scholarly journals Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery

2020 ◽  
Vol 14 (01) ◽  
pp. 74-79
Author(s):  
Chunli Dong ◽  
Haozheng Yuan ◽  
Renyan Xu ◽  
Hui Zhang ◽  
Lili He ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Infection Control ◽  
Bacterial Count ◽  
Incidence Rates ◽  
Pathogen Transmission ◽  
Control Group ◽  
Postoperative Infections ◽  
Post Surgery ◽  
Equivalent Area ◽  
Experimental Group

Introduction: The environment of the operating room (OR) is closely related to the postoperative complications of patients, and it is necessary to study, to what extent, the stringent management of the OR can reduce postoperative complications. Methodology: 426 patients who underwent surgery between January 2016 and December 2017 were selected from two class-100 laminar flow ORs of equivalent area, and were divided into an experimental group and a control group. Results: The experimental group had significantly lower total air-borne bacterial count in the OR than the control group 10 minutes before surgery (6.21 ± 4.14 vs. 11.58 ± 5.36 CFU/cm3), 10 minutes (15.67 ± 6.21 vs. 20.83 ± 5.78 CFU/cm3), 30 minutes (27.34 ± 8.18 vs. 39.56 ± 7.86 CFU/cm3) and 60 minutes (43.62 ± 7.66 vs. 51.63 ± 8.43 CFU/cm3) into surgery, and at the end of surgery (57.34 ± 7.67 vs. 69.33 ± 9.41 CFU/cm3) (all p < 0.05). The incidence rates of increased body temperature and leukocyte count 3 days post-surgery, and the duration of antibiotic therapy and hospital stay were significantly reduced in the experimental group compared to the control group (all p < 0.05). Furthermore, the total number of pathogens in the incision at 2 hours into surgery was also significantly lower in the experimental group than in the control group (p < 0.05). Conclusion: Stringent application of the infection control pathway is an efficacious measure for improving the air cleanliness of the neurosurgery OR, decreasing the incidence rates of postoperative complications and infection, as well as controlling pathogen transmission.

Analysis of Clinical Efficiency and Safety of Laparoscopic Anus-Conserving Operation for Ultralow Rectal Cancer

2019 ◽  
Vol 85 (5) ◽  
pp. 539-548
Author(s):  
Zhongkun Zuo ◽  
Ke Ding ◽  
Tenglong Tang ◽  
Leiyi Zhang ◽  
Weihui Peng ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Postoperative Complications ◽  
Hospital Stay ◽  
Incidence Rate ◽  
Anal Sphincter ◽  
Resection Margin ◽  
Survival Rates ◽  
Incidence Rates ◽  
Control Group ◽  
Experimental Group

To explore the efficiency and safety of laparoscopic anus-conserving operation for ultralow rectal cancer, we retrospectively reviewed 236 patients with ultralow rectal cancer who underwent laparoscopic anus-conserving operation (experimental group, n = 124) or conventional open surgery (control group, n = 112). Operation-related indexes, pathological results of mesentery, incidence rates of postoperative complications, anus preservation rates, anal sphincter controllability after surgery, and survival rates of the first, second, and third years after operation were compared between the two groups. The amount of intraoperative bleeding, first postoperative exhaust time, abdominal drainage, pain score, and hospital stay in the experimental group were significantly less than those in the control group ( P < 0.05). There were no significant differences in the postoperative circumferential resection margin, distal resection margin, number of dissected lymph nodes, successful resection rate, and quality of mesorectum between the two groups ( P > 0.05). The total incidence rate of postoperative complications, anal sphincter controllability, and survival rates after surgery were similar between the two groups ( P > 0.05). The anus preservation rate of the experimental group (84.7%) was significantly higher than that of the control group (69.6%) ( P < 0.05). Laparoscopic anus-conserving operation is effective and safe in treatment of patients with ultralow rectal cancer, which has advantages such as small trauma, less intra-operative bleeding, short hospital stay, rapid recovery, a low incidence rate of postoperative complications, and a high anus-preserving rate, so it is worthy of clinical application.

scholarly journals Effect of Low-Frequency Electric Pulse Technique Combined with Carboprost Methylate Suppositories on Recovery of Gastrointestinal Function and Postoperative Complications of Patients with Scarred Uterus Undergoing Secondary Cesarean Section

