scholarly journals The relationship between brucellosis and vitamin D

2016 ◽  
Vol 10 (02) ◽  
pp. 176-182 ◽  
Author(s):  
Behice Kurtaran ◽  
Ozay Akyildiz ◽  
Aslihan Candevir Ulu ◽  
Seza Ayse Inal ◽  
Suheyla Komur ◽  
...  

Introduction: This study was aimed to determine the relationship between vitamin D and soluble vitamin D receptor (VDR) levels and brucellosis, a common infection in Turkey, in which the cellular immune system is important in the course of the disease. Methodology: Patients who had been followed up in the Department of Infectious Diseases and Clinical Microbiology of Cukurova University Medical Faculty, having been diagnosed with brucellosis and who had no brucellosis treatment before, were enrolled in the study along with healthy controls. The participants’ vitamin D and soluble VDR values were recorded. Laboratory parameters of patients and controls, clinical findings, and disease course of brucellosis patients were also noted. Results: The mean age of the 86 brucellosis patients, of whom 38 (44.2%) were males and 48 (55.8%) were females, was 40.9 ± 18.4 years. Complicated course of brucellosis rate was found to be 29.1%. Vitamin D and VDR levels were lower in brucellosis patients at the time of diagnosis compared to control group. For males, vitamin D and VDR levels were higher in the control group than in the patient group. In males, VDR levels were higher than in females. A significant difference was not found between clinical forms of the disease and vitamin D and VDR levels. Conclusions: Vitamin D and VDR levels were shown to be significantly lower in brucellosis patients before treatment compared to the control group. These results suggest that vitamin D could be involved in the pathogenesis of the disease.

2019 ◽  
Vol 25 (4) ◽  
pp. 193-199
Author(s):  
Zamfirescu Mihaela ◽  
Ghiță Nicolae-Alexandru ◽  
Chirilă Sergiu ◽  
Gurgaș Leonard ◽  
Hangan Tony

Abstract The Vitamin D deficiency could be involved in the development of psoriasis, Vitamin D defficiency being considerd to be involved in the development of disorders related to cellular immune system. The aim of this study is to review the literature in order to find if there is an association between the Vitamin D level in the serum and psoriasis. A search for relevant articles was performed using PubMed, Web of Science and Springer databases. A total of 19 articles fulfilled the criteria for inclusion in this review. 14 studies revealed statistically significant lower levels of Vitamin D in psoriatic patients when compared to healthy controls. The other 5 studies did not found a statistically significant difference between 25-hydroxycholecalciferol levels in psoriasis group and in control group.


2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Shakil Mahmood ◽  
Matiur Rahman ◽  
Subrata Kumar Biswas ◽  
Shaikh Nazmus Saqueeb ◽  
Shiblee Zaman ◽  
...  

Despite the abundant sunlight, vitamin D deficiency is prevalent in South Asian countries including Bangladesh. Information on vitamin D level is insufficient in adults particularly in female garment workers in Bangladesh. This study was designed to evaluate the status of vitamin D, parathormone (PTH), calcium, and alkaline phosphatase (ALP) among the female garment workers in Bangladesh. Blood samples were collected from female garment workers (n=40, case group) and general female workers (n=40, control group) in Dhaka. Serum vitamin D, PTH, calcium, and ALP were measured by chemiluminescence microparticle immunoassay. The mean level of vitamin D was significantly (p<0.001) lower in case (14.2±2.6 ng/mL) than in the control (22.4±2.4 ng/mL) group. No significant difference was found at mean of PTH and calcium between case (33.9±17.2 pg/mL;9.1±0.6 mg/dL, resp.) and control (35.9±16.3 pg/mL;9.3±0.6 mg/dL, resp.) group. The mean ALP in case (117.2±14.4 U/L) group was significantly (p<0.001) higher than the control group (80.5±30.6 U/L). Overall, PTH level did not show significant correlation with vitamin D. However, calcium and ALP levels showed a significant positive (p<0.05) and negative (p<0.001) correlation with vitamin D, respectively. This study indicates a high prevalence of vitamin D deficiency in the female garment workers in Bangladesh.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
V. Talevska

