scholarly journals Detection of serum VEGF and MMP-9 levels by Luminex multiplexed assays in patients with breast infiltrative ductal carcinoma

2014 ◽  
Vol 8 (1) ◽  
pp. 175-180 ◽  
Author(s):  
JUNYING ZHANG ◽  
LI YIN ◽  
JIANZHONG WU ◽  
YE ZHANG ◽  
TAO XU ◽  
...  
2013 ◽  
Vol 20 (12) ◽  
pp. 3831-3838 ◽  
Author(s):  
Isabelle Jaffré ◽  
Loic Campion ◽  
Magali Dejode ◽  
Virginie Bordes ◽  
Christine Sagan ◽  
...  

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Alaa Othama Hendawy Ghanem ◽  
Yasser Ibrahim Abd Elkhalek ◽  
Mohamed Gamal Aldin Abd Elmoteleb

Abstract Background Mammography and Sonography are the important sensitive imaging modalities available in detection of breast cancer. Sonoelastography is a relatively new imaging technique which acts as a complementary tool to improve the diagnostic ability of ultrasound for evaluating patients with breast masses. Objective To evaluate the role of sonoelastography characterization information on solid breast lesions over conventional sonography and mammography either benign or malignant lesions to reduce the number of benign biopsies performed. Methods A prospective study was carried at private centers, starting from august 2019 till december 2019. Results The study conducted on 40 patients with palpable breast lesions classified to BIRADS 3 and 4a according to conventional ultrasound and mammographic criteria. Their ages ranged from 18 to '75 years with a mean age 47.72 14.91, 22 cases (55%) had no family history of pervious breast disease, and 18 cases (45%) had family history of pervious breast disease. All patients were subjected to full history taking, clinical examination, conventional gray scale ultrasound, and mammography and ultrasound elastography. All patients underwent histopathological assessment to reach the final diagnosis. Among Studied cases , 28 lesions were sampled by fine needle biopsy (70%) and 12 lesions were sampled by true cut needle (30%) .the results revealed 27 breast lesions were benign (67.5%), 9 malignant lesions (22.5%) and 4 lesions shows atypia (10%) according to histopathological assessment. Among final diagnosis of breast lesions fibro adenoma was the most frequent benign breast lesion detected as 12 lesions from 27 benign breast lesions were fibroadenoma., Also infiltrative ductal carcinoma was the moste frequent among malignant breast lesions as 5 lesions from 9 malignant lesions were infiltrative ductal carcinoma. Conclusion Ultrasoundelastography has significant complementray role beside conventional mammogram and ultrasound in characterization of solid breast lesions.


2014 ◽  
Vol 11 (Supplement 1) ◽  
Author(s):  
Mehmet Erikoğlu ◽  
Gürcan Şimşek ◽  
Çağlayan Dereli ◽  
Şakir Tavlı

2019 ◽  
Vol 2019 ◽  
pp. 1-2
Author(s):  
Iris Y. Sheng ◽  
Megan Kruse ◽  
Kathryn M. Leininger ◽  
Moshe C. Ornstein

Synchronous tumors are defined as two tumors arising concurrently or within six months of each other. Reports of synchronous RCC and breast cancer are limited to nonmetastatic renal cell carcinoma (RCC) and hormone receptor-positive infiltrative ductal carcinoma. We present the first case of synchronous metastatic renal cell carcinoma and metastatic triple-negative breast cancer, managed with a novel combination of immunotherapy and chemotherapy.


2018 ◽  
Vol 84 (6) ◽  
pp. 856-861 ◽  
Author(s):  
Rui Du ◽  
Hao Zhang ◽  
Weiwei Shu ◽  
Baoding Chen ◽  
Yuefeng Li ◽  
...  

Breast cancer causes great threats to public health worldwide. The aim of this study was to investigate the correlation between Ki-67 expression and the hemodynamics of contrast-enhanced ultrasound (CEUS) in patients with infiltrative ductal carcinoma (IDC). CEUS was performed on 109 masses in 85 IDC cases before resection. Based on the immunohistochemical staining on the antigen Ki-67, the masses were divided into negative group, weakly positive group, positive group, and strong-positive group. Significant statistical differences were noticed in time to peak, arrive intensity, and peak intensity in the positive groups compared with the negative group. Compared with the positive groups, the negative group showed significant statistical differences in arrive intensity and peak intensity. The antigen Ki-67 was positively correlated with arrived intensity, intensity changes, and rising curve's slope. In contrast, it was negatively correlated with arrived time, time to peak, and continuous time. The hemodynamic parameters of CEUS were correlated with the expression of antigen Ki-67. On this basis, Ki-67 is an effective supplement to the diagnosis of IDC.


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