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Jinling Yan ◽  
Yongli Liu ◽  
Ruifen Jiao ◽  
Meixiang Li ◽  
Liqin Zhao
Keyword(s):  
Postoperative Complications ◽  
Electric Pulse ◽  
Low Frequency ◽  
Incidence Rates ◽  
Control Group ◽  
Gastrointestinal Function ◽  
Pulse Technique ◽  
Coagulation Function ◽  
Scarred Uterus ◽  
Experimental Group

The study aims to explore the effect of low-frequency electric pulse technique combined with carboprost methylate suppositories on recovery of gastrointestinal function and postoperative complications of patients with scarred uterus undergoing secondary cesarean section (C-section). The clinical data of 120 patients with scarred uterus undergoing secondary C-section treated in our hospital from February 2019 to February 2020 were retrospectively analyzed, and the patients were equally divided into experimental and control groups according to their admission order, where each group included 60 patients. After the operation, patients in the control group received routine nursing and conducted breastfeeding, and carboprost methylate suppositories were used for postoperative hemostasis. Those in the experimental group received low-frequency electric pulse technique for comprehensive treatment to compare their coagulation function indicators, recovery of gastrointestinal function, incidence rates of postoperative complications, and involution of uterus. No significant between-group differences in patients’ general information such as gestational weeks, gravidity, and number of times receiving C-section were observed ( P > 0.05 ). Compared with the control group after the operation, patients in the experimental group obtained significantly better coagulation function indicators ( P < 0.001 ) and presented better gastrointestinal function recovery ( P < 0.001 ), significantly lower incidence rates of postpartum hemorrhage, retention of urine, deep venous thrombosis of lower limb, rupture of uterus, and endometrial cavity fluid ( P < 0.05 ), and significantly better involution of uterus ( P < 0.001 ). In conclusion, combining low-frequency electric pulse technique with carboprost methylate suppositories can lower the incidence rates of postoperative complications for patients with scarred uterus undergoing secondary C-section, improve their coagulation function, promote the recovery of gastrointestinal function, and present the desirable involution of uterus, which should be promoted in practice.

scholarly journals Effect of Feed Supplemented With Vitamin C on Microbial Flora of Swine Faeces and Blood Morphology

2012 ◽  
Vol 56 (2) ◽  
pp. 171-175
Author(s):  
Beata Trawińska ◽  
Jerzy Lechowski ◽  
Antoni Polonis ◽  
Marta Kowaleczko
Keyword(s):  
Vitamin C ◽  
Pathogenic Bacteria ◽  
Bacterial Species ◽  
Intestinal Flora ◽  
Bacterial Count ◽  
Control Group ◽  
Total Bacterial Count ◽  
E Coli ◽  
Bacteriological Evaluation ◽  
Experimental Group

Abstract The studies involved gilts 6 weeks pre-partum allocated into the control and experimental groups. The experimental group received vitamin C at the dose of 2.5g/100 kg b.w./day. Faeces for analyses were collected for 3- and 6- week period of vitamin C dietary inclusion. The faecal material underwent quantitative and qualitative bacteriological evaluation. The count of Enterobacteriaceae was evaluated. The qualitative examination of these bacteria was made using the micro-plate method API 20E. Feed supplemented with vitamin C contributed to a statistically significant decline of the total bacterial count of Enterobacteriaceae in faeces. The qualitative bacterial analyses showed the presence of E. coli, Providecia sp., Proteus sp., and Salmonella sp. in the control and experimental groups. Enterobacter sp. was recovered only in the control group, while Lactobacillus sp. in the experimental group. The dietary administration of vitamin C significantly decreased the number of the studied bacterial species, except Salmonella rods. No statistically significant differences in the number of most blood morphotic elements following the 6- week supply of vitamin C were found; only the granulocyte count significantly increased, while lymphocyte numbers declined. Ascorbic acid inhibited the growth of pathogenic intestinal flora and reduced the pathogenic and relatively pathogenic bacteria count in the gastrointestinal tract and notably contributed to enhanced growth of beneficial bacteria.

scholarly journals The torsional alignment changed significantly in growing rabbits after patella dislocation by a three-dimensional measurement

2020 ◽  
Author(s):  
Jinghui Niu ◽  
Qi Qi ◽  
Kang Piao ◽  
Kuo Hao ◽  
Fei Wang
Keyword(s):  
Three Dimensional ◽  
Patella Dislocation ◽  
Control Group ◽  
Lateral Dislocation ◽  
Post Surgery ◽  
Femoral Version ◽  
Three Dimensional Measurement ◽  
Torsional Malalignment ◽  
And Control ◽  
Experimental Group