Aims:To define the importance for the difference between the EEG in patients with criminal behavior and in control group. To examine the relationship between the EEG of the patients with criminal behavior and diagnosis as well as the prompt registration of EEG changes.Material and methods:158 EEG investigations examined at the Psychiatric Hospital in Demir Hisar for 24 months with aggressive and criminal behavior.Results and discussion:In men normal EEG (69.44%) prevails. The means age of patients in examiner group with abnormal EEG is significant higher from the means age in patient's with normal EEG. There was the significant difference between normal and abnormal EEG and the diagnoses. There is not significant difference between the patient's behavior and EEG, and there was significant difference between EEG and its criminal factor. There was not relation between EEG and the patient's sex in control group. The difference between the means age (37.73 god.) in control group with abnormal EEG and the mean age of patients with normal EEG is significant. There was not significant relation between EEG and patient's diagnosis of control group. There was not connection between patient's behavior and EEG in control group. There was significant difference between EEG in examiner group and in control group.Conclusion:There was significant difference between EEG in control and in examiner group.Suggested measures:Easily diagnosis providing of psychiatric disorders with aggressive and criminal behavior with EEG -help and safety measures at examiners with criminal behavior.


2020 ◽  
Vol 5 (1) ◽  
pp. e17-e17
Author(s):  
Arezoo Moradi ◽  
Fatemeh Sharif Zadeh

Introduction: Prevalence of vitamin D deficiency has been reported from all over the world since lower levels of vitamin D has been one of word’s problem in the 21st century; especially pregnant women are the most prominent one. Objectives: This study aims to investigate the relationship between mothers’ vitamin D level with infants’ birth-weight and head circumference. Patients and Methods: A cross-sectional study was conducted in the department of obstetrics and gynecology of Akbarabadi hospital during 2017-2018. Regarding two groups, infants’ three main characteristics including their weight, head circumference and height were studied. Results: The mean blood levels of vitamin D in mothers with normal-born neonates were 15.23 ± 7.14 (ng/ mL) and in the mothers who gave birth to low-birth weight were 10.02 ± 8.06 (ng/mL), which was significantly lower than the mothers of normal-weight infants (P=0.018). The mean blood levels of vitamin D in mothers who gave birth to a normal head circumference neonate were 16.07 ± 8.1 (ng/mL) and in mothers with infants’ head circumference of less than 33 cm, was 9.87 ± 7.57 (ng/mL), which was significantly lower from mothers of normal-head circumference infants (P=0.007). The serum levels of vitamin D in mothers with normal-height infants were 14.74 ± 7.52 (ng/mL) and in the mothers with a height of less than 47 cm were 15.17 ± 7.91 (ng/mL), that does not suggest any significant difference (P=0.341). The mean serum vitamin D level in mothers who had normal vaginal delivery was lower than those with cesarean delivery, however there was no significant difference (P=0.174). Conclusion: Nutrition improvement and prescribing vitamin D supplements can positively be effective in the way of curbing low-birth weight infants. Moreover, Exposure to sunlight and letting rays strike skin is essential for maintaining a healthy vitamin D status for girls and women.


