scholarly journals Prevalence of bacterial contamination in blood and blood products at the National Blood Service Zimbabwe

2015 ◽  
Vol 9 (04) ◽  
pp. 421-424 ◽  
Author(s):  
Ngonidzashe Makuni ◽  
Clifford Simango ◽  
Rooyen T Mavenyengwa

Introduction: Advances in screening for infections improve the safety of donated blood. Transfusion-related bacterial sepsis, although not established in Zimbabwe, stills makes bacterial contamination of blood clinically relevant. Methodology: This cross-sectional study was conducted in Harare. Bacteriological and antibiotic susceptibility testing were done using standard methods. Results: Of the 196 samples analyzed, 6 (3.1%) were contaminated with bacteria. Platelets had a significantly high contamination rate compared to other blood products. Bacteria showed varying patterns of susceptibility to the antibiotics tested. Conclusions: The prevalence of bacterial contamination in blood products suggests that patients who receive blood products are at risk of developing infection.

2014 ◽  
Vol 7 (6) ◽  
pp. 542-546 ◽  
Author(s):  
Thomas Pepper ◽  
Georgina Hicks ◽  
Stephen Glass ◽  
John Philpott-Howard

Author(s):  
Roshi . ◽  
Vishal R. Tandon

Abstract: Transfusion by blood and blood products forms an important part of treatment. But this is not free from transfusion reactions which may be in the form of fever, rashes, shivering, anaphylaxis or even death. Hemovigilance is a programme of reporting such events.Materials and Methods: The present study was conducted in a tertiary care hospital of Jammu, (J& K). Permission was taken from Institutional Ethics Committee, Govt. Medical College, Jammu. A pretested questionnaire was prepared and circulated among practitioners. They were given time of 15 minutes to fill that questionnaire. After 15 minutes, the filled questionnaire were collected and were analysed. The data was presented in tabulated form.Results: Total 50 practitioners were included in the study. All the practitioners had knowledge about transfusion reactions. Only 10% of the practitioners had knowledge that transfusion reactions can be prevented, 40% of the practitioners had knowledge about hemovigilance programme and had an idea that transfusion reactions can be reported. But only 10% of the practitioners knew where to report and who can report, 6% knew how to report. Only 48% of the practitioners thought that transfusion reactions should be reported, 70% of the practitioners thought that transfusion reactions can be dangerous. 40% of practitioners told that seminars/CMEs should be planned. 80% of practitioners had encountered transfusion reactions, but only 2% had documented the same. 10% of the practitioners had attended seminars, CMEs. Many reasons were quoted for not reporting transfusion reactions.Conclusion:  Overall, most of the practitioners have a positive attitude towards transfusion reaction reporting but knowledge regarding the haemovigilance concept is poor and the majority of them never reported such reaction. Hence, our study demands increased awareness and continued training to strengthen the haemovigilance system.


2020 ◽  
Author(s):  
Ameer Kakaje ◽  
Sabina Mansuor ◽  
Ayham Ghareeb ◽  
Osama Hosam Aldeen

Abstract Introduction Syria has suffered for nine years of war and there were huge demands for blood during and after the lockdown from Coronavirus disease of 2019 (COVID-19).Methods Online questionnaires were distributed to Social Media groups after two weeks of the 10-week full lockdown to determine blood donation patterns. They also included stress, anger, and COVID-19 distress questions.Results The study included 1423 participants, 899 (63.2%) of which were females. Around 48.5% have donated blood, of which 33.3% donated only once in their lifetime. Not having a good reason to donate blood was the main declared reason for not donating, and obtaining a document was the main reason for donating in (64.8%) of participants who had donated blood. Stress, anger, and being distressed to get infected did not have a crucial effect on blood donation, and its patterns. Losing someone close and being endangered from war were associated with more frequent blood donation in contrast to being distressed from war which was more associated with distress from getting infected.Conclusion Distress from COVID-19 was not the main reason for not donating blood. Spreading the culture of volunteer blood donating is crucial as COVID-19 exposure with blood donation can be avoided.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Liliane Siransy ◽  
Sery Romuald Dasse ◽  
Serge Pacôme Dou Gonat ◽  
Antoinette Legbedji ◽  
Koffi N’guessan ◽  
...  

