scholarly journals The presence of periopathogenic bacteria in subgingival and atherosclerotic plaques – An age related comparative analysis

2018 ◽  
Vol 12 (12) ◽  
pp. 1088-1095 ◽  
Author(s):  
Ibrahim Kannosh ◽  
Danijela Staletovic ◽  
Bosko Toljic ◽  
Milena Radunovic ◽  
Ana Pucar ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Age Groups ◽  
Atherosclerotic Plaques ◽  
Subgingival Plaque ◽  
Periodontal Pathogens ◽  
Periodontal Bacteria ◽  
Oral Microflora ◽  
Age Related ◽  
Significant Difference ◽  
Tannerella Forsythensis

Introduction: There is a known connection between periodontitis and atherosclerosis and the presence of periopathogens in blood vessels. However, changes of the oral microflora related to the aging process and its possible effects on atherosclerosis, have yet to be analyzed. The aim of this study was to assess temporal changes in the frequency of periodontal bacteria in the subgingival plaque and in atherosclerotic blood vessels of patients with atherosclerosis. Methodology:The study included 100 patients with atherosclerosis and periodontitis, divided into two groups, below and over 60 years of age. Clinical examinations were performedand subgingival plaque specimens were collected as well as biopsy specimens from the following arteries: coronary (34), carotid (29), abdominal (10), femoral (10), mammary (13) and iliac (4). Subgingival and artery specimens were subjected to PCR detection of 5 major periodontal pathogens: Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi), Aggregatibacter actinomycetemcomitans (Aa), Tannerella forsythensis (Tf) and Treponema denticola (Td). Results:Tf was the most and Td the least frequent bacteria in both age groups and in both types of samples. The frequencies of bacteria in subgingival versus atherosclerotic samples were: Tf (76%:53%), Pi (71%:31%), Pg (60%:38%), Aa (39%:14%) and Td (21%:6%). Only Aa and Pi showed a significant difference of prevalence between younger and older patients. The most colonized artery was a. coronaria, followed by a. carotis, a. abdominalis, a. mammaria, and a. femoralis. Conclusions: Patient’s age and the distance of a given blood vessel from the oral cavity influenced microbiological findings in the atherotic plaque.

The influence of osteopathic correction on the rate of various rhythms of the body

2019 ◽  
pp. 64-71 ◽  
Author(s):  
A. E. Chernikova ◽  
Yu. P. Potekhina
Keyword(s):  
Heart Rate ◽  
Respiratory Rate ◽  
Age Groups ◽  
Biomechanical Properties ◽  
Dispersion Analysis ◽  
The Body ◽  
Body Tissues ◽  
Age Related ◽  
Significant Difference ◽  
Before And After

Introduction. An osteopathic examination determines the rate, the amplitude and the strength of the main rhythms (cardiac, respiratory and cranial). However, there are relatively few studies in the available literature dedicated to the influence of osteopathic correction (OC) on the characteristics of these rhythms.Goal of research — to study the influence of OC on the rate characteristics of various rhythms of the human body.Materials and methods. 88 adult osteopathic patients aged from 18 to 81 years were examined, among them 30 men and 58 women. All patients received general osteopathic examination. The rate of the cranial rhythm (RCR), respiratory rate (RR) heart rate (HR), the mobility of the nervous processes (MNP) and the connective tissue mobility (CTM) were assessed before and after the OC session.Results. Since age varied greatly in the examined group, a correlation analysis of age-related changes of the assessed rhythms was carried out. Only the CTM correlated with age (r=–0,28; p<0,05) in a statistically significant way. The rank dispersion analysis of Kruskal–Wallis also showed statistically significant difference in this indicator in different age groups (p=0,043). With the increase of years, the CTM decreases gradually. After the OC, the CTM, increased in a statistically significant way (p<0,0001). The RCR varied from 5 to 12 cycles/min in the examined group, which corresponded to the norm. After the OC, the RCR has increased in a statistically significant way (p<0,0001), the MNP has also increased (p<0,0001). The initial heart rate in the subjects varied from 56 to 94 beats/min, and in 15 % it exceeded the norm. After the OC the heart rate corresponded to the norm in all patients. The heart rate and the respiratory rate significantly decreased after the OC (р<0,0001).Conclusion. The described biorhythm changes after the OC session may be indicative of the improvement of the nervous regulation, of the normalization of the autonomic balance, of the improvement of the biomechanical properties of body tissues and of the increase of their mobility. The assessed parameters can be measured quickly without any additional equipment and can be used in order to study the results of the OC.

