scholarly journals The impact of herbal remedies on adverse effects and quality of life in HIV-infected individuals on antiretroviral therapy

2010 ◽  
Vol 5 (01) ◽  
pp. 048-053 ◽  
Author(s):  
Nyashadzashe Bepe ◽  
Nathan Madanhi ◽  
Tinashe Mudzviti ◽  
Samuel Gavi ◽  
Charles C Maponga ◽  
...  

Introduction: Use of herbal remedies among HIV-infected individuals in Africa increased in the past decade, mainly due to traditional beliefs and at times inconsistent access to antiretroviral drugs.  In Zimbabwe, accessibility and availability of antiretroviral drugs has increased in recent years; however, the use of herbal remedies remains high.   This study was conducted to determine the impact of concomitant use of herbal remedies with antiretroviral drugs on adverse events and on quality of life. Methodology: A convenient sample of HIV positive patients at Parirenyatwa group of hospitals' Family Care Clinic (Harare, Zimbabwe) was enrolled. A questionnaire was used to collect data on the adverse event experiences of the patients using herbal remedies for their HIV, as well as the types of herbal remedy used. Quality of life index was measured using an HIV/AIDS targeted quality of life (HAT-QOL) tool developed by the World Health Organization. Results:  Abdominal pain (odds ratio = 2.7, p-value = 0.01) and rash (odds ratio = 2.5, p-value = 0.02) had significant associations with using herbal remedies during antiretroviral therapy. Improved quality of life index was not significantly associated with herbal remedy use during antiretroviral therapy. Conclusions:  There is evidence to suggest that some traditional herbal remedies used in Zimbabwe may increase incidence of certain types of adverse events when used in combination with antiretroviral drugs.  Use of herbal drugs in combination with antiretroviral therapy does not significantly improve quality of life index in comparison to antiretroviral drug use only.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e23113-e23113
Author(s):  
Juan Francisco Gonzalez-Guerrero ◽  
Antonia Gloria Alcorta-Garza ◽  
Fernando Alcorta-Nuñez ◽  
Emma María Melgoza-Alcorta ◽  
Melany Gonzalez-Rodriguez ◽  
...  

e23113 Background: Most studies report that tumor related pain occurs between 46% and 92%. The prevalence of pain by clinical stage is 15% in initial stages, 30% in middle stages, 74% in metastatic cancer and, 87% in terminal disease. In the face of chronic diseases such as cancer, patient's relationships with their social networks are affected; among them the interpersonal relationships between the patient and his networks and these towards the patient. With this, the patient’s quality of life is affected. Most of the recent studies on health-related quality of life come from pharmaceutical groups, so it is necessary for other groups to be vigorously involved in the study of the effect of medical interventions on the quality of life, as well as on the impact on health and on the social support of patients with chronic diseases. Methods: In order to obtain the data, validated questionnaires were used as instruments to evaluate the quality of life, measuring psychosocial and health variables, as well as for the detection of the type and quality of psychosocial support perceived by the subjects. The instruments were applied to 207 patients of the Oncology Service of the University Center Against Cancer of the University Hospital “Dr. Jose Eleuterio Gonzalez” in Nuevo Leon, Mexico, during a session of 25 to 30 minutes. Results: Data were collected from 207 patients with chronic oncological pain. The satisfaction index with psychosocial support had a high linear correlation ( r = .640) with the quality of life index. On the other hand, the number of caregivers was not correlated with this last index. Fatigue was the symptom most frequently associated with a decrease in the quality of life index. In addition, pain correlated with all variables except the cognitive index. Conclusions: Satisfaction with the perceived social support is a factor associated with the quality of life in patients with chronic oncological pain; however, the number of caregivers is not. There was no relationship between the size of the network and satisfaction with it. Also, the symptoms associated with chronic oncological pain affect quality of life, identity and social functionality and roles, which in turn impact on the quality of life perceived by patients.