2010 ◽  
Vol 22 (1) ◽  
pp. 178 ◽  
Author(s):  
S. Scolari ◽  
R. Evans ◽  
R. Knox ◽  
M. Tamassia ◽  
S. Clark

Accurate estrus detection is an essential component of a successful AI program in modern swine operations. It is necessary to establish efficacious means of estrus detection and optimize reproductive performance in the herd. Measurement of physiological traits such as body temperature, vaginal electrical resistance, and vulva reddening have been investigated as methods to aid in estrus detection in swine. The relationship between vulvar skin temperature (VST) and ovulation has not been previously investigated. Therefore, the objective of this study was to assess changes in VST that occur during the periovulatory period using digital infrared thermography (IRT). The experiment group consisted of a total of 25 gilts and 27 multiparous sows, and the control group consisted of 30 sows that were 60 days of gestation. All Yorkshire-Landrace females were housed individually in a temperature and humidity controlled environment. VST were measured twice daily at 8-h intervals using the infrared digital thermocamera (Fluke IR FlexCam® Thermal Imager, Fluke Corporation, Everett, WA) while the animals were standing and eating prior to estrus detection. Estrus detection was performed twice daily (at 8-h intervals) with the aid of an adult boar. Once standing estrus was observed, transrectal real-time ultrasound was performed twice daily at 8-h intervals to monitor follicle development and determine the time of ovulation. Ovaries were visualized using an Aloka 500 V ultrasonics machine (Aloka Inc., Tokyo, Japan) fitted with a transrectal 7.5-MHz linear transducer, which was fitted into a rigid, fixed-angle PVC adapter. Average VST and hours were reported in mean ± SEM and compared using an ANOVA and Student’s t-test using SAS software (SAS Institute Inc., Cary, NC, USA). Additionally, pairwise comparisons were performed to compare VST at different times during estrus. Significant differences were reported at P ≤ 0.05. Evidence of CL formation and ovulation was detected at 38 ± 9.3 h after onset of estrus in gilts, and 43 ± 12 h in sows. The mean VST of sows during estrus was significantly higher (P ≤ 0.05) than that of gilts. During estrus, the mean VST of gilts reached a peak of 35.6 ± 0.24°C and then decreased significantly to 33.9 ± 0.32°C 12 h prior to ovulation. This marked change in mean VST was detected between 36 and 12 h prior to ovulation. There was a similar trend in sows with a peak mean VST of 36.1 ± 0.25°C at 24 h prior to ovulation and then dropping to 34.6 ± 0.31°C 12 h prior to ovulation. There was no significant difference (P ≥ 0.05) between VST in gilts and sows at the time of ovulation. This study demonstrated that VST of sows and gilts measured by IRT change significantly during the periovulatory period. Additionally, there are distinct times that VST rises and then falls precipitously in sows compared with gilts. Digital IRT as a predictor for ovulation in swine appears to be a promising tool. Further studies involving predictor models and hormonal assays need to be performed.


Author(s):  
Hanieh Mollazadeh ◽  
◽  
Surena Nazarbaghi ◽  
Mohammad Reza Pashaei ◽  
◽  
...  

Objective: Celiac disease can be associated with other diseases, including neurological disorders. In this study, the relationship between celiac disease and refractory epilepsy was evaluated in patients referred to Imam Khomeini Hospital of Urmia. Material & Methods: In this cross-sectional study, patients with refractory epilepsy referred to the neurology clinic of Imam Khomeini Hospital of Urmia, during the second half of 2019 and controlled epilepsy were studied as a control group. The statistical population of the present study included 50 patients with refractory seizures and 50 patients with controlled seizures. The mean age of patients was 32.96 ± 11.35 years. Five ml blood samples were taken from the patients, and a serum anti-tTG test was performed using the ELISA kit. Then, in patients with positive anti-tTG, a duodenal biopsy sample was prepared using an endoscopy. Results: This study showed that the mean serum level of anti-tTG in patients with refractory epilepsy was higher than in patients with controlled epilepsy. Anti-tTG test results were positive in five of fifty patients with refractory epilepsy, and it was positive in two of fifty patients with controlled epilepsy. There was no significant difference between the two groups in terms of serum levels anti-tTG (p=0.14). Also, there was no significant relationship between serum level anti-tTG, age and genus (p>0.05). Biopsy results in three patients in the refractory epilepsy group and one patient in the controlled epilepsy group was in favor of a definitive diagnosis of the celiac disease. Patients in whom the celiac disease was confirmed by endoscopy had higher anti-tTG levels (p=0.006). Conclusion: There was no significant difference between the celiac disease in the group with refractory epilepsy and controlled epilepsy.