scholarly journals Age Related Variation in Feminine Handwriting among Population Groups of Delhi, India

2018 ◽  
Vol 6 (1) ◽  
pp. 1-6
Author(s):  
Vijit Deepani ◽  
A.K Kapoor ◽  
Monika Saini
Keyword(s):  
Significant Variation ◽  
Research Result ◽  
Age Groups ◽  
Population Group ◽  
Population Groups ◽  
Related Variation ◽  
Age Related ◽  
Significant Difference ◽  
Micro Features ◽  
Lower Loop

Background: Handwriting is a uniquely human trait which progresses and evolves during lifetime and declines with age. The aim of the present paper is to assess variation in handwriting features with age among female writers of select population groups of Delhi, India (for roman script). Method: A total of 405 handwritten samples were obtained from female (n=405) writers in the age range of 14-60 years. Writers were stratified into three age groups (≤ 18 years, 19-38 years and ≥39 years) in accordance to population group. Macro- and micro-features of handwriting were extracted from the scanned handwritten samples. These features were subjected to statistical analysis in the objective driven research. Result: The mean difference among age groups for pen pressure, height of handwriting and handwriting connectivity was statistically significant (p < 0.001). Significant difference was also observed among age groups for all micro-features of handwriting selected in the present study, namely, nature of ‘i’ – dot (p < 0.001), nature of lower loop of ‘g’ (p < 0.01); nature of‘d’- stem (p < 0.01), nature of ‘m’-hump (p < 0.05) and ‘r’- shape (p < 0.001). Conclusion: The present study showed that there was a significant variation in both macro- and micro- features of handwriting with respect to age of the writer. Pen pressure, height of handwriting and handwriting connectivity were prominent macro-features that addressed age related variation in handwriting. In addition, significant variation was observed among age groups for all micro-features of handwriting selected in the present study. The present study has immense forensic significance as it can assist to analyze age of the writer on the basis of handwriting characteristics.

scholarly journals MONITORING HEALTH INDICES IN FEMALES OF DIFFERENT AGE GROUPS

2019 ◽  
Vol 98 (8) ◽  
pp. 827-832
Author(s):  
Olga S. Aminova ◽  
N. N. Tyatenkova ◽  
Yu. E. Uvarova ◽  
S. V. Yakovlev
Keyword(s):  
Age Groups ◽  
Blood Cholesterol ◽  
Dynamic State ◽  
Social Functions ◽  
Total Blood ◽  
Health Indices ◽  
Age Related ◽  
Significant Difference ◽  
Definition Of ◽  
Functional Examination

Introduction. Health - is a complex and at the same integral multivariable dynamic state, developing in the process of realization of the genetic potential in a particular social and ecological environment, which permits a person to carry out its biological and social functions. Material and methods Health indices deteriorate with age. In this situation, special attention should be paid to older age groups. However, recent studies prefer to investigate young people. Data about health status of different age groups is not well investigated. Survey of 415 women aged 20 to 59 years residing on Yaroslavl region has been performed. Evaluation of age-related changes in health indices included questionnaire, morphological and functional examination, definition of physical development and adaptative potential according to the calculated indices and reference values. Results. The study examined the dynamics of health indices and established a statistically significant difference in the gain in body weight, blood pressure, total blood cholesterol, decreased lung capacity relative to body mass and adaptive capacity of the cardiovascular system with the age. Analysis of the incidence showed that chronic diseases incidence has increased from 56% in the 20-29 years group to 88% among 50-59 years old persons. Diseases of cardiovascular and musculoskeletal system (48-49%) become predominant pathology with age. Evaluation of lifestyle shows that poor physical activity and sleep disorders were registered in 77% and 32% respectively regardless of age. Eating disorders were registered in 41% patients aged of 20-29 years. Ratio tobacco users decreased from 23% to 10% with age, while the number of cigarettes smoked per day was increased. Сonclusion. The study established the negative dynamics of health indices to be typical for women aged 20-59 years, while the rate of deterioration exceeds the average one in the Russian population. Self-preservation behavior is not predominant in all age groups, it is typical only for 3% of young women and 11-15% of other groups.

scholarly journals Does age affect symptom recovery after sports-related concussion? A study of high school and college athletes