Author(s):  
Yulia V. Agafonova ◽  
Daria L. Simonova ◽  
Sergey N. Simonov

An increase of psoriasis in childhood, a more severe course of this disease, the presence of a cosmetic defect, which causes a negative impact on the quality of life of such patients, determine the relevance of this problem of modern dermatology. Psoriasis is characterized by a psoriatic rash, which is based on hyperkeratosis caused by uncontrollable mitosis of keratinocytes. Despite the recent studies of a large number of various mechanisms that can contribute to the psoriasis development, there is still no clear answer which of them is the main one, and this makes it impossible to achieve in most cases the desired clinical result of treatment, in particular, ensuring stable clinical remission or complete recovery of patients. The purpose of our study was to assess the impact of psoriatic manifestations on the quality of life among children. The object of observation was 106 children aged 4 to 17 years suffering from psoriasis. The average age of the children was 13 years. The measurement was carried out using the “Dermatological Quality of Life Index” (DLQI) (age 16–17 years), and the “Pediatric Dermatological Quality of Life Index” (CDLQI) (age 4–15 years). In addition, we analyze the severity indices of psoriasis in children: BSA, PASI and PGA. As a result of the study, the following was found: in general, psoriasis has a small impact on the quality of life in children – DLQI in children with psoriasis is 5 points; the value of the DLQI index is statistically significantly higher in girls than in boys, and with age the effect on the quality of life in children with psoriasis increases; skin lesions with psoriatic plaques of open areas in children has a significant impact on the quality of life: with scalp psoriasis, the DLQI level is the highest; statistically significant relationships between DLQI and psoriasis severity indices are established: between DLQI and BSA (r = 0.378; p < 0.001), between PASI and DLQI (r = 0.38; p < 0.001). With an increase in the intensity of manifestations of the pathological process assessed by the PGA index, the influence of psoriasis on the quality of life among children also increases (p = 0.011). According to the results of the study, methodological recommendations on medical and social support for children with psoriasis were drawn up and provided to specialized medical organizations.


2021 ◽  
Vol 30 (4) ◽  
pp. 772-780
Author(s):  
Iryna M. Trunina ◽  
Inna V. Khovrak ◽  
Kateryna A. Pryakhina ◽  
Olga P. Usanova

The purpose of the article is to substantiate the methodology for determining the European quality of life index. The theoretical and methodological basis of research is the ideas of the interdependence of life quality and sustainable development. To achieve the desired goal, the following research methods were used: analysis and synthesis (for determining theoretical and practical aspects of ensuring the life quality); statistical (for determining standardized indicators and a European Quality of Life Index for Sweden and Ukraine); abstract-logical (for theoretical summarization and conclusion). As a result, the authors created the European Quality of Life Index based on the comparison of the characteristics of international life quality assessment systems (calculation principle, number and composition of indicators, number of countries covered for calculation), as well as systematization of research by Ukrainian and foreign authors. Therefore, the authors selected twelve main indicators. The indicators are divided into two groups: stimulants (prosperity index, basic human needs index, welfare bases, availability of nutrition and basic health care, GDP per capita, population, global competitiveness index, personal security, access to basic knowledge, ecosystem status) and disincentive (government debt, unemployment). To determine the “European life quality index”, the authors used the formula for calculating the arithmetic mean, as all selected indicators can be considered equivalent as a result of standardization by the method of “minimum- maximum”. In addition, for in-depth analysis, the authors calculated the growth rates of indicators, as well as coefficients of variation. The authors made calculations based on data of 2013–2019 for two countries, namely Sweden and Ukraine. Sweden occupies a much better position in achieving the Sustainable Development Goals, so studying the impact of life quality on sustainable development in this country will suggest ways to achieve the chosen strategic priorities for Ukraine.


Author(s):  
T. Sangeetha ◽  
Raghu M. T. ◽  
Nataraj G. R. ◽  
V. Sharath Kumar ◽  
Y. Satya Krishna ◽  
...  

