scholarly journals Expression of inflammatory factors and oxidative stress markers in serum of patients with coronary heart disease and correlation with coronary artery calcium score

2020 ◽  
Author(s):  
Datong Chen ◽  
Minghui Liang ◽  
Cheng Jin ◽  
Yue Sun ◽  
Dongbin Xu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Coronary Artery Calcium Score ◽  
Calcium Score ◽  
Inflammatory Factors ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
And Oxidative Stress

scholarly journals Expression of serum inflammatory cytokines and oxidative stress markers and their correlation with coronary artery calcium score in patients with coronary heart disease

2020 ◽  
Author(s):  
Jia-Qi Yao ◽  
Zhuo-Jun Deng ◽  
Ming-Xing Fang ◽  
Na Xiao ◽  
Qing-Sheng Huang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Coronary Artery Calcium Score ◽  
Calcium Score ◽  
Observation Group ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
And Oxidative Stress

IntroductionThe present study was conducted to explore the expression of serum inflammatory cytokines and oxidative stress markers in patients with coronary heart disease (CHD), with an attempt to analyze their relationship with the coronary artery calcium score (CACS) by coronary computed tomography angiography (CCTA).Material and methodsIt total 81 patients with coronary heart disease and 81 healthy adults were included as the observation group and the control group, respectively. The levels of serum interleukin (IL)-6 and IL-12 of the two groups were detected by ELISA, and serum superoxide dismutase (SOD) was detected by the hydroxylamine oxidation method. Micro-RNA-497-5p (miR-497-5p) was screened out as a possible new CHD biomarker and its serum level was measured by real-time fluorescence quantitative PCR. The CACS of patients in the observation group was calculated by the Agatston method to analyze the correlation between the abovementioned indexes and CACS.ResultsWith increase in the number of CHD lesions, the levels of IL-6, IL-12 and miR-497-5p rose gradually while the level of SOD decreased gradually. In the observation group, IL-6, IL-12 and miR-497-5p were positively correlated with CACS while SOD was negatively correlated with CACS.ConclusionsAbnormal expression levels of serum IL-6, IL-12, SOD and miR-497-5p may be able to reveal the severity of the disease, and the combination with CACS is of potential value in terms of evaluating the condition of patients harboring coronary heart disease.

Association between novel oxidative stress markers and C-reactive protein among adults without clinical coronary heart disease

2005 ◽  
Vol 178 (1) ◽  
pp. 115-121 ◽  
Author(s):  
Jerome L. Abramson ◽  
W. Craig Hooper ◽  
Dean P. Jones ◽  
Salman Ashfaq ◽  
Steven D. Rhodes ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Oxidative Stress Markers ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Stress Markers

scholarly journals Using the Coronary Artery Calcium Score to Predict Coronary Heart Disease Events

2004 ◽  
Vol 164 (12) ◽  
pp. 1285 ◽  
Author(s):  
Mark J. Pletcher ◽  
Jeffrey A. Tice ◽  
Michael Pignone ◽  
Warren S. Browner
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Coronary Artery Calcium ◽  
Coronary Artery Calcium Score ◽  
Calcium Score
Sign in / Sign up

Export Citation Format

Share Document