Abstract Background: Torsional malalignment has been considered as a risk factor for patella dislocation. But the influence of patella dislocation for torsional alignment development remains unknown. The present study aims to investigate whether the torsion alteration of the hindlimb occur after patella dislocation in growing rabbits. Methods: In the present study, 30 one-month old rabbits were included. The experimental group consists of 30 left knees of rabbits and were underwent patella lateral dislocation. And the control group consists of 30 right knees and no surgical procedure was performed. A CT scan was performed on each knee when the surgery was finished and at the time the rabbits were skeletal mature (5 months post-surgery). The angles of femoral version and tibial torsion were measured using a three-dimensional method and analyzed between the experimental group and control group. Results: The femoral version and tibia torsion in the experimental and control group immediately after surgery were not different significantly. However, 5 months after surgery, the femoral version angle of the experimental group (-5.50±6.13°) was significantly different with that of the experimental group (-10.90±4.74°)(P < 0.05). But the tibia torsion angle in the experimental group (7.17±7.25°) and control group (4.47±6.34°) were not significantly different (P = 0.144). Conclusion: From this study, patella dislocation can lead to alteration of femoral version in growing rabbits. This may indicate the early treatment for patella dislocation in children is particularly important to avoid torsional malalignment in the future. These findings may develop pathology and etiology of patella dislocation.

scholarly journals Analysis of the Effect of Cluster Nursing in Postoperative Hypertensive Cerebral Hemorrhage

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Pingxia Zheng ◽  
Jia Wang ◽  
Yan Ma ◽  
Jingjing Xu ◽  
Qianping Zhu
Keyword(s):  
Postoperative Complications ◽  
Intracerebral Hemorrhage ◽  
Treatment Compliance ◽  
Nursing Intervention ◽  
Control Group ◽  
Total Incidence ◽  
Hypertensive Intracerebral Hemorrhage ◽  
And Control ◽  
Experimental Group

Hypertensive intracerebral hemorrhage is a common condition in clinic. Due to the improvement of minimally invasive technology, its therapeutic effect is good, but there are still postoperative complications. The corresponding routine nursing intervention is not effective in the rehabilitation of postoperative patients with hypertensive intracerebral hemorrhage. In this paper, cluster nursing was applied to the treatment of postoperative patients with hypertensive intracerebral hemorrhage. For this purpose, a retrospective study or experiment was conducted on 150 patients with hypertensive intracerebral hemorrhage in the hospital specifically from January 2019 to December 2020. According to the nursing strategy, patients were divided into experimental (n = 75) and control groups (n = 75), respectively. The control group adopted routine nursing mode, whereas the experimental group adopted cluster nursing mode. The treatment compliance of patients in the experimental group was 86.67%, while that in the control group was 73.33% ( P  < 0.05). The total incidence of postoperative complications in the experimental group was 3.2%, which was lower than 25% in the control group ( P  < 0.05). The motor function score of the experimental group was better than that of the control group ( P  < 0.05). The application of cluster nursing in postoperative patients with hypertensive intracerebral hemorrhage is feasible, and its nursing effect is significant, which can not only reduce the incidence of postoperative complications but also improve patients’ compliance and quality of life. It has good application value.

scholarly journals Phase II trial of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer after curative surgery

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Biao Fan ◽  
Zhaode Bu ◽  
Ji Zhang ◽  
Xianglong Zong ◽  
Xin Ji ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Postoperative Complications ◽  
Advanced Gastric Cancer ◽  
Phase Ii Trial ◽  
Locally Advanced ◽  
Control Group ◽  
Radical Gastrectomy ◽  
Curative Surgery ◽  
Locally Advanced Gastric Cancer ◽  
Experimental Group