2013 ◽  
Vol 12 (6) ◽  
pp. 537-544 ◽  
Author(s):  
Young M. Lee ◽  
Mitchell J. Odom ◽  
Scott L. Zuckerman ◽  
Gary S. Solomon ◽  
Allen K. Sills
Keyword(s):  
High School ◽  
College Athletes ◽  
Age Groups ◽  
Reliable Change Index ◽  
Health Concern ◽  
P Value ◽  
Symptom Scale ◽  
Older Athletes ◽  
Age Related ◽  
Significant Difference

Object Sport-related concussions (SRCs) in high school and college athletes represent a significant public health concern. Research suggests that younger athletes fare worse symptomatically than older athletes after an SRC. Using reliable change index (RCI) methodology, the authors conducted a study to determine if there are age-related differences in number, severity, and resolution of postconcussion symptoms. Methods Between 2009 and 2011, baseline measures of neurocognitive functions and symptoms in high school and college athletes were entered into a regional database. Seven hundred forty of these athletes later sustained an SRC. Ninety-two athletes in the 13- to 16-year-old group and 92 athletes in the 18- to 22-year-old group were matched for number of prior concussions, sex, biopsychosocial variables, and days to first postconcussion testing and symptom assessment. A nonparametric Mann-Whitney U-test was used to compare the severity of each of 22 symptoms comprising the Total Symptom Scale (TSS) at baseline and first postconcussion test. To obtain a family-wise p value of 0.05 for each test, the significance level for each symptom comparison was set at an alpha of 0.05/22 = 0.0023. The number of days to return to baseline TSS score was compared using the RCI methodology, set at the 80% confidence interval, equal to a change in raw score of 9.18 points on the TSS. Results There was no statistically significant difference in symptom presence, symptom severity, and total symptoms between the age groups at baseline or at postconcussion testing. There was no statistically significant difference in return to baseline symptom scores between the age groups. Conclusions Using RCI methodology, there was no statistically significant difference between younger and older athletes in return to baseline symptoms postconcussion.

scholarly journals Age-Related Success with Elective Single versus Double Blastocyst Transfer

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Brooke E. Friedman ◽  
Lynn B. Davis ◽  
Ruth B. Lathi ◽  
Lynn M. Westphal ◽  
Valerie L. Baker ◽  
...  
Keyword(s):  
Age Groups ◽  
Blastocyst Transfer ◽  
Multiple Gestation ◽  
Optimal Outcome ◽  
Singleton Pregnancy ◽  
Multiple Gestations ◽  
Age Related ◽  
Single Blastocyst Transfer ◽  
Significant Difference ◽  
Single Versus

Background. Although the optimal outcome of assisted reproductive technology (ART) is a healthy singleton pregnancy, the rate of twin gestation from ART in women over the age of 35 is persistently high. Methods/Findings. We compared clinical pregnancy rates (PRs), ongoing pregnancy/live birth rates, and multiple gestation rates (MGRs) in 108 women who chose elective single blastocyst transfer (eSBT) to 415 women who chose elective double blastocyst transfer (eDBT) at a hospital-based IVF center. There was no significant difference in PR between eSBT and eDBT (57.4% versus 50.2%, ) nor between eSBT and eDBT within each age group: <35, 35–37, 38–40, and >40. The risk of multiple gestations, however, was greatly increased between eSBT and eDBT (1.6 versus 32.4%, ), and this difference did not vary across age groups. Conclusion(s). Women undergoing eDBT are at uniformly high risk of multiple gestation regardless of age. eSBT appears to significantly lower the risk of multiple gestation without compromising PR.

scholarly journals DETECTION AND QUANTITATION OF RED COMPLEX BACTERIA IN SUBGINGIVAL PLAQUE BY USING FLUORESCENT IN SITU HYBRIDIZATION (FISH)

2017 ◽  
Vol 5 (11) ◽  
pp. 279-289
Author(s):  
Kishore G. Bhat ◽  
Aradhana Chhatre ◽  
Vijay M. Kumbar ◽  
Manohar S. Kugaji ◽  
Sanjeevani Patil
Keyword(s):  
In Situ Hybridization ◽  
Diagnostic Tool ◽  
Fluorescent In Situ Hybridization ◽  
High Sensitivity ◽  
Clinical Samples ◽  
Subgingival Plaque ◽  
Periodontal Pathogens ◽  
Significant Difference ◽  
Strong Linear Relationship

