scholarly journals Expression Levels of Some Detoxification Genes in Liver and Testis of Rats Exposed to a Single Dose of Methyl-Tertiary Butyl Ether

2016 ◽  
Vol 4 (2) ◽  
pp. 232-235 ◽  
Author(s):  
Ahmad Ali Badr ◽  
Mostafa Saadat
Keyword(s):  
Single Dose ◽  
Peanut Oil ◽  
Methyl Tertiary Butyl Ether ◽  
Mrna Levels ◽  
Butyl Ether ◽  
Tertiary Butyl ◽  
Antioxidant Genes ◽  
Short Term Exposure ◽  
Metabolism Enzymes ◽  
Significant Difference

AIM: Methyl-tertiary-butyl ether (MTBE), a well-known gasoline oxygenate compound, is still used in several countries. Several studies investigated the effects of MTBE on the activity of phase II metabolism enzymes. There is no published data on the effect(s) of short-term exposure to MTBE on mRNA levels of antioxidant genes. Therefore, the present study was carried out.METHODS: A total of 15 adults male Wistar rats were randomly divided into five equal experimental groups. They received a single dose of 0, 400, 800 and 1600 mg/Kg MTBE in peanut oil by gavages. The final group received no MTBE and peanut oil. After 24 hr animals were slaughtered then livers and testis were removed to extract the total RNA. Real-time PCR was done to detect the gene expressions of glutathione S-transferase family (Gstt1, Gstm1, and Gstp1). RESULTS: The mRNAs levels of the examined genes neither in liver nor in testis showed a significant difference between the exposed groups and control rats.CONCLUSIONS: The present data revealed that exposure to a single dose of MTBE has no significant effect on the mRNA levels of the Gstt1, Gstm1, and Gstp1 genes.

APPLICATION OF IR SPECTROSCOPY IN THE STUDY OF MINERAL OIL

2017 ◽  
pp. 91-95
Author(s):  
E. I. Grushova ◽  
A. .. Al Razuqi ◽  
E. S. Chaiko ◽  
O. A. Miloserdova
Keyword(s):  
Ir Spectroscopy ◽  
Group Composition ◽  
Mineral Oil ◽  
Vacuum Distillate ◽  
Methyl Tertiary Butyl Ether ◽  
Butyl Ether ◽  
Tertiary Butyl ◽  
Mineral Oils ◽  
Modifying Additive

IR spectroscopy investigated structural and group composition of base mineral oils isolated from the vacuum distillate by selective purification of N-methylpyrrolidone and the low temperature dewaxing in the presence of a solvent. The role of the latter was carried out by the systems acetone - toluene, acetone - methyl tertiary butyl ether, methyl ethyl ketone - toluene, acetone - toluene - modifying additive. It was shown that the chemical composition of the group of base oils and slack waxes is defined as the nature of the solvent to the dewaxing, and oils sequence of purification steps.

The Effect of Adding Oxygenated Compounds to Gasoline on Automotive Exhaust Emissions

2002 ◽  
Vol 125 (1) ◽  
pp. 344-350 ◽  
Author(s):  
S. G. Poulopoulos ◽  
C. J. Philippopoulos
Keyword(s):  
Octane Number ◽  
Combustion Engine ◽  
Methyl Tertiary Butyl Ether ◽  
Butyl Ether ◽  
Tertiary Butyl ◽  
Research Octane Number ◽  
Oxygenated Compounds ◽  
Reid Vapor Pressure ◽  
Three Way Catalyst ◽  
Unregulated Emissions

In the present work, the effect of adding ethanol or methyl tertiary butyl ether (MTBE) to gasoline on the regulated and unregulated emissions from an internal combustion engine with a typical three-way catalyst was studied. The addition of ethanol to fuel (10% w/w) increased both the research octane number and the Reid vapor pressure of the fuel, whereas adding 11% w/w MTBE caused an increase only in the research octane number of the fuel. When the fuel contained MTBE, less hydrocarbons, carbon monoxide, and acetaldehyde were emitted in the tailpipe. The increased emissions of acetaldehyde and ethanol were the main disadvantages of using ethanol.

Methyl tertiary-butyl ether mode of action for cancer endpoints in rodents

2007 ◽  
Vol 47 (2) ◽  
pp. 156-165 ◽  
Author(s):  
George Cruzan ◽  
Susan J. Borghoff ◽  
Ann de Peyster ◽  
Gordon C. Hard ◽  
Michael McClain ◽  
...  
Keyword(s):  
Mode Of Action ◽  
Methyl Tertiary Butyl Ether ◽  
Butyl Ether ◽  
Tertiary Butyl

Simulation of Methyl Tertiary Butyl Ether Production in Catalytic Distillation

2012 ◽  
Vol 263-266 ◽  
pp. 444-447
Author(s):  
Jin Nan Chen ◽  
Yu Chun Zhang ◽  
Xing Yong Sun
Keyword(s):  
Relative Error ◽  
Conversion Rate ◽  
Model Development ◽  
Methyl Tertiary Butyl Ether ◽  
Reflux Ratio ◽  
Distillation Process ◽  
Butyl Ether ◽  
Catalytic Distillation ◽  
Design Data ◽  
Tertiary Butyl

The software of the catalytic distillation process of methyl tertiary butyl ether was developed by using Process Simulation System Platform. The isobutylene conversion rate was calculated by using the catalytic distillation software. The relative error of isobutylene conversion rate between the simulation results and the design data from the China Petroleum Hohhot Petrochemical Co. was less than 5%. The relative error satisfies industrial design requirements. At present, enterprise workers use this software to learn how to operate the catalytic distillation process. The catalytic distillation software is further used to study the influence of reaction temperature and reflux ratio on the isobutylene conversion rate which can be used for future empirical model development and control studies.

Estimation of Respiratory Irritancy from Inhaled Methyl Tertiary Butyl Ether in Mice

1994 ◽  
Vol 6 (6) ◽  
pp. 563-569 ◽  
Author(s):  
Jeffrey S. Tepper ◽  
Mette C. Jackson ◽  
John K. McGee ◽  
D. L. Costa ◽  
J. A. Graham
Keyword(s):  
Methyl Tertiary Butyl Ether ◽  
Butyl Ether ◽  
Tertiary Butyl

Two-generation Reproductive Toxicity Study of Methyl Tertiary-butyl Ether (MTBE) in Rats

1997 ◽  
Vol 17 (S1) ◽  
pp. S13-S19 ◽  
Author(s):  
C. Bevan ◽  
T. L. Neeper-Bradley ◽  
R. W. Tyl ◽  
L. C. Fisher ◽  
R. D. Panson ◽  
...  
Keyword(s):  
Reproductive Toxicity ◽  
Toxicity Study ◽  
Methyl Tertiary Butyl Ether ◽  
Butyl Ether ◽  
Tertiary Butyl
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