Anti-oxidant Property and Tyrosinase Inhibition Activity of Various Extracts from Plants in Compositae Plants

2008 ◽  
Vol 51 (4) ◽  
pp. 321-328 ◽  
Author(s):  
Jeong Ran Kang
Keyword(s):  
Inhibition Activity ◽  
Tyrosinase Inhibition ◽  
Anti Oxidant ◽  
Compositae Plants

scholarly journals Cylindromicin from Arctic-Derived Fungus Tolypocladium sp. SCSIO 40433

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1080
Author(s):  
Imran Khan ◽  
Jing Peng ◽  
Zhuangjie Fang ◽  
Wei Liu ◽  
Wenjun Zhang ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Nuclear Overhauser Effect ◽  
Inhibition Activity ◽  
Tyrosinase Inhibition ◽  
Bioactive Natural Products ◽  
Chemical Structures ◽  
Overhauser Effect ◽  
Spectroscopic Analyses ◽  
Potential Resource ◽  
Nuclear Overhauser

The fungus strain SCSIO 40433 was isolated from an Arctic-derived glacier sediment sample and characterized as Tolypocladium cylindrosporum. A new compound, cylindromicin (1), and seven known secondary metabolites (2–8) were isolated from this strain. The chemical structures of these compounds were elucidated by comprehensive spectroscopic analyses. Cylindromicin (1) featured a 3,4-dihydro-2H-pyran skeleton. The absolute configuration of compound 1 was assigned via interpretation of key Nuclear Overhauser Effect Spectroscopy (NOESY) correlations and Electronic Circular Dichroism (ECD) calculation. Cylindromicin (1) exhibited significant tyrosinase inhibition activity. This study highlights Polar fungi as a potential resource for new bioactive natural products.

scholarly journals Valonea Tannin: Tyrosinase Inhibition Activity, Structural Elucidation and Insights into the Inhibition Mechanism

Molecules ◽  
2021 ◽  
Vol 26 (9) ◽  
pp. 2747
Author(s):  
Jiaman Liu ◽  
Yuqing Liu ◽  
Xiaofeng He ◽  
Bo Teng ◽  
Jacqui M. McRae
Keyword(s):  
Molecular Weight ◽  
Structure Function ◽  
Hydrophobic Interactions ◽  
Average Molecular Weight ◽  
Commercial Application ◽  
Inhibition Mechanism ◽  
Resonance Spectroscopy ◽  
Inhibition Activity ◽  
Tyrosinase Inhibition ◽  
Function Activity

Valonea tannin is a natural product readily extracted from acorn shells that has been suggested to have potential skin whitening properties. This study investigated the tyrosinase inhibition activity of extracted valonea tannin and the associated structure–function activity. Nuclear magnetic resonance spectroscopy and molecular weight analysis with gel permeation chromatography revealed that valonea tannin could be characterized as a hydrolysable tannin with galloyl, hexahydroxydiphenoyl and open formed-glucose moieties and an average molecular weight of 3042 ± 15 Da. Tyrosinase inhibition assays demonstrated that valonea tannin was 334 times more effective than gallic acid and 3.4 times more effective than tannic acid, which may relate to the larger molecular size. Kinetic studies of the inhibition reactions indicated that valonea tannin provided tyrosinase inhibition through mixed competitive–uncompetitive way. Stern–Volmer fitted fluorescence quenching analysis, isothermal titration calorimetry analysis and in silico molecule docking showed valonea tannin non-selectively bound to the surface of tyrosinase via hydrogen bonds and hydrophobic interactions. Inductively coupled plasma-optical emission spectroscopy and free radical scavenging assays indicated the valonea tannin had copper ion chelating and antioxidant ability, which may also contribute to inhibition activity. These results demonstrated the structure–function activity of valonea tannin as a highly effective natural tyrosinase inhibitor that may have commercial application in dermatological medicines or cosmetic products.

Synthesis and tyrosinase inhibition activity of trans -stilbene derivatives

2016 ◽  
Vol 64 ◽  
pp. 97-102 ◽  
Author(s):  
Tabasum Ismail ◽  
Syed Shafi ◽  
Jada Srinivas ◽  
Dhiman Sarkar ◽  
Yasrib Qurishi ◽  
...  
Keyword(s):  
Inhibition Activity ◽  
Tyrosinase Inhibition ◽  
Trans Stilbene ◽  
Stilbene Derivatives

Mushroom Tyrosinase Inhibition Activity of Some Chromones.

ChemInform ◽  
2010 ◽  
Vol 33 (35) ◽  
pp. 134-134
Author(s):  
Long Zhu Piao ◽  
Hyang Rae Park ◽  
Yun Kyung Park ◽  
Seung Ki Lee ◽  
Jeong Hill Park ◽  
...  
Keyword(s):  
Mushroom Tyrosinase ◽  
Inhibition Activity ◽  
Tyrosinase Inhibition

scholarly journals Mushroom Tyrosinase Inhibition Activity of Some Chromones

2002 ◽  
Vol 50 (3) ◽  
pp. 309-311 ◽  
Author(s):  
Long Zhu Piao ◽  
Hyang Rae Park ◽  
Yun Kyung Park ◽  
Seung Ki Lee ◽  
Jeong Hill Park ◽  
...  
Keyword(s):  
Mushroom Tyrosinase ◽  
Inhibition Activity ◽  
Tyrosinase Inhibition

Free Radical Scavenging and Tyrosinase Inhibition Activity of Physic Nut (Jatropha curcas Linn.) Seed Oil Entrapped in Niosomes

2011 ◽  
Vol 7 (5) ◽  
pp. 825-829
Author(s):  
Aranya Manosroi ◽  
Korawinwich Boonpisuttinant ◽  
Supanida Winitchai ◽  
Worapaka Manosroi ◽  
Jiradej Manosroi
Keyword(s):  
Free Radical ◽  
Jatropha Curcas ◽  
Seed Oil ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Inhibition Activity ◽  
Physic Nut ◽  
Tyrosinase Inhibition
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