scholarly journals In vitro effect of molluscan hemocyanins on CAL-29 and T-24 bladder cancer cell lines

2012 ◽  
Vol 1 (2) ◽  
pp. 235-238 ◽  
Author(s):  
OLGA BOYANOVA ◽  
PAVLINA DOLASHKA ◽  
DRAGA TONCHEVA ◽  
HANS-GEORG RAMMENSEE ◽  
STEFAN STEVANOVIĆ
Keyword(s):  
Bladder Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell ◽  
Vitro Effect

Synergistic Antitumor Effects of Fleroxacin With 5-fluorouracil In Vitro and In Vivo for Bladder Cancer Cell Lines

Urology ◽  
2009 ◽  
Vol 74 (6) ◽  
pp. 1370-1376 ◽  
Author(s):  
Toru Nishikawa ◽  
Yasuo Kohjimoto ◽  
Masaya Nishihata ◽  
Shoichi Ebisuno ◽  
Isao Hara
Keyword(s):  
Bladder Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell ◽  
Antitumor Effects

scholarly journals In vitro assessment of intra-operative and post-operative environment in reducing bladder cancer recurrence

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Ryan Tsz-Hei Tse ◽  
Hongda Zhao ◽  
Christine Yim-Ping Wong ◽  
Angel Wing-Yan Kong ◽  
Ronald Cheong-Kin Chan ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Recurrence Rate ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Recurrence ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell ◽  
Sterile Water ◽  
Bladder Cancer Recurrence

AbstractUrinary bladder cancer is a common cancer worldwide. Currently, the modality of treating and monitoring bladder cancer is wide. Nonetheless, the high recurrence rate of non-muscle-invasive bladder cancer after surgical resection is still unsatisfactory. Hereby, our study demonstrated whether the intra-operative and post-operative environments will affect bladder cancer recurrence utilizing in vitro cell line model. Bladder cancer cell lines were submerged in four different irrigating fluids for assessing their tumorigenic properties. Our results showed that sterile water performed the best in terms of the magnitude of cytotoxicity to cell lines. Besides, we also investigated cytotoxic effects of the four irrigating agents as well as mitomycin C (MMC) in normothermic and hyperthermic conditions. We observed that sterile water and MMC had an increased cytotoxic effect to bladder cancer cell lines in hyperthermic conditions. Altogether, our results could be translated into clinical practice in the future by manipulating the intra-operative and post-operative conditions in order to lower the chance of residual cancer cells reimplant onto the bladder, which in turns, reducing the recurrence rate of bladder cancers.

scholarly journals 19-(Benzyloxy)-19-oxojolkinolide B (19-BJB), an ent-abietane diterpene diepoxide, inhibits the growth of bladder cancer T24 cells through DNA damage

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248468
Author(s):  
Ke Wang ◽  
Juan-Cheng Yang ◽  
Yeong-Jiunn Jang ◽  
Guan-Yu Chen ◽  
Ya-Jing Zhang ◽  
...  
Keyword(s):  
Dna Damage ◽  
Bladder Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
3D Qsar ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell ◽  
Checkpoint Kinase

Diterpenoids jolkinolide A and B, were first isolated from Euphorbia fischeriana. In our previous research, 19-(Benzyloxy)-19-oxojolkinolide B (19-BJB), a derivative of jolkinolides, was synthesized as a novel ent -abietane diterpene diepoxide. In this study, 19-BJB showed strong in vitro activity against bladder cancer cell lines. DNA damage which was observed through the interaction of 19-BJB with nucleotide chains and affected DNA repair resulted in the activation of checkpoint kinase 1 (Chk1) and checkpoint kinase 2 (Chk2) in bladder cancer cell lines. In vivo testing in nude mice also proved that 19-BJB revealed a potential inhibitory effect on tumor growth. Additionally, the 3D-QSAR models of jolkinolides were established. Briefly, we proved that 19-BJB could potentially be used as a drug to inhibit the growth of bladder tumor.

scholarly journals Protein expression profile related to cisplatin resistance in bladder cancer cell lines detected by two-dimensional gel electrophoresis

2015 ◽  
Vol 36 (4) ◽  
pp. 253-261 ◽  
Author(s):  
Yoshinori TAOKA ◽  
Kazumasa MATSUMOTO ◽  
Kazuya OHASHI ◽  
Satoru MINAMIDA ◽  
Masahiro HAGIWARA ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Protein Expression ◽  
Cell Lines ◽  
Cancer Cell ◽  
Expression Profile ◽  
Cisplatin Resistance ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell ◽  
Two Dimensional ◽  
Protein Expression Profile

Effects of Diethyl Spermine Analogues in Human Bladder Cancer Cell Lines in Culture

1993 ◽  
Vol 150 (4) ◽  
pp. 1293-1297 ◽  
Author(s):  
Barbara K. Chang ◽  
Yayun Liang ◽  
David W. Miller ◽  
Raymond J. Bergeron ◽  
Carl W. Porter ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell ◽  
Human Bladder Cancer ◽  
Human Bladder ◽  
Human Bladder Cancer Cell ◽  
Spermine Analogues
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