Motivation/Background: Red complex bacteria are proven periodontal pathogens. In dentistry, there is a need to identify and quantitate the organisms from the diseased sites quickly and reliably. Since culture requires several days, molecular methods are being used frequently to detect these bacteria.  Among them, Fluorescent in situ hybridization (FISH) is rapid, sensitive and quantitative. An attempt is made here to evaluate the applicability of this technique as a diagnostic tool in periodontology. Method: Subgingival plaque was collected from participants, fixed with paraformaldehyde and subjected to FISH. Fluorescently labeled oligonucleotide probes were used for hybridization. After the procedure, the fluorescently stained bacteria were identified and counted from the smear and quantitated using a simple grading. Results: There was a significant difference in the prevalence and numbers of red complex bacteria in healthy and diseased subjects. A strong linear relationship existed between P. gingivalis, T. forsythia and T. denticola. Conclusions: The procedure used in the study is simple, rapid and can be easily adaptable. It also has a high sensitivity and has the ability to detect a single bacterial cell. The method can be directly applied to the clinical samples and can be used as a rapid diagnostic tool in periodontics.

scholarly journals A postmortem study on the volume of the human kidney

2015 ◽  
Vol 23 (1) ◽  
pp. 73-77
Author(s):  
Fatema Johora ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Dilruba Siddiqua ◽  
Hasna Hena ◽  
Shamim Ara
Keyword(s):  
Left Kidney ◽  
Age Groups ◽  
Human Kidney ◽  
Kidney Volume ◽  
Kidney Size ◽  
Cross Sectional ◽  
Medical College ◽  
Age Related ◽  
Significant Difference ◽  
The Right

Context: Kidney volume is a sensitive index of kidney size for the detection of renal abnormalities. It is also excellent predictor of renal function and correlates very well with body indexes. The present study was done on cadaveric specimens to see the age related changes in the volume of the kidney in a Bangladeshi population and to compare with the previous local and foreign studies. Methods: This cross-sectional, descriptive study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from July 2008 to June 2009, based on collection of 140 post mortem human kidneys from 70 unclaimed dead bodies which were in the morgue under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. All the samples were divided into three age groups including A (10-19 years), B (20-39 years) and C (40-59 years). The length, breadth and thickness of each kidney were measured by using a slide calipers and recorded. Then the volume was determined by using prolate ellipsoid formula i.e. length × breadth × thickness × 0.52. Results: The volume of the right and left kidneys were found 54.46±4.02 cm3 and 53.15±1.98 cm3 in group A, 78.31±10.41 cm3 and 75.90±8.32 cm3 in group B, 74.47±6.22 cm3 and 73.34±6.80 cm3 in group C. No statistically significant difference was found between the right and the left kidney in any group. However, statistically significant differences were evident between A & B and A & C (P<0.001). Conclusion: No difference was found in volume between the right and the left kidney in any group. However, kidney volume was found to increase with advancing age in apparently healthy Bangladeshi people. DOI: http://dx.doi.org/10.3329/jdmc.v23i1.22698 J Dhaka Medical College, Vol. 23, No.1, April, 2014, Page 73-77

scholarly journals COMPARATIVE CHARACTERISTICS OF THE PARAMETERS OF THE CEREBELLUM OF MEN AT A YOUNG AND OLD AGE ACCORDING TO MAGNETIC RESONANCE TOMOGRAPHY

2021 ◽  
Vol 28 (4) ◽  
pp. 68-72
Author(s):  
Anatoly A. Balandin ◽  
Lev M. Zheleznov ◽  
Irina A. Balandina ◽  
Valery S. Shelud'ko
Keyword(s):  
Magnetic Resonance ◽  
Old Age ◽  
Age Groups ◽  
Magnetic Resonance Tomography ◽  
Cerebellar Hemisphere ◽  
Morphometric Study ◽  
Age Related ◽  
Group I ◽  
Significant Difference ◽  
The Right

Investigation which devoted to the study of the age characteristics of the human body are becoming increasingly important. Magnetic resonance tomography is the most informative diagnostic method for intravital visualization of tissues and structures of the brain. It also allows you to more accurately see the picture of morphological features with age-associated changes. The aim of the study was to carry out a comparative analysis of the age-related morphometric characteristics of the cerebellum in male with mesocranic type of cranium in young and old age according to the data of magnetic resonance tomography. The analysis of the results of a morphometric study of the cerebellum on tomograms of 91 men examined for medical reasons was carried out. Depending on the age, the subjects were divided into two groups. Group I included 52 young men (22–27 years old, inclusive), group II included 39 elderly men (from 78 to 83 years old, inclusive). The transverse, longitudinal and vertical dimensions of the cerebellum were determined. When comparing the parameters of the linear dimensions of the cerebellum in the studied age groups of men, a statistically significant decrease in all indicators in old age compared with young age was revealed (p=0.042). There was no statistically significant difference between the parameters of the longitudinal and vertical sizes of the cerebellar hemispheres in individuals of each age group (p>0.05); there is a tendency for these sizes to prevail in the right cerebellar hemisphere. The results obtained can serve as the equivalent of the age-related anatomical norm of the cerebellum in young and old men, which will make it possible to use these data in basic and clinical research, as well as in medical practice.