2020 ◽  
Vol 15 (4) ◽  
pp. 166-178
Author(s):  
Nilüfer Bulut ◽  
Mehmet Çağatay Taşkapan ◽  
Hülya Taşkapan

It is suggested that a number of environmental and genetic factors trigger the formation of progressive kidney damage and complications. One of these factors is inflammation, it occurs as a result of a series of mechanisms included within a number of cytokines. Vitamin-D, IL-6, PCT and hs-CRP are also valuable biomarkers in terms of mortality in dialysis patients in this sense. Vitamin D deficiency is common in patients with chronic kidney disease (CKD) and is associated with inflammation. In recent years, some randomized controlled trials have revealed the effect of Vitamin D on inflammation in CKD patients, but the results are conflicting. The aim of this study is to investigate the relationship between Vitamin D, high-sensitivity C Reactive Protein (hs-CRP), procalcitonin and IL-6, and to evaluate the relation of Vitamin D levels with inflammation in PD patients, HD patients and controls. This study was carried on with 40 patients receiving on hemodialysis treatment, 40 patients receiving peritoneal treatment with renal failure disease and with a control group consisting of 40 healthy individuals. Vitamin D levels were measured by HPLC, PCT and IL-6 levels were measured by chemiluminescent method, hs-CRP is measured by nephelometric method. For Vitamin D, there was no differences between the groups. For PCT, there was a significant difference between all groups. For IL-6, while there was no difference between peritoneal and hemodialysis groups, a significant difference was determined between the peritoneal dialysis and control groups. For hs-CRP, there was a significant difference among all groups. While correlation was found between serum PCT levels with IL-6 and hs-CRP, no correlations were found between serum PCT with Vitamin D levels. Although a correlation was found between serum IL-6 levels and hs-CRP, no correlation was detected between serum IL-6 and Vitamin D levels. No correlations were detected between Vitamin D andPCT, IL-6 and hs-CRP.


2019 ◽  
Vol 19 (2) ◽  
pp. 166-170 ◽  
Author(s):  
Seyhan Dikci ◽  
Emrah Öztürk ◽  
Penpe G. Fırat ◽  
Turgut Yılmaz ◽  
Mehmet Ç. Taşkapan ◽  
...  

Objective: To investigate whether serum vitamin D levels have an effect on pseudoexfoliation (PEX) glaucoma/syndrome development and on the control of glaucoma in these cases. </P><P> Method: A total of 31 cases with PEX glaucoma, 34 cases with the PEX syndrome and 43 control subjects of similar age and sex were included in the study. Vitamin D levels were compared between the groups and also between the cases where glaucoma surgery was performed or not. Results: PEX glaucoma group consisted of 17 males and 14 females, PEX syndrome group of 27 males and 7 females, and the control group of 27 males and 16 females. The mean age was 70.9±8.9 years, 72.1±7.3 years, and 67.9±9.1 years in PEX glaucoma, syndrome and control group, respectively. Mean vitamin D levels were 9.4±7.7 ng/mL, 7.9±6,1 ng/mL, 11.5±14.2 ng/mL in PEX glaucoma, syndrome and control group, respectively (p>0.05). The mean serum vitamin D level was 8.04±4.7 ng/mL in those who underwent glaucoma surgery and 10.1±8.7 ng/mL in those who didn't undergo glaucoma surgery in PEX glaucoma group (p>0.05). No difference was found between the PEX glaucoma subgroups in terms of the mean deviation when classified according to vitamin D levels (<10 ng/mL, ≥10 ng/mL) (p>0.05). Conclusion: Although we found no statistically significant difference between the PEX syndrome/ glaucoma, and control group in terms of serum vitamin D levels, serum vitamin D levels were lower in PEX syndrome and glaucoma group than control group. Our results indicate that serum vitamin D levels have no effect on the development of PEX glaucoma/syndrome or the control of the disorder in cases with PEX glaucoma. However, these results need to be supported with further studies on a larger number of patients and with longer follow-up.


