scholarly journals The One Step Melanoma Surgery (OSMS): A New Chance for More Adequate Surgical Treatment of Melanoma Patients!?

2019 ◽  
Vol 7 (3) ◽  
pp. 504-506
Author(s):  
Georgi Tchernev ◽  
Ivanka Temelkova
Keyword(s):  
Surgical Treatment ◽  
Correct Choice ◽  
Thickness Measurement ◽  
Tumour Thickness ◽  
Melanoma In Situ ◽  
The Status ◽  
One Step ◽  
Melanoma Patients ◽  
The One

One step melanoma surgery (OSMS) is applicable to all patients with clear clinical and dermatoscopic criteria for thin cutaneous melanomas or melanoma in situ lesions, even without the need for preoperative tumour thickness measurement. Amelanotic melanomas and melanomas with clinical and dermatoscopical features for regression zones could be problematic when applying the OSMS.  The methodology could be also applicable to all groups of patients where the tumour thickness could be measured preoperatively/by ultrasound (while in parallel also determining the status of the locoregional lymph nodes). For tumours with a tumour thickness between 2 and 4 mm, but also over 4mm the OSMS seems to be the correct choice.

scholarly journals Analysis of the Influence of Fibers on the Formability of Metal Blanks in Manufacturing Processes for Fiber Metal Laminates

2019 ◽  
Vol 3 (1) ◽  
pp. 2 ◽  
Author(s):  
Thomas Mennecart ◽  
Soeren Gies ◽  
Noomane Ben Khalifa ◽  
A. Erman Tekkaya
Keyword(s):  
Contact Forces ◽  
Starting Time ◽  
Fiber Metal Laminate ◽  
Metal Sheets ◽  
Different Types ◽  
One Step ◽  
Fiber Metal ◽  
The One ◽  
Metal Blank

In the one-step manufacturing process for fiber metal laminate parts, the so-called in situ hybridization process, the fabrics are interacting with metal blanks. During deep drawing, the liquid matrix is injected between the metal sheets through the woven fiber layers. The metal blanks can be in contact with dry or with infiltrated fibers. The formability of the blanks is influenced by the variation of the starting time of injection. The reason for that is that, due to high contact forces, the fibers are able to deform the metal surface locally, so that movement and the strain of the blanks is inhibited. To investigate the influence of different fibers on the formability of metals, Nakazima tests are performed. In these tests, two metal blanks are formed with an interlayer of fibers. The results are compared with the formability of two blanks without any interlayer. It is shown that in with fibers between sheets, the formability decreases compared to the formability of two metal blanks without interlayers. Based on a simplified numerical model for different types of fibers, the interactions of the fibers with the metal blank are analyzed. It could be shown that the friction due to contact has more influence than the friction due to the form fit caused by the imprints.

In-situ regeneration mechanisms of hybrid catalysts in the one-step synthesis of dimethyl ether from syngas

2007 ◽  
Vol 115 (1-2) ◽  
pp. 23-26 ◽  
Author(s):  
Youshun Luan ◽  
Hengyong Xu ◽  
Chunying Yu ◽  
Wenzhao Li ◽  
Shoufu Hou
Keyword(s):  
Dimethyl Ether ◽  
Hybrid Catalysts ◽  
In Situ Regeneration ◽  
One Step ◽  
The One ◽  
Synthesis Of Dimethyl Ether

scholarly journals 1-(4-Nitrophenyl)-1H-1,2,3-Triazole-4-carbaldehyde: Scalable Synthesis and Its Use in the Preparation of 1-Alkyl-4-Formyl-1,2,3-triazoles

Organics ◽  
2021 ◽  
Vol 2 (4) ◽  
pp. 404-414
Author(s):  
Tomas Opsomer ◽  
Kaat Valkeneers ◽  
Ana Ratković ◽  
Wim Dehaen
Keyword(s):  
One Pot ◽  
Complete Hydrolysis ◽  
One Step ◽  
Synthetic Intermediates ◽  
Cornforth Rearrangement ◽  
Scalable Synthesis ◽  
The One ◽  
Novel Applications ◽  
Hydrolysis Of

