scholarly journals Rates of emergence of HIV drug resistance in resource-limited settings: a systematic review

2012 ◽  
Vol 18 (1) ◽  
pp. 115-123 ◽  
Author(s):  
Kathryn M Stadeli ◽  
Douglas D Richman
Keyword(s):  
Systematic Review ◽  
Drug Resistance ◽  
Resource Limited Settings ◽  
Hiv Drug Resistance ◽  
Resource Limited

scholarly journals HIV drug resistance surveillance for prioritizing treatment in resource-limited settings

AIDS ◽  
2007 ◽  
Vol 21 (8) ◽  
pp. 973-982 ◽  
Author(s):  
Rochelle P Walensky ◽  
Milton C Weinstein ◽  
Yazdan Yazdanpanah ◽  
Elena Losina ◽  
Lauren M Mercincavage ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Resource Limited Settings ◽  
Hiv Drug Resistance ◽  
Resource Limited

scholarly journals Emergence of HIV Drug Resistance During First- and Second-Line Antiretroviral Therapy in Resource-Limited Settings

2013 ◽  
Vol 207 (suppl_2) ◽  
pp. S49-S56 ◽  
Author(s):  
Mina C. Hosseinipour ◽  
Ravindra K Gupta ◽  
Gert Van Zyl ◽  
Joseph J. Eron ◽  
Jean B. Nachega
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
Second Line ◽  
Resource Limited Settings ◽  
Hiv Drug Resistance ◽  
Resource Limited ◽  
Second Line Antiretroviral Therapy

scholarly journals Prevalence and Correlates of Pre-Treatment HIV Drug Resistance among HIV-Infected Children in Ethiopia

Viruses ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 877 ◽  
Author(s):  
Birkneh Tilahun Tadesse ◽  
Olivia Tsai ◽  
Adugna Chala ◽  
Tolossa Eticha Chaka ◽  
Temesgen Eromo ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Reverse Transcriptase ◽  
Hiv Treatment ◽  
Hiv Care ◽  
Virologic Suppression ◽  
Reverse Transcriptase Inhibitors ◽  
Resource Limited Settings ◽  
Nucleoside Reverse Transcriptase Inhibitors ◽  
Hiv Drug Resistance ◽  
Resource Limited

Pediatric human immunodeficiency virus (HIV) care in resource-limited settings remains a major challenge to achieving global HIV treatment and virologic suppression targets, in part because the administration of combination antiretroviral therapies (cART) is inherently complex in this population and because viral load and drug resistance genotyping are not routinely available in these settings. Children may also be at elevated risk of transmission of drug-resistant HIV as a result of suboptimal antiretroviral administration for prevention of mother-to-child transmission. We investigated the prevalence and the correlates of pretreatment HIV drug resistance (PDR) among HIV-infected, cART-naive children in Ethiopia. We observed an overall PDR rate of 14%, where all cases featured resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs): ~9% of participants harbored resistance solely to NNRTIs while ~5% harbored resistance to both NNRTIs and nucleoside reverse transcriptase inhibitors (NRTIs). No resistance to protease inhibitors was observed. No sociodemographic or clinical parameters were significantly associated with PDR, though limited statistical power is noted. The relatively high (14%) rate of NNRTI resistance in cART-naive children supports the use of non-NNRTI-based regimens in first-line pediatric treatment in Ethiopia and underscores the urgent need for access to additional antiretroviral classes in resource-limited settings.

scholarly journals Utilization of dried blood spot specimens can expedite nationwide surveillance of HIV drug resistance in resource-limited settings

PLoS ONE ◽  
2018 ◽  
Vol 13 (9) ◽  
pp. e0203296 ◽  
Author(s):  
Guoqing Zhang ◽  
Joshua DeVos ◽  
Sandra Medina-Moreno ◽  
Nicholas Wagar ◽  
Karidia Diallo ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Dried Blood Spot ◽  
Resource Limited Settings ◽  
Hiv Drug Resistance ◽  
Resource Limited ◽  
Nationwide Surveillance ◽  
Blood Spot

HIV Drug Resistance Testing in a Resource Limited Setting with High Viral Diversity: The First Twenty Eight Months Experience

2017 ◽  
Vol 15 (4) ◽  
Author(s):  
Elodie Teclaire Ngo-Malabo ◽  
Paul Alain Ngoupo ◽  
Serge Alain Sadeuh-Mba ◽  
Emmanuel Akongnwi ◽  
Robert Banaï ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Resource Limited Setting ◽  
Resistance Testing ◽  
Viral Diversity ◽  
Hiv Drug Resistance ◽  
Drug Resistance Testing ◽  
Resource Limited ◽  
Limited Setting
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