Chromosomal alterations and DNA content in rats during ageing

Genome ◽  
1989 ◽  
Vol 32 (3) ◽  
pp. 389-392 ◽  
Author(s):  
Sarmistha Sen ◽  
Geeta Talukder ◽  
Archana Sharma
Keyword(s):  
Bone Marrow ◽  
Dna Content ◽  
Bone Marrow Cells ◽  
Age Groups ◽  
Chromosome Analysis ◽  
Male Rats ◽  
Age Related ◽  
Significant Difference ◽  
Feulgen Cytophotometry

Chromosome analysis of bone marrow cells from 96 sex-matched Rattus norvegicus of 12 different age groups showed a significant increase in hypodiploid cells with ageing. However, in meiotic preparations from gonadal cells of male rats the frequency of hypodiploid or hyperdiploid cells did not change significantly. In situ DNA estimation of bone marrow nuclei, following Feulgen cytophotometry, also did not show any significant difference with gradual age changes.Key words: senescence, DNA content, age-related changes.

Is Age Related Fibrinogen Affected by Warfarin?.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 4117-4117
Author(s):  
Roger C. Munro ◽  
Lisa J. Wakeman ◽  
Saad Al-Ismail
Keyword(s):  
Statistical Significance ◽  
Plasma Concentrations ◽  
Age Groups ◽  
Warfarin Group ◽  
Published Evidence ◽  
Age Related ◽  
Age Gap ◽  
Significant Difference ◽  
Warfarin Treatment ◽  
The Difference

Abstract Introduction: There is published evidence which indicates that advancing age may be associated with higher plasma concentrations of fibrinogen. There is also evidence that derived fibrinogen values are significantly higher than Clauss measurements and that this discrepancy is greater in patients receiving warfarin. The purpose of this study was to determine whether age related derived fibrinogen levels are similar in both warfarin and non-warfarin groups. Methods: Venous samples were collected into siliconised glass B-D Vacutainers containing tri-sodium citrate (Ref: 367691) from 1000 patients receiving long term warfarin treatment and an equal number of age-matched patients not receiving warfarin. Genders were equally represented in both groups. Patients in both groups were categorized into 5 years age bands as follows: &lt;40 n=23: 40–44 n=20: 45–49 n=43; 50–54 n=74: 55–59 n=113: 60–64 n=155: 65–69 n=178: 70–74 n=191: 75–79 n=124; 80–84 n=56: 85–89 n=23. Derived fibrinogen was measured in each patient on an ACL300R coagulometer (I L) within 1 hour of collection using IL PT-FIB HS Plus reagent and following the manufacturer’s protocol. Appropriate CLSI guidelines were followed throughout. A normal probability plot of the data was performed to confirm that it did not deviate too much from the normal distribution. Results: The T-test for independent samples using the separate variance estimate showed that there was a statistically significant difference in the mean fibrinogen between patients on warfarin and those not on warfarin (p&lt;0.05) in each group except for the last (85–89 years). There was a statistically significant difference (ANOVA) in the fibrinogen levels of patients of different age in both warfarinised and non-warfarinised groups (p&lt;0.05). The modified least significance procedure in the ANOVA test showed that in the non-warfarin group, most of significant difference in fibrinogen between the different age groups is contributed by the difference between patients under 50 years of age. In the non-warfarin group, it requires an age gap of at least 20 years for the difference in fibrinogen to be statistically significant but in the warfarin group, it only requires an age gap of ten years (p&lt;0.05). Both Linear Regression and Cross Tabulation indicate that the relationship between fibrinogen and age does not vary whether or not the patient is on warfarin. These also show that the effect of age on fibrinogen is not affected by warfarin treatment. Conclusion: Differences or correlations detected in this analysis are of statistical significance but not necessarily clinically significant. Placing age and warfarin treatment in the same model shows that variations in fibrinogen have to be explained by other factors (e.g. technical) not included in the study as only 12% of the error in predicting fibrinogen levels can be reduced by knowing both the age and status of warfarin treatment in individual patients.

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