Abstract Background HIPEC is an emerging procedure to treat peritoneal metastasis of gastric cancer. Data about HIPEC in locally advanced gastric cancer is scarce. The purpose of this trial is to evaluate the safety and toxicity of prophylactic HIPEC with cisplatin for patients with locally advanced gastric cancer. Methods From March 2015 to November 2016, a prospective, randomized phase II trial was conducted. After radical gastrectomy, patients in the experimental group underwent HIPEC with cisplatin followed by adjuvant chemotherapy with SOX regime. Patients in the other group were treated with SOX regime alone. Postoperative complications and patient survival were compared. Results In total, 50 patients were eligible for analyses. No significant difference was found in the incidence of postoperative complications including anastomotic/intestinal leakage, liver dysfunction, bone marrow suppression, wound infection and ileus (P > 0.05). Mean duration of hospitalization after radical gastrectomy was 11.7 days. 12.2 days in experimental group and 10.8 days in control group respectively (P = 0.255). The percentage of patients with elevated tumor markers was 12.1% in experimental group, which was significantly lower than 41.2% in control group (P = 0.02). 3-year RFS of patients who treated with or without prophylactic HIPEC were 84.8 and 88.2% respectively (P = 0.986). In the multivariate analysis, pathological T stage was the only independent risk factor for the RFS of patients (P = 0.012, HR =15.071). Conclusion Additional intraoperative HIPEC with cisplatin did not increase postoperative complications for locally advanced gastric cancer after curative surgery. Prophylactic HIPEC with cisplatin was safe and tolerable, while it did not reduce the risk of peritoneal recurrence in this trial, supporting further studies to validate the efficacy of it. Trial registration Chinese Clinical Trial Registry, ChiCTR2000038331. Registered 18 September 2020 - Retrospectively registered, http://www.chictr.org.cn/showproj.aspx?proj=59692.

A Quasi – Experimental Study to Assess the Effectiveness of Structured Teaching Programme Regarding Knowledge of Personal Protective Equipment (Ppe) use in Among Nursing Students at Selected Nursing Institute Faridabad (Haryana)

2021 ◽  
pp. 469-472
Author(s):  
Sudhir Singh
Keyword(s):  
Nursing Students ◽  
Infection Control ◽  
Health Workers ◽  
Control Group ◽  
Teaching Programme ◽  
Structured Teaching ◽  
Post Test ◽  
Quasi Experimental ◽  
And Control ◽  
Experimental Group

Health worker are constantly exposed to infectious pathogens while they provide care to the patients. There are plenty of infection, for health workers to get affected by infection, so infection control measures are most necessary for health workers. By practicing infection control techniques, the health workers can avoid spreading microorganism. This can be possible when there is up gradation of knowledge and attitude of health workers regarding PPE. In this study the researcher Aimed: to assess the effectiveness of Structured teaching programmed on use of PPE among nursing students. Research design: adopted for this study was quasi experimental design, samples for this study was selected through convenient sampling technique. Total sample size for study was 100. Pre- test was done for the subjects in both group experimental and control group and experimental group received structured teaching programme regarding PPE use. Control group subjects did not receive any special intervention. On the seventh day took post- test among subjects in both groups to assess the structured teaching programme regarding use of PPE. Data collection were analyzed with the help of descriptive and inferential statistics. Results: Mean post test score in experimental and control group was 25.72and 13.71 respectively. The mean difference score was 12.01. The standard deviation score in experimental group was 2.170 and in control group 9.131. The ‘t’ Value was 59.524 which was statistically significant at ‘P’ value 0.000. Conclusion: This study imposes importance of suitable health teaching intervention through proper structure to the nursing students, for use of PPE.

Use of bacterial cellulose film for repair of bile duct injury in pigs

2020 ◽  
Vol 35 (3) ◽  
pp. 331-341
Author(s):  
Gilberto FS de Abreu ◽  
Laécio L Batista ◽  
Danielle CN Adeodato ◽  
Amanda V de Albuquerque ◽  
Rafaela S Ferraz-Carvalho ◽  
...  
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Bacterial Cellulose ◽  
Bile Duct Injury ◽  
Healing Process ◽  
Intraoperative Ultrasound ◽  
Control Group ◽  
Cellulose Film ◽  
Post Surgery ◽  
Experimental Group

Background/objective The aim was to evaluate the use of bacterial cellulose film and bile duct autograft in repairing critical common bile duct injury in pigs. Methods A prospective experimental analytical study was carried out on 20 Sus Domesticus, Piau suidae swine, divided into a control group ( n = 10) and an experimental group ( n = 10) divided into two subgroups: bacterial cellulose film E1 and bacterial cellulose film E2 to which bacterial cellulose film was randomly allocated. The control group underwent two complete critical common bile duct sections 10 mm apart, while the experimental group with a single critical common bile duct defect underwent a 10 mm section of the longitudinal shaft with edge resection. The defects in the control group were treated with end-to-end conventional anastomosis using polyglycolic 6–0 surgical thread and the experimental group with bacterial cellulose film by continuous suture using the same material. The animals were clinically evaluated throughout the experiment on days D150 (bacterial cellulose film E1), D225 (control group), and D330 (bacterial cellulose film E2) and by intraoperative ultrasound examination related to histopathological and biochemical findings. Results The intraoperative ultrasonography detected the changes resulting from the common bile duct anastomosis in the control group that produced a considerable incidence of ductal narrowing and obstruction to the biliary flow. In the bacterial cellulose film E2 group, there was an increase in inflammation intensity, granulomatous reaction, fibrosis, and vessels density, without producing bile duct dilation in the ultrasonography assessment. Biochemical analysis of liver enzymes yielded results in the normal range confirming preservation of liver function at the different post-surgery time points. Conclusion Bacterial cellulose film, when used as a graft for bile duct repair, proved to be a biocompatible material that produced a complete healing process and biliary flow continuity.

