scholarly journals A Higher Rate of Iron Deficiency in Obese Pregnant Sudanese Women

2017 ◽  
Vol 5 (3) ◽  
pp. 285-289 ◽  
Author(s):  
Wisal Abbas ◽  
Ishag Adam ◽  
Duria A. Rayis ◽  
Nada G. Hassan ◽  
Mohamed F. Lutfi
Keyword(s):  
Body Mass Index ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Serum Ferritin ◽  
Linear Regression Analysis ◽  
Normal Weight ◽  
Negative Association ◽  
Deficiency Anemia ◽  
Obese Women ◽  
Blood Indices

AIM: To assess the association between obesity and iron deficiency (ID).MATERIAL AND METHODS: Pregnant women were recruited from Saad Abualila Hospital, Khartoum, Sudan, during January–April 2015. Medical history (age, parity, gestational age) was gathered using questionnaire.  Weight and height were measured, and body mass index (BMI) was calculated. Women were sub-grouped based on BMI into underweight (< 18.5 kg/m^2), normal weight (18.5–24.9 kg/m^2), overweight (25–29.9 kg/m^2) and obese (≥ 30 kg/m^2). Serum ferritin and red blood indices were measured in all studied women.RESULTS: Two (0.5%), 126 (29.8%), 224 (53.0%) and 71 (16.8%) out of the 423 women were underweight, normal weight, overweight and obese, respectively. Anemia (Hb <11 g/dl), ID (ferritin <15µg/l) and iron deficiency anemia (IDA) were prevalent in 57.7%, 21.3% and 12.1%, respectively. Compared with the women with normal BMI, significantly fewer obese women were anemic [25 (35.2%) vs. 108 (85.7%), P < 0.001] and significantly higher number of obese women [25 (35.2) vs. 22 (17.5, P = 0.015] had iron deficiency. Linear regression analysis demonstrated a significant negative association between serum ferritin and BMI (– 0.010 µg/, P= 0.006).CONCLUSION: It is evident from the current findings that prevalence of anaemia and ID showed different trends about BMI of pregnant women.

scholarly journals Iron Deficiency Anemia (IDA) in Pregnant Women of Different Ages in Swat District, Khyber Pakhtunkhwa Pakistan

2017 ◽  
Author(s):  
Atta Ullah ◽  
Ali Muhammad Yousafzai ◽  
Gul Nabi Khan ◽  
Nasir Iqbal ◽  
Bashir Ahmad
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Serum Ferritin ◽  
Serum Iron ◽  
Deficiency Anemia ◽  
Age Group ◽  
Second Trimester ◽  
Third Trimester ◽  
Hb Concentration

Abstract: The aim of this study was to find out the incidence of anemia in pregnant women of Swat District; to analyze the iron variations and its dietary effects.Data were collected during the periods of January &ndash; September 2016. The study of samples comprised of 250 pregnant women in the different trimester. Blood sample from each woman was collected and full blood count (FBC) was conducted through Mindray BC-3000 plus hem analyzer for all pregnant individuals. Confirmed anemic cases were then examined for IDA with serum ferritin, serum iron, total iron binding capacity (TIBC) through Randox kit and serum transferrin saturation was estimated by formula (serum ferritin saturation =serum iron &times;100/TIBC). The total number of participants in the first trimester were 50, among them 26 women were suffer from iron deficiency anemia (IDA) with 52% weightage of prevalence rate, (mean Hb concentration 9.602 &plusmn; 0.87 g/dl). The rates of IDA were 63.3%; ( mean Hb concentration 8.48 &plusmn; 1.24 g/dl) and 54%; ( mean Hb concentration 9.18 &plusmn; 1.28 g/dl), among 150 and 50 participants in the second and third trimester, respectively. A significant correlation was found between serum ferritin and Hb, serum ferritin against MCV and serum ferritin against MCH. The high prevalence of anemia was found 78.2% in the age group from 26-30 followed by 78.2% in the age group 36-40 years compared to those of other age groups in the second trimester. In this study the prevalence of IDA in third trimester is lower compared to first and second trimester.

scholarly journals SIGNIFICANCE OF INFLAMMATION MARKERS DETERMINED IN PREGNANT WOMEN WITH ANEMIC SYNDROME AND OBESITY

2018 ◽  
Vol 20 (5) ◽  
pp. 639-646
Author(s):  
Т. S. Prokhorenko ◽  
A. P. Zima ◽  
T. V. Saprina ◽  
N. N. Musina ◽  
N. S. Shakhmanova ◽  
...  
Keyword(s):  
Chronic Disease ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Chronic Diseases ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Obese Women ◽  
C Reactive Protein ◽  
Anemia Of Chronic Disease ◽  
Reactive Protein

