scholarly journals Prognostic significance of the mRNA expression of ERCC1, RRM1, TUBB3 and TYMS genes in patients with non-small cell lung cancer

2015 ◽  
Vol 10 (3) ◽  
pp. 937-941 ◽  
Author(s):  
SHENGJIE SUN ◽  
WEIWEI SHI ◽  
ZHIYONG WU ◽  
GUOQING ZHANG ◽  
BO YANG ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Mrna Expression ◽  
Cell Lung Cancer ◽  
Prognostic Significance ◽  
Small Cell ◽  
Small Cell Lung

scholarly journals Prognostic Significance of Stromal Periostin Expression in Non-Small Cell Lung Cancer

2020 ◽  
Vol 21 (19) ◽  
pp. 7025
Author(s):  
Katarzyna Ratajczak-Wielgomas ◽  
Alicja Kmiecik ◽  
Jedrzej Grzegrzołka ◽  
Aleksandra Piotrowska ◽  
Agnieszka Gomulkiewicz ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Prognostic Factor ◽  
Small Cell Lung Cancer ◽  
Mrna Expression ◽  
Cancer Cells ◽  
Cell Lung Cancer ◽  
Prognostic Significance ◽  
Immunohistochemical Analysis ◽  
Small Cell ◽  
Small Cell Lung

Background: The microenvironment of solid tumours is significant in cancer development and progression. The aim of this study was to determine periostin (POSTN) expression by cancer-associated fibroblasts (CAFs) in non-small-cell lung cancer (NSCLC), as well as to assess associations with clinicopathological factors and prognosis. Materials and Methods: Immunohistochemical analysis of POSTN expression was performed on NSCLC (N = 700) and non-malignant lung tissue (NMLT) (N = 110) using tissue microarrays. Laser capture microdissection (LCM) for isolation of stromal and cancer cells of NSCLC was employed, and subsequently, POSTN mRNA expression was detected by real-time PCR. Immunofluorescence reaction and colocalisation analysis were performed by confocal microscopy. Results: Expression of POSTN in CAFs was significantly higher in NSCLC and in the adenocarcinoma (AC) and squamous cell carcinoma (SCC) subtypes compared to NMLT. POSTN expression in CAFs increased with clinical cancer stage, grades (G) of malignancy, and lymph node involvement in NSCLC. Higher POSTN expression in CAFs was an independent prognostic factor for overall survival (OS). LCM confirmed significantly higher POSTN mRNA expression in the stromal cells (CAFs) compared to the lung cancer cells. Conclusions: POSTN produced by CAFs might be crucial for NSCLC progression and can be an independent negative prognostic factor in NSCLC.

scholarly journals Prognostic Significance of Cyclooxygenase 2 mRNA Expression in Non-Small Cell Lung Cancer

2002 ◽  
Vol 235 (3) ◽  
pp. 440-443 ◽  
Author(s):  
Jan Brabender ◽  
JiMin Park ◽  
Ralf Metzger ◽  
Paul M. Schneider ◽  
Reginald V. Lord ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Mrna Expression ◽  
Cell Lung Cancer ◽  
Prognostic Significance ◽  
Small Cell ◽  
Cyclooxygenase 2 ◽  
Small Cell Lung

Prognostic Significance of Perioperative C-Reactive Protein in Resected Non-Small Cell Lung Cancer

2020 ◽  
Vol 32 (4) ◽  
pp. 1046-1055 ◽  
Author(s):  
Satoru Okada ◽  
Masanori Shimomura ◽  
Hiroaki Tsunezuka ◽  
Satoshi Teramukai ◽  
Shunta Ishihara ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Prognostic Significance ◽  
Small Cell ◽  
C Reactive Protein ◽  
Small Cell Lung ◽  
Reactive Protein

The Prognostic Significance of Circulating Tumour Cells in Head and Neck and Non-Small Cell Lung Cancer

2018 ◽  
Author(s):  
Arutha Kulasinghe ◽  
Joanna Kapeleris ◽  
Rebecca Kimberley ◽  
Stephen R Mattarollo ◽  
Erik W Thompson ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Head And Neck ◽  
Cell Lung Cancer ◽  
Prognostic Significance ◽  
Small Cell ◽  
Tumour Cells ◽  
Circulating Tumour Cells ◽  
Small Cell Lung

scholarly journals P72.10 Prognostic Significance of IgA+ B Cells in Non-Small Cell Lung Cancer

2021 ◽  
Vol 16 (3) ◽  
pp. S569
Author(s):  
M. Vanderputten ◽  
F. Aboubakar ◽  
C. Bouzin ◽  
D. Hoton ◽  
C. Stanciu Pop ◽  
...  
Keyword(s):  
Lung Cancer ◽  
B Cells ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Prognostic Significance ◽  
Small Cell ◽  
Small Cell Lung

Patterns and prognostic significance of cutaneous immune-related adverse events in non–small cell lung cancer

2021 ◽  
Vol 147 ◽  
pp. 13-16
Author(s):  
Leah L. Thompson ◽  
Emily R. Nadelmann ◽  
Amy E. Blum ◽  
Jaewon Yoon ◽  
Nicole J. Polyakov ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Adverse Events ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Prognostic Significance ◽  
Small Cell ◽  
Small Cell Lung
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