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">The goal of the study was to assess the prescribing pattern, pattern of skin diseases among the patients and to assess the impact of quality of life in various Skin diseases of dermatological patients by using dermatological quality life index (DLQI). The present study aims at improving the patient’s knowledge towards their disease and medication and also to measure the improvement of Quality of life of patients.</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">A prospective observational study was carried out for a period of six months at Department of Dermatology Basaveshwara Medical College and Hospital, Chitradurga</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Total 150 patients are included. 58 was males and 92 were females. The most skin disease is seen in the age group of 21-40 (40.7%). Majorly skin disease are seen in the illiterate people is (62%), (70.7%) married and 15.3% of socio-economic status of the patients. The major skin disease are seen in the study are psoriasis (12.66%), scabies (16.66%), dermatitis (9.33) and followed by urticaria (6.66%), eczema (4.66%), acne (5.33%). Anti-histamines (16.6%), emollients (9.33%), corticosteroids (9.33%), anti puritics (6.66%), kerotolyte (6.66%) are majorly prescribed drugs. The study showed that there was an extremely significant improvement in DLQI of patients in comparison with first visit result and follow up visit. Whose P value is (&lt;0.001) extremely significant. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Therefore the pharmacist patient education found to have significant influence on improves the patient knowledge towards their disease and medication which shows the positive impact on quality of life among the patients of skin diseases.</span></p>


2009 ◽  
Vol 12 (1) ◽  
pp. 181-184 ◽  
Author(s):  
Gabriel Sandblom ◽  
Per Videhult ◽  
Britt-Marie Karlson ◽  
Staffan Wollert ◽  
Mikael Ljungdahl ◽  
...  

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 16032-16032
Author(s):  
R. Neelam ◽  
C. G. Lis ◽  
D. L. Citrin ◽  
S. Williams ◽  
P. G. Vashi ◽  
...  

16032 Background: Quality of Life (QoL) assessment is important to evaluate the impact of disease and treatment in patients with advanced cancer. Recently, it has been hypothesized that patient satisfaction with their QoL may have a prognostic role in cancer, however, there is little evidence in the literature to support this view. The Ferrans and Powers Quality of Life Index (QLI) is one such instrument. QLI defines QoL as a person’s sense of well-being that stems from satisfaction or dissatisfaction with the areas of life that are important to him/her. The purpose of this study was to determine whether baseline QLI would predict length of survival in patients with colorectal cancer undergoing care in a non-clinical trial setting. Methods: We examined a case series of 177 colorectal cancer patients treated at Cancer Treatment Centers of America between 04/01 and 11/04. QLI measures global QoL and QoL in four major subscales: health and physical, social and economic, psychological and spiritual, and family. All scores range from 0 to 30 with higher scores indicating better QoL. QLI subscales were dichotomized at the median to split the patient population into 2 distinct groups. Kaplan Meier method with Log Rank test was used to calculate survival. Results: Of 177 patients, 46 were newly diagnosed and 131 had prior treatment history. The median age was 53 years (range 25– 85 years). 8 patients had stage I disease, 16 stage II, 51 stage III, and 77 stage IV. Table 1 describes the median survival for all QLI subscales. Conclusions: Baseline levels of patient satisfaction with their health and physical functioning provided useful prognostic information in colorectal cancer. Interestingly, the other subscales that evaluate various existential and economic issues did not provide statistically significant differences in survival. These findings need to be evaluated further to ascertain which subscales of QLI have a role in predicting patients’ prognosis. [Table: see text] No significant financial relationships to disclose.


