scholarly journals Association of human leukocyte antigen gene polymorphism and mesangial proliferative glomerulonephritis in a large population-based study

2013 ◽  
Vol 1 (5) ◽  
pp. 751-756
Author(s):  
JING-JIE ZHAO ◽  
XI-BING WANG ◽  
YUN LUAN ◽  
JUN-LI LIU ◽  
LING LIU ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Human Leukocyte Antigen ◽  
Large Population ◽  
Human Leukocyte ◽  
Population Based ◽  
Proliferative Glomerulonephritis ◽  
Mesangial Proliferative Glomerulonephritis ◽  
Population Based Study ◽  
Human Leukocyte Antigen Gene ◽  
Leukocyte Antigen

Human Leukocyte Antigen Class II and Cervical Cancer Risk: A Population‐Based Study

2002 ◽  
Vol 186 (11) ◽  
pp. 1565-1574 ◽  
Author(s):  
Margaret M. Madeleine ◽  
Babette Brumback ◽  
Kara L. Cushing‐Haugen ◽  
Stephen M. Schwartz ◽  
Janet R. Daling ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Risk ◽  
Human Leukocyte Antigen ◽  
Human Leukocyte Antigen Class ◽  
Human Leukocyte ◽  
Class Ii ◽  
Population Based ◽  
Population Based Study ◽  
Leukocyte Antigen ◽  
Cervical Cancer Risk

HLA class I alleles are associated with clinic-based migraine and increased risks of chronic migraine and medication overuse

Cephalalgia ◽  
2020 ◽  
Vol 40 (5) ◽  
pp. 493-502
Author(s):  
Claire Huang ◽  
Shih-Pin Chen ◽  
Yu-Han Huang ◽  
Hsuan-Yu Chen ◽  
Yen-Feng Wang ◽  
...  
Keyword(s):  
Human Leukocyte Antigen ◽  
Chronic Migraine ◽  
Medication Overuse ◽  
Medical Center ◽  
Medication Overuse Headache ◽  
Human Leukocyte ◽  
Population Based ◽  
Class I ◽  
Leukocyte Antigen ◽  
Antigen B

Objective We aimed to evaluate associations of human leukocyte antigen variants with migraine or headache in hospital and population-based settings. Methods The case-control study population, aged 30–70, included 605 clinic-based migraine patients in a medical center and 8449 population-based participants in Taiwan Biobank (TWB). Clinic-based cases were ascertained by neurologists. Participants in Taiwan Biobank were interviewed by a structured questionnaire including headache and migraine history; among them, 2394 had headache or migraine history while 6055 were free of headache and served as controls. All subjects were genotyped by Axiom Genome-Wide Single Nucleotide Polymorphism Arrays and imputed for eight classical human leukocyte antigen genes. Human leukocyte antigen frequencies were compared between clinic-based and self-reported patients and controls. We utilized likelihood ratio tests to examine human leukocyte antigen-disease associations and logistic regressions to estimate the effect of human leukocyte antigen alleles on migraine. Results Human leukocyte antigen -B and C showed significant associations with clinic-based migraine ( q-value < 0.05). Human leukocyte antigen -B*39:01, human leukocyte antigen -B*51:01, human leukocyte antigen -B*58:01 and human leukocyte antigen -C*03:02 were significantly associated with migraine, with age and sex-adjusted odds ratios (95% CIs) of 1.80 (1.28–2.53), 1.50 (1.15–1.97), 1.36 (1.14–1.62) and 1.36 (1.14–1.62), correspondingly. Clinic-based migraineurs carrying human leukocyte antigen -B*58:01 or human leukocyte antigen -C*03:02 had 1.63 (1.11–2.39) -fold likelihood to have chronic migraine with medication-overuse headache compared to episodic migraine. However, no human leukocyte antigen genes were associated with self-reported headache or migraine in the community. Conclusions Human leukocyte antigen class I genetic variants are positively associated with risk of clinic-based migraine but not self-reported migraine or headache and may contribute to migraine chronification and medication overuse.

Association of Human Leukocyte Antigen-(HLA-B 27) Gene Polymorphism with Vitiligo Disease

2019 ◽  
Vol 10 (8) ◽  
pp. 2307
Author(s):  
Mona N. Al-Terehi ◽  
Zainab Abbas Al-Talebi ◽  
Abbas Hussein Mugheer ◽  
Ali H. Al-Saadi ◽  
Fathia ATeeq Rajab
Keyword(s):  
Gene Polymorphism ◽  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Leukocyte Antigen

Killer cell immunoglobulin-like receptor and human leukocyte antigen gene profiles in a cohort of HIV-infected Mexican Mestizos

2016 ◽  
Vol 68 (9) ◽  
pp. 703-717 ◽  
Author(s):  
Daniela Garrido-Rodríguez ◽  
Santiago Ávila-Ríos ◽  
Claudia García-Morales ◽  
Humberto Valenzuela-Ponce ◽  
Christopher Ormsby ◽  
...  
Keyword(s):  
Human Leukocyte Antigen ◽  
Killer Cell ◽  
Human Leukocyte ◽  
Human Leukocyte Antigen Gene ◽  
Leukocyte Antigen ◽  
Antigen Gene ◽  
Gene Profiles ◽  
Mexican Mestizos
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