scholarly journals Clinical Therapeutic Effects of the Application of Doxycycline in the Treatment of Periodontal Disease

2016 ◽  
Vol 4 (1) ◽  
pp. 152-157 ◽  
Author(s):  
Spiro Spasovski ◽  
Zlatanka Belazelkoska ◽  
Mirjana Popovska ◽  
Aneta Atanasovska-Stojanovska ◽  
Vera Radojkova-Nikolovska ◽  
...  

OBJECTIVE: To compare the therapeutic effects of the application of doxycycline-full dose (100 mg) and sub-dose (20 mg) in the treatment of periodontal disease.MATERIAL AND METHODS: A total of 60 patients with periodontal disease were examined. Patients are divided into two groups: A) treated with antimicrobial dose of 100 mg doxycycline once daily for 30 days, and B) treated with 2 x 20 mg/day. doxycycline, during 75 days. Among all patients a conservative treatment was carried out and ordinated the proper dose doxycycline in total dose during treatment from 3 gr. Index of dental plaque by Löe-Sillness, index of gingival inflammation and gingival bleeding by Cowell were followed.RESULTS: Values of dental plaque in relation first examination, 10th, 20th day, 1 month and 2.5 months, showed that after 2.5 months, average value (x = 0.83) of dental plaque in second group is slightly less than the value (x = 0.93) of dental plaque in the first group. The average value (x = 0.17) of gingival inflammation in second group is significantly less than the value (x = 0.50) of gingival inflammation in the first group. The average value (x = 0.97) of gingival bleeding in patients from the first group was significantly higher than value(x = 0.37) of gingival bleeding in the second group.CONCLUSION: Patients whose therapy was helped by a sub-dose doxycycline demonstrated positive therapeutic effects on gingival inflammation and bleeding.

Author(s):  
Surbhi Porwal ◽  
Aditi Mathur ◽  
Neema Shetty ◽  
Balaji Manohar ◽  
Barkha Makhijani ◽  
...  

Background: Plaque is the soft deposit that forms the biofilm consisting of microorganisms adhering to the tooth surface and is proved beyond doubt to be the initiator of gingival and periodontal disease. Plaque control is the mainstay in periodontal disease. Aim: To compare the effect of 0.2% chlorhexidine gluconate, raw propolis and 3% hydrogen peroxide mouthwash on dental plaque and gingival inflammation. Materials and Methods: Thirty subjects in the age group of 20-40 years were enrolled in the study. Plaque index and Modified Gingival Index were recorded at baseline and oral prophylaxis was performed. Subjects were then randomly divided into three groups (n=10) and were asked to rinse with 10ml mouthwash twice daily for 15 days. Group I received 0.2% chlorhexidine gluconate mouth wash, Group II raw propolis diluted with distilled water (1:1), and Group III 3% hydrogen peroxide (1:1) mouthwash. Subjects were recalled on 7 day and 28 day for re-evaluation and recording plaque index and modified gingival index. Statistical analysis was done to evaluate the efficacy of all the three mouthwashes. Results: The results showed that all the three mouthwashes were effective in reducing plaque and gingival inflammation. Chlorhexidine gluconate 0.2% showed to be the most effective in reduction of dental plaque. Propolis was observed to be the most effective in reducing gingival inflammation over a period of 28 days. Conclusion: Propolis can be effectively used as a mouthwash without any potential side effects as an alternative to chlorhexidine mouthwash in reducing gingival inflammation.


