine Gnyra ◽  
Diane Lagace
Keyword(s):  
Stem Cells ◽  
Endothelial Cells ◽  
Dna Binding ◽  
Neural Stem Cells ◽  
Dentate Gyrus ◽  
Abc Transporter ◽  
Lateral Ventricle ◽  
Side Population ◽  
Adult Brain ◽  
Adult Neural Stem Cells

In stem cell research, DNA-binding dyes offer the ability to purify live stem cells using flow cytometry as they form a low-fluorescence side population due to the activity of ABC transporters. Adult neural stem cells exist within the lateral ventricle and dentate gyrus of the adult brain yet the ability of DNA-binding dyes to identify these adult stem cells as side populations remain untested. The following experiments utilize the efflux of a DNA-binding dye, Vyrbant DyeCycle Violet (DCV), to isolate bona fide side populations in the adult mouse dentate gyrus and SVZ and test their sensitivity to ABC transporter inhibitors. A distinct side population was found in both the adult lateral ventricle and dentate gyrus using DCV fluorescence and forward scatter instead of the conventional dual fluorescence approach. These side populations responded strongly to inhibition with the ABC transporter antagonists, verapamil and fumitremorgin C. The cells in the side population were identified as cerebrovascular endothelial cells characterized by their expression of CD31. These findings, therefore, suggest that the side population analysis provides an efficient method to purify endothelial cells, but not adult neural stem cells.

scholarly journals In Vivo Targeting of Adult Neural Stem Cells in the Dentate Gyrus by a Split-Cre Approach

2014 ◽  
Vol 2 (2) ◽  
pp. 153-162 ◽  
Author(s):  
Ruth Beckervordersandforth ◽  
Aditi Deshpande ◽  
Iris Schäffner ◽  
Hagen B. Huttner ◽  
Alexandra Lepier ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Dentate Gyrus ◽  
Adult Neural Stem Cells
Sign in / Sign up

Export Citation Format

Share Document