Looking for an Active Conformation of the Future HIV Type-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Giuseppe La Regina; Antonio Coluccia; Romano Silvestri

doi:10.3851/imp1607

Looking for an Active Conformation of the Future HIV Type-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Antiviral Chemistry and Chemotherapy ◽

10.3851/imp1607 ◽

2010 ◽

Vol 20 (6) ◽

pp. 213-237 ◽

Cited By ~ 42

Author(s):

Giuseppe La Regina ◽

Antonio Coluccia ◽

Romano Silvestri

Keyword(s):

Reverse Transcriptase ◽

Active Conformation ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

The Future ◽

Hiv Type 1

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Binding Modes of Two Novel Non-Nucleoside Reverse Transcriptase Inhibitors, YM-215389 and YM-228855, to HIV Type-1 Reverse Transcriptase

Antiviral Chemistry and Chemotherapy ◽

10.1177/095632020801900304 ◽

2008 ◽

Vol 19 (3) ◽

pp. 133-141 ◽

Cited By ~ 2

Author(s):

Eiichi Kodama ◽

Masaya Orita ◽

Naoyuki Masuda ◽

Osamu Yamamoto ◽

Masahiro Fujii ◽

...

Keyword(s):

Reverse Transcriptase ◽

Binding Modes ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Hiv Type 1

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Current Status of the Non-nucleoside Reverse Transcriptase Inhibitors of Human Immunodeficiency Virus Type 1

Current Topics in Medicinal Chemistry ◽

10.2174/1568026043388420 ◽

2004 ◽

Vol 4 (9) ◽

pp. 921-944 ◽

Cited By ~ 87

Author(s):

J. Balzarini

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Current Status ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Immunodeficiency Virus

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Human Immunodeficiency Virus Type 1 Non-Nucleoside Reverse Transcriptase Inhibitors

Antiviral Research ◽

10.1128/9781555815493.ch3 ◽

2014 ◽

pp. 33-50 ◽

Cited By ~ 1

Author(s):

Dirk Jochmans ◽

Johan Vingerhoets ◽

Eric Arnoult ◽

Luc Geeraert ◽

Jérôme Guillemont

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Immunodeficiency Virus

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Safety and Antiviral Activity at 48 Weeks of Lopinavir/Ritonavir plus Nevirapine and 2 Nucleoside Reverse‐Transcriptase Inhibitors in Human Immunodeficiency Virus Type 1–Infected Protease Inhibitor–Experienced Patients

The Journal of Infectious Diseases ◽

10.1086/339014 ◽

2002 ◽

Vol 185 (5) ◽

pp. 599-607 ◽

Cited By ~ 110

Author(s):

Constance A. Benson ◽

Steven G. Deeks ◽

Scott C. Brun ◽

Roy M. Gulick ◽

Joseph J. Eron ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Antiviral Activity ◽

Protease Inhibitor ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Immunodeficiency Virus

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Novel 1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine Derivatives as Non-Nucleoside Reverse Transcriptase Inhibitors That Inhibit Human Immunodeficiency Virus Type 1 Replication

Journal of Medicinal Chemistry ◽

10.1021/jm9802012 ◽

1998 ◽

Vol 41 (21) ◽

pp. 4109-4117 ◽

Cited By ~ 27

Author(s):

Esther Arranz ◽

Juan A. Díaz ◽

Simon T. Ingate ◽

Myriam Witvrouw ◽

Christophe Pannecouque ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Immunodeficiency Virus

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Progress of Bis(heteroaryl)piperazines (BHAPs) as Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) against Human Immunodeficiency Virus Type 1 (HIV-1)

Mini-Reviews in Medicinal Chemistry ◽

10.2174/138955710791112578 ◽

2010 ◽

Vol 10 (1) ◽

pp. 62-72 ◽

Cited By ~ 4

Author(s):

Hui Xu

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Immunodeficiency Virus ◽

Hiv 1

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Resistance to Nonnucleoside Reverse-Transcriptase Inhibitors and Prevalence of HIV Type 1 Non-B Subtypes Are Increasing among Persons with Recent Infection in Spain

Clinical Infectious Diseases ◽

10.1086/496982 ◽

2005 ◽

Vol 41 (9) ◽

pp. 1350-1354 ◽

Cited By ~ 42

Author(s):

C. d. Mendoza ◽

C. Rodriguez ◽

J. Colomina ◽

C. Tuset ◽

F. Garcia ◽

...

Keyword(s):

Reverse Transcriptase ◽

Reverse Transcriptase Inhibitors ◽

Recent Infection ◽

Nonnucleoside Reverse Transcriptase Inhibitors ◽

Hiv Type 1

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Deconstruction of Non-Nucleoside Reverse Transcriptase Inhibitors of Human Immunodeficiency Virus Type 1 for Exploration of the Optimization Landscape of Fragments

Journal of Medicinal Chemistry ◽

10.1021/jm101052g ◽

2011 ◽

Vol 54 (3) ◽

pp. 709-718 ◽

Cited By ~ 15

Author(s):

Peter Brandt ◽

Matthis Geitmann ◽

U. Helena Danielson

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Immunodeficiency Virus

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Long-Term Exposure of HIV Type 1-Infected Cell Cultures to Combinations of the Novel Quinoxaline GW420867X with Lamivudine, Abacavir, and a Variety of Nonnucleoside Reverse Transcriptase Inhibitors

AIDS Research and Human Retroviruses ◽

10.1089/088922200308936 ◽

2000 ◽

Vol 16 (6) ◽

pp. 517-528 ◽

Cited By ~ 34

Author(s):

Jan Balzarini ◽

Erik De Clercq ◽

An Carbonez ◽

Vikki Burt ◽

Jörg-Peter Kleim

Keyword(s):

Infected Cell ◽

Reverse Transcriptase ◽

Cell Cultures ◽

The Novel ◽

Reverse Transcriptase Inhibitors ◽

Nonnucleoside Reverse Transcriptase Inhibitors ◽

Hiv Type 1

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Short Communication: Lamivudine Resistance of HIV Type 1 Does Not Delay Development of Resistance to Nonnucleoside HIV Type 1-Specific Reverse Transcriptase Inhibitors as Compared with Wild-Type HIV Type 1

AIDS Research and Human Retroviruses ◽

10.1089/aid.1998.14.249 ◽

1998 ◽

Vol 14 (3) ◽

pp. 249-253 ◽

Cited By ~ 22

Author(s):

HEIDI JONCKHEERE ◽

MYRIAM WITVROUW ◽

ERIK DE CLERCQ ◽

JOZEF ANNÉ

Keyword(s):

Reverse Transcriptase ◽

Short Communication ◽

Wild Type ◽

Reverse Transcriptase Inhibitors ◽

Lamivudine Resistance ◽

Development Of Resistance ◽

Hiv Type 1

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