scholarly journals Analysis and optimization of interactions between peptides mimicking the GD2 ganglioside and the monoclonal antibody 14G2a

2011 ◽  
Author(s):  
Irena Horwacik
Keyword(s):  
Monoclonal Antibody ◽  
Gd2 Ganglioside

scholarly journals Targeting and killing glioblastoma with monoclonal antibody to O-acetyl GD2 ganglioside

Oncotarget ◽  
2016 ◽  
Vol 7 (27) ◽  
pp. 41172-41185 ◽  
Author(s):  
Julien Fleurence ◽  
Denis Cochonneau ◽  
Sophie Fougeray ◽  
Lisa Oliver ◽  
Fanny Geraldo ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Gd2 Ganglioside

Targeting of small-cell lung cancer using the anti-GD2 ganglioside monoclonal antibody 3F8: A pilot trial

1996 ◽  
Vol 23 (2) ◽  
pp. 145-149 ◽  
Author(s):  
Stefan C. Grant ◽  
Lale Kostakoglu ◽  
Mark G. Kris ◽  
Samuel D. J. Yeh ◽  
Steven M. Larson ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Monoclonal Antibody ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Pilot Trial ◽  
Small Cell ◽  
Small Cell Lung ◽  
Gd2 Ganglioside

scholarly journals A Monoclonal Antibody to O-Acetyl-GD2 Ganglioside and Not to GD2 Shows Potent Anti-Tumor Activity without Peripheral Nervous System Cross-Reactivity

PLoS ONE ◽  
2011 ◽  
Vol 6 (9) ◽  
pp. e25220 ◽  
Author(s):  
Nidia Alvarez-Rueda ◽  
Ariane Desselle ◽  
Denis Cochonneau ◽  
Tanguy Chaumette ◽  
Béatrice Clemenceau ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Nervous System ◽  
Peripheral Nervous System ◽  
Cross Reactivity ◽  
Anti Tumor Activity ◽  
Gd2 Ganglioside

scholarly journals Analysis of genes involved in response to doxorubicin and a GD2 ganglioside-specific 14G2a monoclonal antibody in IMR-32 human neuroblastoma cells

2015 ◽  
Vol 62 (3) ◽  
pp. 423-433 ◽  
Author(s):  
Irena Horwacik ◽  
Małgorzata Durbas ◽  
Elżbieta Boratyn ◽  
Anna Sawicka ◽  
Paulina Węgrzyn ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Neuroblastoma Cells ◽  
Human Neuroblastoma Cells ◽  
Human Neuroblastoma ◽  
Gd2 Ganglioside

scholarly journals Anti-proliferative and pro-apoptotic activity of GD2 ganglioside-specific monoclonal antibody 3F8 in human melanoma cells

2015 ◽  
Vol 4 (8) ◽  
pp. e1023975 ◽  
Author(s):  
Chun-Yen Tsao ◽  
Francesco Sabbatino ◽  
Nai-Kong V Cheung ◽  
Jeff Chi-feng Hsu ◽  
Vincenzo Villani ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Specific Monoclonal Antibody ◽  
Human Melanoma Cells ◽  
Apoptotic Activity ◽  
Gd2 Ganglioside

A web-like network of type vi collagen in human skin is revealed by immuno-electron microscopy

1988 ◽  
Vol 46 ◽  
pp. 382-383
Author(s):  
Douglas R. Keene ◽  
Robert W. Glanville ◽  
Eva Engvall
Keyword(s):  
Electron Microscopy ◽  
Monoclonal Antibody ◽  
Human Skin ◽  
Basement Membranes ◽  
Primary Antibody ◽  
Fat Cells ◽  
Secondary Antibody ◽  
Type Vi Collagen ◽  
Dermal Matrix ◽  
Immuno Electron Microscopy

A mouse monoclonal antibody (5C6) prepared against human type VI collagen (1) has been used in this study to immunolocalize type VI collagen in human skin. The enbloc method used involves exposing whole tissue pieces to primary antibody and 5 nm gold conjugated secondary antibody before fixation, and has been described in detail elsewhere (2).Biopsies were taken from individuals ranging in age from neonate to 65 years old. By immuno-electron microscopy, type VI collagen is found to be distributed as a fine branching network closely associated with (but not attached to) banded collagen fibrils containing types I and III collagen (Fig. 1). It appears to enwrap fibers, to weave between individual fibrils within a fiber, and to span the distance separating fibers, creating a “web-like network” which entraps fibers within deep papillary and reticular dermal layers (Fig. 2). Relative to that in the dermal matrix, the concentration of type VI collagen is higher around endothelial basement membranes limiting the outer boundaries of nerves, capillaries, and fat cells (Fig. 3).

High-voltage electron microscopy of subretinal scar formation

1992 ◽  
Vol 50 (1) ◽  
pp. 486-487
Author(s):  
G.E. Korte ◽  
M. Marko ◽  
G. Hageman
Keyword(s):  
Electron Microscopy ◽  
Monoclonal Antibody ◽  
Retinal Pigment Epithelium ◽  
Glial Cells ◽  
High Voltage ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Sodium Iodate ◽  
High Voltage Electron Microscopy ◽  
Voltage Electron

Sodium iodate iv. damages the retinal pigment epithelium (RPE) in rabbits. Where RPE does not regenerate (e.g., 1,2) Muller glial cells (MC) forma subretinal scar that replaces RPE. The MC response was studied by HVEM in 3D computer reconstructions of serial thick sections, made using the STEREC0N program (3), and the HVEM at the NYS Dept. of Health in Albany, NY. Tissue was processed for HVEM or immunofluorescence localization of a monoclonal antibody recognizing MG microvilli (4).

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