scholarly journals The Effect of Tranexamic Acid Administration on Early Endothelial Damage Following Posterior Lumbar Fusion Surgery

2021 ◽  
Vol 10 (7) ◽  
pp. 1415
Author(s):  
Hye Jin Kim ◽  
Bora Lee ◽  
Byung Ho Lee ◽  
So Yeon Kim ◽  
Byongnam Jun ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Tranexamic Acid ◽  
Lumbar Fusion ◽  
Endothelial Glycocalyx ◽  
Control Group ◽  
Fusion Surgery ◽  
Posterior Lumbar Fusion ◽  
Lumbar Fusion Surgery ◽  
Post Surgery

Tranexamic acid (TXA) protects against endothelial glycocalyx injury in vitro. We aimed to evaluate whether TXA could protect against endothelial glycocalyx degradation in patients undergoing posterior lumbar fusion surgery. Patients aged 30–80 years were enrolled. The TXA group was administered a loading dose of 10 mg/kg, followed by a 1 mg/kg/h infusion. Serum syndecan-1 and heparan sulfate concentrations, which are biomarkers of glycocalyx degradation, were measured at preoperative baseline (T0), immediately post-surgery (T1), and 2 h post-surgery (T2). Postoperative complications were assessed, including hypotension, desaturation, and acute kidney injury. Among the 121 patients who completed the study, 60 received TXA. There were no significant differences in the marker concentrations at each time point. However, the postoperative increase in syndecan-1 levels from baseline was significantly attenuated in the TXA group compared with the control group (median (interquartile range); T1 vs. T0: −1.6 (−5.3–2.6) vs. 2.2 (−0.7–4.8), p = 0.001; T2 vs. T0: 0.0 (−3.3–5.5) vs. 3.6 (−0.1–9.3), p = 0.013). Postoperative complications were significantly associated with the magnitude of the change in syndecan-1 levels (for T2 vs. T0: odds ratio: 1.08, 95% confidence interval: 1.02–1.14, p = 0.006). TXA administration was associated with reduced syndecan-1 shedding in patients undergoing posterior lumbar fusion surgery.

scholarly journals Effects of Education on the Use of Personal Protective Equipment for Reduction of Contamination: A Randomized Trial

2020 ◽  
Vol 6 ◽  
pp. 237796082094062
Author(s):  
Jeong Hwa Yeon ◽  
Yong Soon Shin
Keyword(s):  
Infection Control ◽  
Education Program ◽  
Personal Protective Equipment ◽  
Contaminated Sites ◽  
Contaminated Site ◽  
Control Group ◽  
Protective Equipment ◽  
Increased Risk ◽  
And Control ◽  
Experimental Group

Introduction Accurate doffing personal protective equipment (PPE) is one of the key practices of infection control because of increased risk of infection transmission caused by medical garments or environmental contamination. Objectives The study aimed to develop a reality-based education program and identify its effects on nurses’ knowledge, attitudes, and contamination after PPE doffing. Methods Randomized control group pretest–posttest design. A total of 56 nurses were randomly assigned to experimental ( n = 28) and control ( n = 28) groups. The experimental group underwent a new reality-based education program to improve PPE use. Subsequently, participants were assessed on knowledge of and attitude toward PPE use, as well as number and area of contaminated sites after removing PPE and mask fitting test. Results There were no significant differences in knowledge and attitude to PPE use. The experimental group had significantly fewer contaminated sites than the control group (42 vs. 89), and a significantly lower mean contaminated site area (16.63 ± 24.27 vs. 95.41 ± 117.51 cm2). The tuberculosis mask fitting test success rates were 68% and 50% in the experimental and control groups, respectively, but the difference was not significant. Conclusion The reality-based education on use of PPE helps to reduce contamination and improve performance related to the use of PPE for infection control.

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