1,2,3-Triazole-4-carbaldehydes are useful synthetic intermediates which may play an important role in the discovery of novel applications of the 1,2,3-triazole moiety. In this work, a one-step multigram scale synthesis of 4-formyl-1-(4-nitrophenyl)-1H-1,2,3-triazole (FNPT) as a preferred reagent for the synthesis of 1-alkyl-4-formyltriazoles is described, making use of the commercially available 3-dimethylaminoacrolein and 4-nitrophenyl azide. Next, the earlier reported reaction of FNPT with alkylamines is further explored, and for hexylamine, the one-pot sequential cycloaddition and Cornforth rearrangement is demonstrated. In addition, a useful protocol for the in situ diazotization of 4-nitroaniline is provided. This facilitated the complete hydrolysis of rearranged 4-iminomethyl-1,2,3-triazoles and allowed for the recycling of 4-nitrophenyl azide.

Surgical Treatment of Nail Apparatus Melanoma in situ: The Use of Artificial Dermis in Reconstruction

2012 ◽  
Vol 38 (4) ◽  
pp. 692-694 ◽  
Author(s):  
Koichi Hayashi ◽  
Hisashi Uhara ◽  
Hiroshi Koga ◽  
Ryuhei Okuyama ◽  
Toshiaki Saida
Keyword(s):  
Surgical Treatment ◽  
Melanoma In Situ ◽  
Artificial Dermis

scholarly journals Evaluation of outpatient discharge in patients with cutaneous melanoma

2015 ◽  
Vol 42 (2) ◽  
pp. 70-74
Author(s):  
Nurimar C. Fernandes ◽  
Flauberto de Sousa Marinho
Keyword(s):  
Cutaneous Melanoma ◽  
Cross Sectional Study ◽  
The Other ◽  
Stage Iiic ◽  
Cross Sectional ◽  
Melanoma In Situ ◽  
Stage Ia ◽  
The One

OBJECTIVE: to evaluate discharge in a group of patients with cutaneous melanoma according to recently established criteria. METHODS: we conducted an observational, cross-sectional study with 32 patients at the Hospital Universitário Clementino Fraga Filho (HUCFF) / Universidade Federal do Rio de Janeiro (UFRJ), between 1995 and 2013, in the following stages: IA (17 cases, 53.12%), IB (4 cases, 12.5%), IIA (3 cases, 9.37%), IIC (1 case, 3.12%), IIIB (1 case, 3.12%), IIIC (3 cases, 9.37%), melanomas in situ (2 cases, 6.25%), Tx (1 case, 3.12%). RESULTS: the follow-up time varied from one to 20 years (stage IA), five to 15 years (stage IB), six to 17 years (stage IIA), 20 years (stage IIC), 23 years (stage IIIB) and 14 to 18 years (stage IIIC). One melanoma in situ (subungueal) was discharged in the fourth year of follow-up and the other was promptly discharged. The Tx melanoma was followed for 12 years. We observed no relapses or recurrences in the period. CONCLUSION: although a controversial issue, it was possible to endorse the discharge of the patients since our follow-up time had already exceeded the one recommended by the other authors.

Pd/meso-CoO derived from in situ reduction of the one-step synthesized Pd/meso-Co3O4: high-performance catalysts for benzene combustion

2019 ◽  
Vol 43 (31) ◽  
pp. 12358-12368 ◽  
Author(s):  
Xingtian Zhao ◽  
Ran Zhang ◽  
Yuxi Liu ◽  
Jiguang Deng ◽  
Peng Xu ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
High Performance ◽  
Oxygen Activation ◽  
In Situ Reduction ◽  
Templating Method ◽  
One Step ◽  
The One

The 0.93Pd/meso-CoO is prepared via in situ reduction of 0.85Pd/meso-Co3O4 derived from KIT-6-templating method. The excellent catalytic activity of 0.93Pd/meso-CoO is related to the formed Pd0 species and good oxygen activation ability.

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