scholarly journals Abnormalities of diffusional kurtosis imaging and regional homogeneity in idiopathic generalized epilepsy with generalized tonic‑clonic seizures

2018 ◽  
Author(s):  
Guohao Liu ◽  
Guiwen Lyu ◽  
Na Yang ◽  
Boyu Chen ◽  
Jian Yang ◽  
...  
Keyword(s):  
Regional Homogeneity ◽  
Idiopathic Generalized Epilepsy ◽  
Diffusional Kurtosis Imaging ◽  
Clonic Seizures ◽  
Generalized Epilepsy

scholarly journals Diffusional kurtosis imaging reveals a distinctive pattern of microstructural alternations in idiopathic generalized epilepsy

2014 ◽  
Vol 130 (3) ◽  
pp. 148-155 ◽  
Author(s):  
C.-Y. Lee ◽  
A. Tabesh ◽  
M. V. Spampinato ◽  
J. A. Helpern ◽  
J. H. Jensen ◽  
...  
Keyword(s):  
Distinctive Pattern ◽  
Idiopathic Generalized Epilepsy ◽  
Diffusional Kurtosis Imaging ◽  
Generalized Epilepsy

Lack of Evidence for Association Between D2S124 and D2S111 Polymorphisms of the SCN2A Gene and Idiopathic Generalized Epilepsy With Generalized Tonic—Clonic Seizures

2007 ◽  
Vol 22 (7) ◽  
pp. 907-910 ◽  
Author(s):  
Anna Volzone ◽  
Renata Rizzo ◽  
Antonella Gagliano ◽  
Mariella Palmarino ◽  
Paola Lucarelli ◽  
...  
Keyword(s):  
Idiopathic Generalized Epilepsy ◽  
Clonic Seizures ◽  
Generalized Epilepsy

Severe Idiopathic Generalized Epilepsy of Infancy with Generalized Tonic-Clonic Seizures

1998 ◽  
Vol 29 (05) ◽  
pp. 229-238 ◽  
Author(s):  
H. Doose ◽  
Heike Lunau ◽  
Eva Castiglione ◽  
S. Waltz
Keyword(s):  
Idiopathic Generalized Epilepsy ◽  
Clonic Seizures ◽  
Generalized Epilepsy

scholarly journals Children with idiopathic generalized epilepsy those underwent at least two years seizure remission: a retrospective analysis

2021 ◽  
Vol 8 (9) ◽  
pp. 1508
Author(s):  
Chandan Raybarman
Keyword(s):  
Antiepileptic Drugs ◽  
Idiopathic Generalized Epilepsy ◽  
Care Clinic ◽  
Female Ratio ◽  
Titration Phase ◽  
Male Female Ratio ◽  
Clonic Seizures ◽  
Generalized Epilepsy ◽  
Initial Target

Background: The aim of the retrospective study was to evaluate the effectiveness of the index antiepileptic drugs in children with idiopathic generalized epilepsy who underwent at least 2 years remission.Methods: A total of 52 children with idiopathic generalized epilepsy who underwent at least 2 years remission were identified retrospectively from the records of the paediatric and neurology care clinic from April 2017 to December 2020.Results: The seizure patterns of 52 cases were tonic-clonic seizures alone (73%), a combination of tonic-clonic seizures and absences (13.5%), and combined tonic-clonic seizures and myoclonus (13.5%).  The total number of seizures at enrolment in all (age at seizure onset 7.44±5.12 years, male-female ratio (31:21) was 651 (mean 12.52±26.60). The total number of follow-up visits in all was 6.62±14.44 consisting of 1177.5±772.86 days of follow-up periods. All patients continued index antiepileptic drugs with initial target doses varies from low to moderate ranges. Add-on therapy was initiated in 43% of cases around the titration phase of index antiepileptic drugs (i.e. very early add-on). Treatment trends reveal increased use of 1st generation antiepileptic drugs than 2nd and 3rd generation. 2 years seizure remission rates were 55.77% by index antiepileptic drugs only therapy and 44.23% by very early add-on therapy.  The seizure remission period was mean±SD 858.71±209.08 days.Conclusions: Index antiepileptic drugs with low to moderate initial target doses lead to achieving 2 years or more seizure remission. Very early add-on therapy is the novelty and leads to achieving the goal.

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