scholarly journals Cell culture of human gingival fibroblasts, oral cancer cells and mesothelioma cells with serum-free media, STK1 and STK2

2014 ◽  
Vol 2 (5) ◽  
pp. 644-648 ◽  
Author(s):  
YUTA TSUGENO ◽  
FUYUKI SATO ◽  
YASUTERU MURAGAKI ◽  
YUKIO KATO
Keyword(s):  
Cell Culture ◽  
Oral Cancer ◽  
Cancer Cells ◽  
Human Gingival Fibroblasts ◽  
Gingival Fibroblasts ◽  
Serum Free ◽  
Oral Cancer Cells ◽  
Free Media

In Vitro Anticancer Activity of Virgin Coconut Oil and its Fractions in Liver and Oral Cancer Cells

2020 ◽  
Vol 19 (18) ◽  
pp. 2223-2230 ◽  
Author(s):  
Poonam Verma ◽  
Sanjukta Naik ◽  
Pranati Nanda ◽  
Silvi Banerjee ◽  
Satyanarayan Naik ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Oral Cancer ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Cell Line ◽  
Coconut Oil ◽  
Virgin Coconut Oil ◽  
Anticancer Efficacy ◽  
Oral Cancer Cells

Background: Coconut oil is an edible oil obtained from fresh, mature coconut kernels. Few studies have reported the anticancer role of coconut oil. The fatty acid component of coconut oil directly targets the liver by portal circulation and as chylomicron via lymph. However, the anti-cancer activity of coconut oil against liver cancer cells and oral cancer cells is yet to be tested. The active component of coconut oil, that is responsible for the anticancer activity is not well understood. In this study, three different coconut oils, Virgin Coconut Oil (VCO), Processed Coconut Oil (PCO) and Fractionated Coconut Oil (FCO), were used. Objective: Based on previous studies, it can be hypothesized that fatty acids in coconut oil may have anticancer potential and may trigger cell death in cancer cell lines. Methods: Each cell line was treated with different concentrations of Virgin Coconut Oil (VCO), Processed Coconut Oil (PCO) and Fractionated Coconut Oil (FCO). The treated cells were assayed by MTT after 72 hr of incubation. The fatty acid composition of different coconut oils was analyzed by gas chromatography. Result: Different concentrations of coconut oils were used to treat the cells. Interestingly, the anticancer efficacy of VCO, PCO and FCO was not uniform, rather the efficacy varied from cell line to cell line. Only 20% VCO showed significant anticancer activity in HepG2 cells in comparison to 80% PCO against the KB cell line. Remarkably, 20% of PCO and 5% of FCO showed potential growth inhibition in the KB cell line as compared to 80% PCO in HepG2 cells. Moreover, there was a difference in the efficacy of VCO, PCO and FCO, which might be due to their fatty acid composition. Comparing the anticancer efficacy of VCO, PCO and FCO in this study helped to predict which class of fatty acids and which fatty acid might be associated with the anticancer activity of VCO. Conclusion: This study shows that VCO, PCO and FCO have anticancer efficacy and may be used for the treatment of cancer, especially liver and oral cancer.

Econazole-induced Ca2+ fluxes and apoptosis in human oral cancer cells

2010 ◽  
Vol 71 (4) ◽  
pp. 240-248 ◽  
Author(s):  
Daih-Huang Kuo ◽  
Li-Min Liu ◽  
Hsin-Wei Chen ◽  
Fu-An Chen ◽  
Chung-Ren Jan
Keyword(s):  
Oral Cancer ◽  
Cancer Cells ◽  
Oral Cancer Cells

Effect of the environmental pollutant bisphenol A dimethacylate (BAD) on Ca2+ movement and viability in OC2 human oral cancer cells

2013 ◽  
Vol 35 (2) ◽  
pp. 178-184 ◽  
Author(s):  
Jau-Min Chien ◽  
Chiang-Ting Chou ◽  
Yi-Chau Lu ◽  
Ti Lu ◽  
Chao-Chuan Chi ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Bisphenol A ◽  
Cancer Cells ◽  
Environmental Pollutant ◽  
Oral Cancer Cells

Apoptotic effect of cisplatin and cordycepin on OC3 human oral cancer cells

2013 ◽  
Vol 20 (8) ◽  
pp. 624-632 ◽  
Author(s):  
Ying-hui Chen ◽  
Lyh-Jyh Hao ◽  
Chih-peng Hung ◽  
Jung-wei Chen ◽  
Sew-fen Leu ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Cells ◽  
Apoptotic Effect ◽  
Oral Cancer Cells

Quercetin Inhibits Proliferation and Drug Resistance in KB/VCR Oral Cancer Cells and Enhances Its Sensitivity to Vincristine

2014 ◽  
Vol 67 (1) ◽  
pp. 126-136 ◽  
Author(s):  
Zhaohu Yuan ◽  
Huili Wang ◽  
Ziyou Hu ◽  
Yanqing Huang ◽  
Fang Yao ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Oral Cancer ◽  
Cancer Cells ◽  
Oral Cancer Cells
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