scholarly journals The relationship between insulin resistance, adiponectin and C-reactive protein and vascular endothelial injury in diabetic patients with coronary heart disease

2018 ◽  
Author(s):  
Weihua Xu ◽  
Minghui Tian ◽  
Yanju Zhou
Keyword(s):  
Insulin Resistance ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Endothelial Injury ◽  
Diabetic Patients ◽  
Vascular Endothelial ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
The Relationship

scholarly journals C-Reactive Protein and Coronary Heart Disease: All Said—Is Not It?

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Frederik Strang ◽  
Heribert Schunkert
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Experimental Studies ◽  
Epidemiological Studies ◽  
Experimental Investigations ◽  
C Reactive Protein ◽  
Genetic Studies ◽  
Reactive Protein ◽  
The Relationship

C-reactive protein (CRP) and coronary heart disease (CHD) have been the subject of intensive investigations over the last decades. Epidemiological studies have shown an association between moderately elevated CRP levels and incident CHD whereas genetic studies have shown that polymorphisms associated with elevated CRP levels do not increase the risk of ischemic vascular disease, suggesting that CRP might be a bystander rather than a causal factor in the progress of atherosclerosis. Beside all those epidemiological and genetic studies, the experimental investigations also try to reveal the role of CRP in the progress of atherosclerosis. This review will highlight the complex results of genomic, epidemiological, and experimental studies on CRP and will show why further studies investigating the relationship between CRP and atherosclerosis might be needed.

scholarly journals Factors of raised C-reactive protein as a potential determinant of Diabetic patients and Risk factor for Coronary Heart Disease

2018 ◽  
Vol 5 (3) ◽  
pp. 3656-3661
Author(s):  
Sharma Sushil Kumar ◽  
Rastogi Parag
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Type 1 Diabetes ◽  
Heart Disease ◽  
Research Work ◽  
Islet Autoimmunity ◽  
Diabetic Patients ◽  
C Reactive Protein ◽  
Reactive Protein

Elevated C-reactive protein (CRP) levels have previously been described before the onset of type 1 diabetes and gestational diabetes. We hypothesized that inflammation, as reflected by elevated CRP levels, can help predict development of islet autoimmunity or type 1 diabetes. The outcome of this research is to establish potential determinants of raised CRP concentrations in type 1 diabetic patients. Sensitive assay showed ‘low-level’ CRP concentrations in 147 type 1 patients (83M, 64F, median age 30 years, range 13–67). We have done step by step variant examination to relate these CRP levels to known cardiovascular risk factors and demographic data. Only four patients had established Coronary Heart Disease (median CRP 3.43 mg/l vs. 0.85 mg/l, p=0.035). In subjects without overt CHD, multivariate analysis revealed increase in subject age (p=0.0027), BMI (p=0.001) and HbA1 (p=0.013) to be associated with a higher CRP concentration, as was female sex (p=0.025) and a history of CHD in a first-degree relative (p=0.018, n=58). Elevated CRP levels were positively associated with cardiovascular and renal risk factors: age, body mass index, blood pressure, serum cholesterol level, smoking, plasma glucose level and elevated urinary albumin excretion and presence of hypertension were unrelated. This research work advises that certain of the risk factors connected with CHD in type 1 patients are also individually predictive of high CRP concentrations. The reasons for this, and whether intervention would prove valuable, require further analysis

Lipoprotein complexed C-reactive protein in patients with coronary heart disease

2005 ◽  
Vol 94 (11) ◽  
pp. 1111-1112 ◽  
Author(s):  
Thorsten Kälsch ◽  
Martin Borggrefe ◽  
Carl-Erik Dempfle ◽  
Elif Elmas
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Insulin Resistance and the Relationship of a Dyslipidemia to Coronary Heart Disease

2011 ◽  
Vol 31 (5) ◽  
pp. 1208-1214 ◽  
Author(s):  
Sander J. Robins ◽  
Asya Lyass ◽  
Justin P. Zachariah ◽  
Joseph M. Massaro ◽  
Ramachandran S. Vasan
Keyword(s):  
Insulin Resistance ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Relationship Of ◽  
The Relationship
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