2018 ◽  
Vol 12 (1) ◽  
pp. 1012-1020 ◽  
Author(s):  
Atsutoshi Hirata ◽  
Seiya Kato ◽  
Acing Habibie Mude ◽  
Kazuhiro Oki ◽  
Tadashi Matsunaga ◽  
...  

Background and Objective: The relationship between periodontal sensation and Myofascial Pain (MP) is not yet fully clarified. The aim of this study was to test the null hypothesis that there is no difference in the periodontal sensation threshold between subjects with MP and subjects with no Temporomandibular Disorders (TMD). Methods: Participants have clinically assessed in accordance with the Research Diagnostic Criteria for Temporomandibular Disorders version 1.0 guidelines and assigned to the MP group (mean age 54.8 ± 14.8 years; 1 male and 11 females) or the control group (mean age: 63.9 ± 13.2 years; 1 male and 15 females). The Passive Periodontal Sensation Threshold (PPST) was evaluated using impulsive mechanical stimulation on the occlusal surface parallel to the tooth axis of the maxillary first molar, if present. The difference in the mean PPST between the MP group and the control group was evaluated using the Student t-test after checking for homoscedasticity. Results: The mean PPST value was 1050.1 ± 480.3 mN in the MP group and 712.3 ± 288.5 mN in the control group. A significant difference was observed between these mean PPST values (p = 0.045). Conclusion: There was a significant difference in PPST between the MP group and the control group. Although the etiology of the change of PPST is still unknown, the higher PPST value observed in MP patients suggests that future study on occlusal dysesthesia or occlusal sensation-related pathosis is warranted.


2021 ◽  
Vol 15 (1) ◽  
pp. 135-140
Author(s):  
Gülbün Asuman Yüksel ◽  
Gizem Gürsoy

Aim of the study: Parkinson’s disease is the second most common neurodegenerative disorder. The present study investigates the role of vitamin D deficiency thought to be one of the etiopathological and modifying factors in Parkinson’s disease that is known to be multifactorial. Materials and Methods: Designed as a retrospective review of medical records, this study compares the serum vitamin D levels of the idiopathic Parkinson’s disease patients with and without dementia to those of the healthy individuals with no metabolic/degenerative disorders. It also investigates the relationship between the patients’ Standardized Mini-Mental State Examination (SMMSE) and the Unified Parkinson’s Disease Rating Scale (UPDRS) scores and serum vitamin D levels to show the effects of vitamin D on motor symptoms and cognitive functions. Results: In this study, we compared the serum vitamin D levels of 40 Parkinson’s disease patients and 15 Parkinson’s disease patients with dementia to those of the control group comprising 30 healthy individuals. Vitamin D levels were 21,4±15,9 ng/mL in the control group; 16,5±6,4 ng/mL in Parkinson’s disease patients and 13,8±4,5 ng/mL in Parkinson’s disease patients with dementia. All the patient groups had significantly lower vitamin D levels than the control group (p<0,005). Within the Parkinson’s disease group, furthermore, the dementia group had lower vitamin D levels than the non-dementia group. Having examined the relationship between the SMMSE scores and serum vitamin D levels, we found a significant difference in the Parkinson’s disease dementia group (p: 0,020), as well as a relationship of 59,4% in the same direction. On the other hand, there was no significant difference in either patient group in the scores of UPDRS evaluating clinical disability. Conclusion: Consistent with the literature, the present study found that people with Parkinson’s disease had lower mean values of serum vitamin D levels than the control group and showed that serum vitamin D levels were correlated with the cognitive performance. However, the study could not find a relationship between the serum vitamin D levels and the motor performance.


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