1986 ◽  
Author(s):  
John N. Morris ◽  
Samy Suissa ◽  
Sylvia Sherwood ◽  
Susan M. Wright ◽  
David Greer

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Tri Nurhudi Sasono

Abstract : Indicator of the health welfare through Sustanable Development Goals (SDGs) is to reduce the incidence of HIV-AIDS, decrease the rate of the epidemic and maintain the quality of life of people living with HIV-AIDS (PLWHA). Trend cases of HIV-AIDS is the most recent spread among people, especially housewives. In Malang until 2015 found 278 Housewife of 409 cases of AIDS. The prevalence of HIV-AIDS in Malang Regency is ranked second after Surabaya city in East Java. For the importance of public participation and citizen care AIDS Cahaya Care Turen take responsibility for the condition. Determination Rule Goverment number 2 2015 year on the Participation of the community response to HIV-AIDS in Malang as a legal rule. Concerned Citizens activities AIDS (WPA). WPA Cahaya Care Turen is increases HIV risk and quality of life PLWHA. The purpose of this study was to determine the role of Citizens AIDS Cahaya Care Quality of Care Turen against people living with HIV in Puskesmas Turen Malang. The study design using a quasi-experimental, with purposive sampling using a sampling technique. Total number of research subjects 23. Based on test results obtained with the Wilcoxon p value <0.005, which means that there is a significant difference before and after PLWHA joining participated in the WPA Cahaya Care Turen. The conclusion of this study is WPA activities involving people living with HIV and at risk groups can optimize compliance with antiretroviral drugs that have an impact on improving the quality of life of PLHIV. Suggestions in this research is done WPA Program activities are structured and ongoing cross-sector in order to improve the quality of life and empower PLWHA.Keywords : WPA Cahaya Care Turen, Quality of life, PLWHA Abstrak : Salah satu indikator kesejahteraan kesehatan melalui Sustanable Development Goals (SDGs) adalah menekan angka kejadian HIV-AIDS, menurunkan laju epidemik dan mempertahankan kualitas hidup Orang dengan HIV-AIDS (ODHA). Trend kasus HIV-AIDS terkini terbanyak adalah menjangkit dikalangan masyarakat khususnya pada ibu rumah tangga. Kabupaten Malang sampai dengan tahun 2015 ditemukan 278 Ibu Rumah Tangga dari 409 kasus AIDS. Prevalensi HIV-AIDS di Kabupaten Malang ini merupakan peringkat kedua di Jawa Timur setelah Kota Surabaya. Untuk itu pentingnya peran serta masyarakat dan warga peduli AIDS Cahaya Care Turen ikut bertanggung jawab terhadap kondisi tersebut. Penetapan Peraturan Bupati Malang no.2 th.2015 tentang Peran serta masyarakat penanggulangan HIV-AIDS di Kabupaten Malang diharapkan dapat mengurangi risiko penularan HIV dan meningkatkan kualitas hidup ODHA. Tujuan dari penelitian ini adalah untuk mengetahui Peran Warga Peduli AIDS Cahaya Care Turen terhadap Kualitas ODHA Di Wilayah Kerja Puskesmas Turen Kabupaten Malang. Desain penelitian menggunakan quasi eksperimen, dengan teknik sampling menggunakan purposive sampling. Jumlah subyek penelitian sejumlah 23. Berdasarkan hasil uji dengan Wilcoxon didapatkan nilai p value < 0.005 yang berarti bahwa terdapat perbedaan bermakna sebelum dan sesudah ODHA bergabung mengikuti kegiatan WPA Cahaya Care Turen. Kesimpulan dalam penelitian ini adalah kegiatan WPA dengan melibatkan ODHA dan kelompok beresiko dapat mengoptimalkan kepatuhan obat ART sehingga berdampak terhadap peningkatan kualitas hidup ODHA. Saran dalam penelitian ini adalah dilakukannya Program kegiatan WPA yang terstruktur dan berkesinambungan lintas sektor guna meningkatkan kualitas hidup dan memberdayakan ODHA.     Kata kunci : WPA Cahaya Care Turen, kualitas hidup, ODHA


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