Author(s):  
Ilma Robo

The treatment of periodontal diseases, mainly of their origin, with the most common clinical manifestation in form of gingival inflammation, is manifold and powerful, including: mechanical therapy, antibiotic, antiseptic and various approaches to treatment, which are recommended to be used within a short period of time. New therapeutic approaches have been proven as alternative treatment to conventional therapy, or in combination with conventional therapies, to reduce the number of periodontopathic pathogens in gingival sulcus. HBOT has a detrimental effect on periodontal microorganisms, as well as beneficial effects on the healing of periodontal tissue, increasing oxygen pressure in gingival pockets. Our study is aimed at reviewing the current published literature on hyperbaric oxygen therapy and focuses on role of HBOT as a therapeutic measure for the individual with periodontal disease in general and for the impact on the recovery of gingival inflammation. HBOT and periodontal treatment together, reduce up to 99% of the gram-negative anaerobic load of subgingival flora. HBOT, significantly reduces subgingival anaerobic flora. Clinical effects in 2-year follow-up of treated patients are sensitive. Reduction of gingival hemorrhage indexes, depth of peritoneum, plaque index, occurs in cases of combination of HBOT and detraction. Reduced load persists up to 2 months after therapy. The significant increase in connective tissue removal starts at the end of 2nd week, to achieve the maximum in week 3-6 of application. HBOT used for re-implantation, stimulates the healing of periodontal membrane, pulp, prevents root resorption, healing of periodontal lining tissues. HBOT, significantly reduces the hemorrhage index with 1.2 value difference, 0.7mm probe depth, reduces gingival fluid by 2. HGH exposure is increased by gingival blood flow, with a difference of 2 in measured value. The therapeutic effects of HBOT in the value of the evaluation index can be saved up to 1-year post treatment.


2018 ◽  
Vol 68 (12) ◽  
pp. 2853-2856 ◽  
Author(s):  
Igor Jelihovschi ◽  
Cristian Drochioi ◽  
Aida Corina Badescu ◽  
Raoul Vasile Lupusoru ◽  
Alexandra Elena Munteanu ◽  
...  

The diagnosis of periodontal disease is mainly based on use of clinical and radiographic evidence. In this study we employed a quantitative PCR analysis of Aggregatibacter actinomycetemcomitans and Treponema denticola as species strongly involved in periodontal diseases, burden in periodontal pockets to detect the main sampling factors that interfere with qPCR results. From 22 patients with advanced periodontal disease, subgingival plaque was comparatively collected by paper points and periodontal Gracey curettes. Samples were collected from the same situs in presence of gingival bleeding and absence of bleeding. The concordance and agreement of results between samples were assessed. The present study demonstrates that subgingival plaque sampling with sterile absorbable paper points is often accompanied by gingival bleeding resulting in quantification biases of periodontal pathogens.


2021 ◽  
Vol 6 (2) ◽  
pp. 13-22
Author(s):  
Azlan Jaafar ◽  
Normaliza AB Malik ◽  
aws hashim ali alkadhim

Objective: To identify the prevalence of caries, plaque score, and periodontal disease and explore the correlations between oral health literacy scores and oral health status among undergraduate students. Materials and Methods: A cross-sectional study was conducted with a group of undergraduate students using the Malay version of the Oral Health Literacy (OHL) Index. A stratified random sampling technique was used to select the samples. Clinical oral examinations were conducted by a single trained examiner using a Community Periodontal Index (CPI) probe and a mouth mirror. Data analysis was conducted using statistical tests contained in SPSS version 26, and statistical significance was set at p<0.05. Results: A total of 280 students were recruited into the study. The prevalence of caries and periodontal disease was 58.9 and 13.2%, respectively. There was a significant association between OHL and field of study (p<0.001). There was also a significant negative but weak correlation between OHL and dental plaque scores (r= -0.147; p=0.014). A significant positive but weak correlation was found between dental plaque scores and dental caries (r= 0.135; p=0.024) and periodontal pocket depth (r= 0.168; p=0.005). Conclusion: The prevalence of dental caries was high, while the prevalence of periodontal diseases was low in this study. OHL correlated significantly with dental plaque scores and field of the study. Thus, OHL assessment is essential to understand a person’s OHL levels and can be considered a screening tool for early detection of poor oral hygiene.


2021 ◽  
Vol 33 (3) ◽  
pp. 217
Author(s):  
Maria Efrinta Ginting ◽  
Rosiliwati Wihardja ◽  
Dyah Nindita Carolina

