scholarly journals Plasma concentrations of adrenomedullin and natriuretic peptides in patients with essential hypertension

2015 ◽  
Vol 9 (5) ◽  
pp. 1901-1908 ◽  
Author(s):  
WEI HU ◽  
PANG-HU ZHOU ◽  
XIAO-BIN ZHANG ◽  
CHANG-GENG XU ◽  
WEI WANG
Keyword(s):  
Essential Hypertension ◽  
Natriuretic Peptides ◽  
Plasma Concentrations

Reduced Plasma Concentrations of Nitrogen Oxide in Individuals With Essential Hypertension

Hypertension ◽  
1997 ◽  
Vol 30 (3) ◽  
pp. 405-408 ◽  
Author(s):  
Koichi Node ◽  
Masafumi Kitakaze ◽  
Hiromichi Yoshikawa ◽  
Hiroaki Kosaka ◽  
Masatsugu Hori
Keyword(s):  
Essential Hypertension ◽  
Nitrogen Oxide ◽  
Plasma Concentrations

ATRIAL NATRIURETIC PEPTIDES IN ESSENTIAL HYPERTENSION

The Lancet ◽  
1986 ◽  
Vol 327 (8480) ◽  
pp. 562 ◽  
Author(s):  
T.M.Mac Donald ◽  
R.F. Jeffrey ◽  
M.R. Lee
Keyword(s):  
Essential Hypertension ◽  
Natriuretic Peptides ◽  
Atrial Natriuretic Peptides ◽  
Atrial Natriuretic

scholarly journals Perioperative Plasma Concentrations of Atrial and Brain Natriuretic Peptides in Patients Undergoing Hip Arthroplasty

2002 ◽  
Vol 30 (5) ◽  
pp. 588-590 ◽  
Author(s):  
K. Terasako
Keyword(s):  
Blood Pressure ◽  
Hip Arthroplasty ◽  
Natriuretic Peptides ◽  
Plasma Concentrations ◽  
Prospective Clinical Study ◽  
Brain Natriuretic Peptides ◽  
Acute Hypotension ◽  
Cemented Arthroplasty ◽  
The Relationship ◽  
Hypotensive Response

Acute hypotension, transient hypoxaemia and elevation of pulmonary artery pressure are well known to occur during cemented arthroplasty. The aim of this prospective clinical study was to characterize the relationship between plasma concentrations of atrial and brain natriuretic peptides (ANP, BNP), and changes in blood pressure in patients undergoing hip arthroplasty. Elevated ANP and BNP levels may be markers of inadequate myocardial reserve. We measured plasma ANP and BNP levels before the operation and 20 minutes after the cementing in 18 patients (54–90 yr). We defined a hypotensive response after cementing as a decrease in systolic blood pressure of more than 15 mm Hg below the pre-cementing value. In the hypotensive group, preoperative values of ANP were 123±48.5 pg/ml and BNP, 138±71.7 pg/ml. These values are significantly greater than those in the normotensive group (ANP 35.9± 7.7, and BNP 17.2±3.2 pg/ml). High preoperative values of ANP and BNP are associated with more hypotension during cemented arthroplasty and could provide an indication of which patients are at risk of this complication.

scholarly journals Stability of plasma concentrations of N- and C-terminal atrial natriuretic peptides at room temperature.

Heart ◽  
1997 ◽  
Vol 77 (4) ◽  
pp. 392-392
Author(s):  
G. McDowell ◽  
C. Shaw ◽  
K. D. Buchanan ◽  
D. P. Nicholls
Keyword(s):  
Natriuretic Peptides ◽  
Room Temperature ◽  
Plasma Concentrations ◽  
Atrial Natriuretic Peptides ◽  
Atrial Natriuretic

Plasma levels of atrial natriuretic peptides during pregnancy and post partum in the rat

1989 ◽  
Vol 120 (1) ◽  
pp. 113-117 ◽  
Author(s):  
C. Jansakul ◽  
R. G. King ◽  
A. L. A. Boura ◽  
S. P. Brennecke ◽  
G. M. Handberg
Keyword(s):  
Plasma Volume ◽  
Natriuretic Peptides ◽  
Post Partum ◽  
Plasma Concentrations ◽  
Maternal Plasma ◽  
Atrial Natriuretic Peptides ◽  
Female Wistar Rats ◽  
Near Term ◽  
The Relationship ◽  
Atrial Natriuretic

ABSTRACT Plasma concentrations of atrial natriuretic peptides (ANP) in female Wistar rats were measured by radioimmunoassay at oestrus, during pregnancy, during parturition and between 3 h and 4 days post partum. Concentrations of ANP in rats on days 10, 15 and 17 of pregnancy were not significantly different from those in non-pregnant animals in oestrus (32·5 ± 2·2 pmol/l; mean ± s.e.m., n = 9), but levels near term (days 20 and 21 of pregnancy) were reduced by approximately 50%. However, plasma concentrations of ANP at 6, 12 and 24 h post partum were approximately twice those of non-pregnant animals in oestrus, but returned to normal levels within 4 days after parturition. Maternal plasma volume increased significantly during pregnancy, and fell 15–20% 6–24 h post partum. These results suggest that the relationship between plasma volume and the plasma concentration of ANP is reset during pregnancy and changes rapidly post partum. The results do not necessarily, however, imply any changes in the relationship between atrial pressure and the concentration of ANP. Journal of Endocrinology (1989) 120, 113–117

Vigorous response in plasma N-terminal pro-brain natriuretic peptide (NT-BNP) to acute myocardial infarction

2004 ◽  
Vol 106 (2) ◽  
pp. 135-139 ◽  
Author(s):  
Denzil GILL ◽  
Timothy SEIDLER ◽  
Richard W. TROUGHTON ◽  
Timothy G. YANDLE ◽  
Christopher M. FRAMPTON ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Natriuretic Peptides ◽  
Troponin T ◽  
Plasma Concentrations ◽  
Creatine Kinase Mb ◽  
Multiple Blood ◽  
Multiple Samples

Acute myocardial infarction (MI) results in activation of neurohormonal systems and increased plasma concentrations of myocardial enzymes and structural proteins. We hypothesized that plasma levels of N-terminal pro-brain natriuretic peptide (NT-BNP) would respond more vigorously after MI than those of other natriuretic peptides. We also sought to compare this response with that of the established myocardial injury markers troponin T (TnT), myoglobin and creatine kinase MB (CK-MB). We obtained multiple blood samples for measurement of atrial natriuretic peptide (ANP), N-terminal pro-ANP, brain natriuretic peptide (BNP) and NT-BNP along with CK-MB, TnT and myoglobin in 24 patients presenting to the Coronary Care Unit within 6 h of onset of MI. Multiple samples were obtained in the first 24 h, then at 72 h, 1 week, 6 weeks and 12 weeks. NT-BNP increased rapidly to peak at 24 h and exhibited greater (P<0.001) absolute increments from baseline compared with BNP and ANP, whereas NT-ANP did not change from baseline. Proportional increments in NT-BNP were also greater than those for the other natriuretic peptides (P<0.05). Natriuretic peptide levels reached their peak around 24 h, later than peak TnT, CK-MB and myoglobin (peak between 1–10 h), and NT-BNP and ANP remained elevated on average for 12 weeks. Our present results, with detailed sampling of a cohort of acute MI patients, demonstrate greater absolute and proportional increments in NT-BNP than ANP or BNP with sustained elevation of these peptides at 12 weeks.

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