The purpose of the present study was to specify a role of inflammatory mediators in pathogenesis of various types of anemia in pregnant obese women. We determined IL-1, IL-6, TNFα, C-reactive protein and hepcidin concentrations in blood serum of pregnant women with obesity depending on the type of anemic syndrome, either iron-deficiency anemia, or anemia of chronic diseases. We showed that the content of IL-6 in blood of the obese women exceeds the value of this index in healthy pregnant women (p < 0.05), and it does not depend on the presence and type of anemic syndrome. We found that the C-reactive protein concentration in pregnant women with obesity is higher than reference values (p < 0.05). Moreover, the contents of C-reactive protein in blood serum of pregnant women with anemia of chronic diseases is significantly higher (p < 0.05) than in women with iron deficiency anemia. Hepcidin concentration in blood of pregnant women with obesity and anemia of chronic disease was a specific feature: its content was significantly higher than in healthy pregnant women (p < 0.05), or in pregnant women with anemia-free obesity (p < 0.05). Hepcidin levels also exceeded 2-fold its contents in serum from pregnant women with obesity and iron deficiency anemia (p < 0.05). We have found that only pregnant women with obesity and anemia of chronic diseases have shown a positive correlation between the concentrations of C-reactive protein and blood levels of hepcidin (r = 0.733, p < 0.05), or IL-6 (r = 0.679, p < 0.05).The discussion concerns potential mechanisms of evolving anemia of chronic disease combined with subclinical inflammation in pregnant women with metabolic disorders. We conclude that a combination of obesity with gestational diabetes is a risk factor of anemia of chronic diseases in pregnant women. Development of an algorithm for differential diagnosis of iron deficiency anemia and anemia of chronic diseases in this cohort of patients is advisable for future studies in the area.

scholarly journals Predicting the risk of anemia in pregnant women with different somatotypes

2020 ◽  
Vol 11 (2) ◽  
pp. 43-50
Author(s):  
Tatiana I. Tsidaeva ◽  
Kristina G. Tomaeva ◽  
Sergey N. Gaidukov ◽  
Nikolai N. Rukhliada ◽  
Aida A. Cheldieva ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Serum Ferritin ◽  
Serum Iron ◽  
Hematological Parameters ◽  
First Trimester ◽  
Deficiency Anemia ◽  
Body Type ◽  
Latent Iron Deficiency

The aim of the study: to study the frequency of anemia in pregnant women with different somatotypes and to develop a model for predicting the risk of this pathology. Materials and methods. 390 women were examined. Of the women studied 110 were mаcrosomatotype, 173 mesosomatotype, and 107 microsomatotype. Somatometry was performed according to R.N. Dorokhov for women in early pregnancy (before 910 weeks of gestation). In blood test the level of hemoglobin, red blood cells, and hematocrit is determined using the Medonic M-series hematological automatic analyzer. Serum iron levels were determined colorimetrically with ferrosine. Serum ferritin levels were determined spectrophotometrically using ELISA methods. Results. It was found that iron deficiency anemia was significantly more common in pregnant women of macro-and microsomatic body type compared to women with mesosomatotypes (p 0.05). Pregnant women with severe anemia were not found. There were iron deficiency anemia of mild and moderate severity, and latent iron deficiency. Hematological parameters (hematocrit, serum iron, serum ferritin) were significantly lower in pregnant women with latent iron deficiency compared to women without anemia (p 0.05). Using multiple regression analysis, we obtained the regression equation (formula), which predicts the development of iron deficiency anemia in pregnant women of different somatotypes. Conclusions. The calculations according to the presented formula, allows to predict with high accuracy the prognosis of iron deficiency anemia in pregnant women, and also allows to form among patients a high-risk group for the development of this disease in the first trimester of pregnancy when the pregnant woman is registered in the womens consultation, which will contribute to more effective implementation of therapeutic and preventive measures to prevent the development of this pathology.

scholarly journals Coexistence of iron deficiency and thalassemia trait: a study in antenatal females

2017 ◽  
Vol 5 (12) ◽  
pp. 5362
Author(s):  
Sheetal Arora ◽  
Deepshikha Rana ◽  
Sujata Raychaudhuri ◽  
J. S. Dhupia
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Serum Ferritin ◽  
High Performance ◽  
Genetic Disorder ◽  
Family Health ◽  
Deficiency Anemia ◽  
Beta Thalassemia ◽  
World Population ◽  
Thalassemia Trait

Background: Thalassemia is most common genetic disorder worldwide and about 7% of world population is carrier. The prevalence of Beta thalassemia trait (BTT) is 3.5–10% in India. The National Family Health Survey (NFHS-3) of 2011 reveals the prevalence of iron deficiency anemia (IDA) as 70–80% in children, 70% in pregnant women, and 24% in adult men. As both of them are close differential diagnosis and both can coexist together, this study aims to detect hemoglobinopathies in pregnant women and quantify the effect of iron deficiency on HbA2 levels in order to improve the detection of β thalassemia trait with and without iron deficiency.Methods: Hb, RBC indices, and peripheral smears of 90 pregnant females with microcytic hypochromic blood picture were studied. Serum ferritin and HPLC (High Performance Liquid Chromatography) was performed. The results were analysed statistically by using SPSS version 16.0.Results: 93.3% patients had HbA2 <2%, 4.44% had >4.0% which characterise BTT and remaining 2.22% had between 3.0%-4.0%. HbA2 <2.0% may be seen in IDA, ATT, HbH disease and Delta thalassemia. 91.11% had reduced serum ferritin and 2.22% had normal ferritin levels.Conclusions: This study reveals that there is frequent occurrence of iron deficiency anaemia in patients with thalassemia traits. This can substantially invalidate the diagnosis of the latter. Hence, iron deficiency should be identified and rectified in patients with suspicion of thalassemia trait.