Introduction: Bronchial asthma patients use inhalation drugs as therapy to achieve a controlled asthma state. Inhaled corticosteroids and β2 agonists are the medication that is being used in this case. Prolonged use of inhalation drugs will affect the health of periodontal tissue. The effect of these drugs can reduce the periodontal defense mechanism and increase the risk of periodontal disease. This study aims to determine the periodontal clinical features of bronchial asthma patients using inhalation drugs. Method: This research was a descriptive study. The sample of the study were 22 females and 8 males bronchial asthma patients at the Community Lung Health Center of Bandung (Balai Besar Kesehatan Paru Masyarakat Bandung/BBKPM Bandung) who had been using inhalation drugs for at least one year. The periodontal clinical feature was assessed by employing a Community Periodontal Index (CPI) modified with probing the gingival sulcus to assess the presence of gingival bleeding, periodontal pocket, and loss of clinical attachment where then a periodontal status was obtained. The periodontal status data were then processed using the periodontitis case definitions from the Centers for Disease Control and Prevention/American Academy of Periodontology (CDC/AAP) to determine periodontal disease in asthmatics patients. Results: Clinical features of gingival bleeding were found in 26 asthmatic patients (86.7%), periodontal pockets in 18 asthmatic patients (60%), and loss of clinical attachment in 27 asthmatic patients (90%). Based on the CDC/AAP case definition, 23 asthmatic patients (76.7%) had periodontitis. Bronchial asthma patients who used inhalation drugs had a risk of periodontitis.Conclusion: Bronchial asthma patients who used inhalation drugs for at least one year had gingival bleeding and loss of clinical attachment and periodontal pocket.


2009 ◽  
Vol 137 (1-2) ◽  
pp. 6-9 ◽  
Author(s):  
Obrad Zelic ◽  
Sasa Cakic ◽  
Natalija Lukovic

Introduction. Since the discovery that periodontal diseases are caused by microbial plaque the interest of many scientists has been focused on oral antiseptics. There are very few mouthrinses with oral antiseptic effect originally designed in our country. One of these is Ozosept? solution. Objective. This study evaluated the effect of Ozosept? solution (phenol compound) on the oral hygiene and gingival inflammation, in comparison with Hibidex DAP? solution (chlorhexidine digluconate). Methods. Two groups, each of 21 persons, which did not significantly differ concerning Silness-L?e plaque index (PI) and L?e-Sillnes gingival index (GI), used one of the studied oral antiseptic for a 15-day period. Oral hygiene was maintained by subjects' habitual home methods, and no technique of professionally advised brushing was performed during the experimental period. Results. At the end of the study, PI and GI scores were lowered to a statistically high significance in both groups of participants in comparison to the indexes at the beginning of the study. At the end of the study, PI and GI scores did not significantly differ between the two analyzed groups. No side effects, which were recorded in the Hibidex DAP? group (tooth and filling staining 9.5% and 4.74% respectively, transitory tongue numbness 28.6% and reduced taste sensation 14.3%), were registered in the group of subjects using Ozosept? solution. Conclusion. It is concluded that Ozosept? solution is effective in the control of dental plaque - biofilm accumulation and gingival inflammation, and produces no side effects related to chlorhexidine digluconate usage.


2013 ◽  
Vol 14 (4) ◽  
pp. 731-737 ◽  
Author(s):  
Reem Saleem Tubaishat ◽  
Zain A Malkawi ◽  
Zakereyya S Albashaireh

ABSTRACT Aim The aim of this study to determine the influence of smoking on self-reported oral health status among university students. Materials and methods Voluntary sample of 669 adults of 18 to 26 years old were invited to participate in the study. They were asked to read a self-designated questionnaire and a covering letter which explained the purpose of the study. The questionnaire addressed self-reported demographics, oral hygiene and smoking habits; knowledge about smoking and its effects on oral health. Data were statistically analyzed using Chi-square test to determine statistically significant differences across the oral health status. Results The sample included 340 (56.7%) males and 240 (43.3%) females; 56.8% of the subjects were nonsmokers; 43.2% were current smokers, and 17.5% smoke argileh. Almost 24.7% of subjects started smoking because of emotional effects; 66.9% did not smoke because of its harm to health. The percentage of subjects with dental plaque on their teeth was 27.1%, and with calculus was 27.9%, and with stains was 26.9%. About 35.5% of the subjects brushed their teeth once daily. Statistically, significant association was proven between smoking and gender (p < 0.01); and smoking and halitosis (p < 0.01). Conclusion Smoking is significantly related to esthetics, calculus, tooth stains, halitosis, gingival bleeding, and gender with p < 0.01, p < 0.01, p < 0.01, p < 0.01, p = 0.05, and p < 0.01 respectively. How to cite this article Tubaishat RS, Malkawi ZA, Albashaireh ZS. The Influence of Different Factors on the Oral Health Status of Smoking and Nonsmoking Adults. J Contemp Dent Pract 2013;14(4):731-737.


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