Background. Toxoplasmosis is a widespread cosmopolitan anthropozoonosis, which affects more than a third of the world population. Except the modes of transmission well known,Toxoplasma gondiican be transmitted during transplantation or blood transfusion. The aim of this study is to determine the prevalence of IgG and IgMToxoplasma gondiiand to estimate the potential risk by blood products.Methods. This is a cross-sectional study on the research forToxoplasma gondiiantibodies (IgG and IgM) blood donors performed by ELISA.Results. An overall seroprevalence ofToxoplasma gondiiamong blood donors recruited was 67.92% (n=72). Among these, 68 haveToxoplasma gondiiIgG (64.15%), 12Toxoplasma gondiiIgM (11.32%), and 4 (3.77%) both. The risk varies between 8 for 100000 and 172 for 100000 donations.Conclusion. The need to strengthen security measures for people multitransfused, immunocompromised, and pregnant women to reduce the transmission of toxoplasmosis is important.


2021 ◽  
Vol 15 ◽  
pp. 1-4
Author(s):  
Ali Khazal

Bacterial contamination of donated blood is defined as the presence of bacteria in the blood components which are collected and/or processed for transfusion. It is the second cause of death beyond ABO-mismatch. The aims were to determine the frequency of bacterial contaminations in stored packed RBC and platelet concentrate units. This cross-sectional study was conducted in Baghdad between 2nd of September to 27th of December 2019. Two hundred samples; 100 samples from packed RBC units and 100 samples from platelet concentrate units were randomly selected. There were 38/100 of platelet concentrate units found to be contaminated, while 28/100 samples studied of packed RBC units were contaminated by bacteria. The high rate of contamination of samples presented. Gram-positive bacteria were the most predominant, and this attributed to poor skin cleansing and antiseptic techniques used prior to donor blood collection.


2019 ◽  
Author(s):  
Hilina Motbinor ◽  
Wondemagegn Mulu ◽  
Fetlework Bereded

Abstract Background:Multi-drug resistant(MDR) Acinetobacter baumannii and Pseudomonas aeruginosa are major causes of nosocomial infections globally. They are the current World Health Organization critical priority pathogens for resistance and discovery of new antibiotics. However, there is paucity of data on nosocomial infections caused by such superbugs in Ethiopia.Therfore, this study determined the magnitude and profile of nosocomial MDR Acinetobacter baumannii and Pseudomonas aeruginosa infections among patients hospitalized at Felegehiwot referral hospital, Northwest Ethiopia.Methods:A cross-sectional study was conducted at Felegehiwot referral hospital from April 1 to July 31, 2018.A total of 238 patients presumptive for blood stream, urinary tract and surgical site nosocomial infections were enrolled using convenient sampling technique.Either blood, urine and wound swab specimens were collected and processed using standard bacteriological procedures.A.baumannii and P.aeruginosa isolates were identified using standard bacteriological techniques and confirmed by automated Vitek2 Compact.Antimicrobial susceptibility testing on isolates was performed using the disk diffusion technique.The results interpreted as per the standard zone sizes of Clinical and Laboratory Standards Institute.Chi-square test was done to determine associations among variables.P.value< 0.05 was considered statistical significant. Results:The median age of participants was 29 years.Overall, 20(8.4%) of patients had nosocomial MDR A.baumannii and P.aeruginosa infections.The proportion of nosocomial MDR blood stream, urinary tract and surgical site infections were 13(8.9%),5(8.3%) and 2(6.3%), respectively. The mean age of patients with nosocomial infection was significantly lower (24.9 years) than their counter parts (29.6years) (P=0.035). All isolates of nosocomial infections were from patients with intravenous catheterization.The frequency of nosocomial MDR A.baumannii infection was 9(3.8%) and for P.aeruginosa nosocomial infections was 11(4.6%). A.baumannii and P.aeruginosa isolates were 100% MDR.MDR A.baumannii isolates were 100% resistant to ampicillin and piperacillin.MDR P.aeruginosa isolates was 100% resistant to ampicillin, piperacillin, cefotaxime and ceftriaxone.On the other hand, A.baumannii isolates showed 36.4% and 44.5% resistance against ciprofloxacin and meropenem while P.aeruginosa isolates revealed 33.3% and 45.5% resistance against Pseudomonas aeruginosa.Conclusions:Health care associated MDR A.baumannii and P.aeruginosa infections are critical problems in the study area.Therefore,urgent focused interventions required to contain the spreading of MDR NIs.Treatment of NIs for patients on health care should be guided by antimicrobial susceptibility testing.


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