scholarly journals Correlation between root respiration and the levels of biomass and glycyrrhizic acid in Glycyrrhiza uralensis

2017 ◽  
Vol 14 (3) ◽  
pp. 2323-2328 ◽  
Author(s):  
Wenlan Liu ◽  
Zhirong Sun ◽  
Jixu Qu ◽  
Chunning Yang ◽  
Xiaomin Zhang ◽  
...  
Keyword(s):  
Root Respiration ◽  
Glycyrrhizic Acid ◽  
Glycyrrhiza Uralensis

Ultrasound Changes Solid-Liquid Leaching Equilibrium of Glycyrrhizic Acid from Glycyrrhiza Uralensis in Water

2012 ◽  
Vol 455-456 ◽  
pp. 721-725
Author(s):  
Xiao Guang Yang ◽  
Hong Xing Dong ◽  
Guo Jun Yue ◽  
Yuan Lv ◽  
Jin Yong Tang ◽  
...  
Keyword(s):  
Glycyrrhizic Acid ◽  
Glycyrrhiza Uralensis ◽  
Solid Liquid

Effect of molybdenum on secondary metabolic process of glycyrrhizic acid in Glycyrrhiza uralensis Fisch.

2013 ◽  
Vol 50 ◽  
pp. 93-100 ◽  
Author(s):  
Dan Wang ◽  
Yu-Xin Pang ◽  
Wen-Quan Wang ◽  
Chun-Yang Wan ◽  
Jun-Ling Hou ◽  
...  
Keyword(s):  
Glycyrrhizic Acid ◽  
Metabolic Process ◽  
Glycyrrhiza Uralensis ◽  
Glycyrrhiza Uralensis Fisch

Ultrasound Changes Solid-Liquid Leaching Equilibrium of Glycyrrhizic Acid from Glycyrrhiza Uralensis in Water

2012 ◽  
Vol 455-456 ◽  
pp. 721-725
Author(s):  
Xiao Guang Yang ◽  
Hong Xing Dong ◽  
Guo Jun Yue ◽  
Yuan Lv ◽  
Jin Yong Tang ◽  
...  
Keyword(s):  
Electron Microscope ◽  
Scanning Electron Microscope ◽  
Glycyrrhizic Acid ◽  
Equilibrium Concentration ◽  
Glycyrrhiza Uralensis ◽  
Ultrasonic Frequency ◽  
Ultrasonic Power ◽  
Solid Structure ◽  
Solid Liquid ◽  
Scanning Electron

This work reported that ultrasound changed the solid-liquid leaching equilibrium of glycyrrhizic acid (GA) from glycyrrhiza uralensis in water. Several critical variables were considered, including temperature, ultrasonic power and frequency. The equilibrium concentration of GA increased by increasing the temperature, while the optimal ultrasonic frequency was affected by the temperature and the ultrasonic power affected the concentration lightly when the power was more than 100W. To investigate the cause that ultrasound changed the solid-liquid leaching equilibrium, a scanning electron microscope was used to observe the solid structure before ultrasound treatment and after that. It was found that ultrasound was able to change the structure of glycyrrhiza uralensis. So a new equilibrium was built and the equilibrium concentration of GA was influenced because the solid structure was transformed by ultrasound.

scholarly journals Effect of Glycyrrhizic Acid on Scopolamine-Induced Cognitive Impairment in Mice

2020 ◽  
Vol 24 (Suppl 1) ◽  
pp. S48-55
Author(s):  
Ju Yeon Ban ◽  
Hyun Kyung Park ◽  
Su Kang Kim
Keyword(s):  
Superoxide Dismutase ◽  
Cognitive Impairment ◽  
Glycyrrhizic Acid ◽  
Neuroprotective Effect ◽  
Acetylcholinesterase Activity ◽  
Treated Group ◽  
Glycyrrhiza Uralensis ◽  
Mice Model ◽  
Maze Test ◽  
Y Maze

Purpose: Cognitive impairment is one of the main symptoms of Alzheimer disease and other dementias. Glycyrrhiza uralensis is a natural product that has a protective effect against cognitive impairment. In this study, we investigated whether glycyrrhizic acid, among the main bioactive components of <i>Glycyrrhiza uralensis</i>, has a neuroprotective effect on scopolamine-induced cognitive impairment.Methods: Twenty-week-old male Institute of Cancer Research mice were used in this study. The scopolamine-induced cognitive impairment mice model was used. Glycyrrhizic acid was orally administered to mice once daily for 21 days, while scopolamine (1 mg/kg) treatment was delivered 30 minutes before behavioral tests. Donepezil (2 mg/kg) was used as a positive drug control. To evaluate the effect of glycyrrhizic acid, the following assessments were performed on hippocampal tissue: Y-maze test, acetylcholinesterase activity, antioxidant enzymes’ activity (superoxide dismutase, catalase). Western blotting for phosphor-extracellular signal-regulated kinase, P38, and c-Jun NH2-terminal kinase was conducted.Results: We found that glycyrrhizic acid administration significantly improved scopolamine-induced cognitive impairment in the Y-maze test. The acetylcholinesterase activity, superoxide dismutase, and catalase activity in the glycyrrhizic acid-treated group showed a significant reversal of cognitive impairment compared with the scopolamine-treated group.Conclusions: Our results suggest that glycyrrhizic acid has a neuroprotective effect on cognitive function in scopolamine-induced cognitive impairment.

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