scholarly journals TEA CONSUMPTION AND IRON-DEFICIENCY ANEMIA AMONG PREGNANT WOMAN IN BOGOR DISTRICT, INDONESIA

2019 ◽  
Vol 10 (2) ◽  
pp. 91-100
Author(s):  
Putri Bungsu Machmud ◽  
Ratna Djuwita Hatma ◽  
Ahmad Syafiq
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Serum Ferritin ◽  
Iron Status ◽  
Demographic Data ◽  
Secondary Data ◽  
Deficiency Anemia ◽  
Tea Consumption ◽  
Cross Sectional

Background. Anemia in pregnancy is an essential problem due to affect to not only the mother’s life but also to baby’s life. An iron deficiency causes about 75 percent of anemia during pregnancy. Objective. This study aimed to identify risk factors for iron deficiency among pregnant women and determine the possible link between iron status and tannin levels associated with tea consumption. Method. The population-based cross-sectional studies were conducted from secondary data of previous thesis-research in 2013, “Pengaruh Kadar Tanin pada Teh Celup terhadap Anemia Gizi Besi (AGB) pada Ibu Hamil di UPT Puskesmas Citeureup Kabupaten Bogor Tahun 2012”. The study population consisted of 94 randomly selected pregnant women. The inclusion criteria were pregnant women who participated in the previous study and have a complete antenatal care record. Demographic data were collected, including data on age, working status, gestational stage, time since last pregnancy, and parity. The information included nutritional variables, such as iron supplements, nutritional status, and iron intake. Also, data for tannin level grouped as low, medium, and high based on the frequency of daily tea consumption and tea-making habits. The linear model analysis was used to determine the influence of tea consumption on serum ferritin levels. Results. The results showed that time since last pregnancy (<2 years), parity (more than two children), reduced consumption of foods containing heme, and levels of tannin consumption (low, medium, or high) were predictors of iron-deficiency anemia. The results also suggested that tannin levels were inversely proportional to serum ferritin levels. Conclusion. Pregnant women who consumed tea with a low tannin level had the highest serum ferritin levels, whereas those who drank tea with medium and high tannin levels had the lowest serum ferritin levels.

scholarly journals Association between Serum Ferritin and Pre-eclampsia

2019 ◽  
Vol 47 (3) ◽  
pp. 18-24
Author(s):  
Ratna Paul ◽  
Mst Sabrina Moonajilin ◽  
Sujit Kumar Sarker ◽  
Himel Paul ◽  
Swapna Pal ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Serum Ferritin ◽  
Serum Ferritin Level ◽  
Ferritin Level ◽  
Deficiency Anemia ◽  
Control Group ◽  
The Mean

Pre-eclampsia (PE) is a major cause of maternal and prenatal morbidity and mortality in developing countries. PE occurs in about 6% of the general women population. It complicates about 5-15% of pregnancies over 20 weeks and is responsible for 16% of maternal mortality. Pre-delivery serum Ferritin concentration was significantly higher in patients with eclampsia than in healthy pregnant women. The serum ferritin was the best sensitive marker of the iron status parameters reflecting the preeclampsia. The aim of the study is to explore the association between serum ferritin and Preeclampsia and to do a comparison of serum ferritin to assess risk of development preeclampsia between case and control.This is a case-control study with laboratory methods. The study was carried out in Sir Salimullah Medical College and Hospital. Serum Ferritin was tested in the department of biochemistry, Bangabandhu Sheikh Mujib Medical University (BSMMU). The study was carried out from January 2008 to December 2009 and the sample size was 80. A total of 80 pregnant women, comprising of 40 PE and 40 normotensive primi or multigravida in the third trimester were enrolled in the study. The mean Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) were significantly higher in PE group on both occasions compared to normotensive women with similar chronological age gestational age. Out of the 40 cases 65% patients had severe proteinuria (+++) and 17.5% had moderate proteinuria (++) and 17.5% had mild proteinuria. The difference between case and control with respect to proteinuria was highly significant. More than two third (67.5%) of the cases did not have any iron deficiency anemia, while the rest (32.5%) had mild iron deficiency anemia. In the present study, the mean serum Ferritin level of PE group was almost 10 times higher (167.11 ± 10.43 ngm/ml) than that of controls (17.0 ± 3.03 ngm/ml) than that of control (431.0 ± 10.93 gm/dl). More than one-third of the cases showed serum ferritin >210 ngm/ml, compared to none of the control group. Serum Ferritin level is significantly higher in preeclamptic patients than the control group. Bangladesh Med J. 2018 Jan; 47 (3): 18-24

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