scholarly journals Laboratory approach for detection of Non-invasive fungal Rhinosinusitis: A case-control study

10.3823/782 ◽  
2016 ◽  
Author(s):  
Nissreen E. ELBadawy ◽  
Takwa E. Meawed ◽  
Mohammad Waheed El-Anwar
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Non Invasive ◽  
Fungal Rhinosinusitis ◽  
Control Study ◽  
Invasive Fungal Rhinosinusitis

scholarly journals Acute versus Chronic Invasive Fungal Rhinosinusitis: A Case-Control Study

2012 ◽  
Vol 5 ◽  
pp. IDRT.S9818 ◽  
Author(s):  
Patorn Piromchai ◽  
Sanguansak Thanaviratananich
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Immunocompromised Patients ◽  
Fungal Rhinosinusitis ◽  
Sinus Wall ◽  
Significant Difference ◽  
Mucosal Necrosis ◽  
Control Study ◽  
Invasive Fungal Rhinosinusitis ◽  
Chronic Invasive

Introduction Invasive fungal rhinosinusitis is a challenging condition that can be found mostly in immunocompromised patients. Failure to diagnose and treat this entity promptly usually results in rapid progression and death. The purpose of this study was to determine clinical presentation, complication and morbidity in patients with acute versus chronic invasive fungal rhinosinusitis. Setting and design Case-control study at Srinagarind Hospital, Khon Kaen University between January 1998 and May 2008. Methods The patient's data with the diagnosis of invasive fungal rhinosinusitis was included. Demographic data, underlying diseases, presenting symptoms, histologic sinonasal tissue evaluations, sinonasal tissue cultures, CT scan findings, surgical interventions, morbidity, and mortality were collected. Results Sixty-five patients were diagnosed as invasive fungal rhinosinusitis between January 1998 and May 2008. The data of six patients were unable to obtain. Fifty-nine patients were included in this study. Patients with immunocompromised status have significant greater risk for acute than chronic IFS, OR = 6.5 ( P = 0.004). Patients with mucosal necrosis have the significant higher risk for acute IFS, OR = 5.5 ( P = 0.01). There was no significant difference in orbital complications proportion between acute and chronic invasive fungal rhinosinusitis, OR = 2.42 ( P = 0.15). Sinus wall erosion have found significantly in chronic IFS group, OR = 0.24 ( P = 0.02). The average hospital stayed was 30.58 ± 26.43 days with no difference between groups ( P = 0.50). Fourteen patients in acute IFS group were dead (31.11%) while all patients in chronic IFS group were survived. Conclusions Invasive fungal rhinosinusitis continues to present a challenge to the otolaryngologist. Acute IFS was found most commonly in immunocompromised patients. The most consistent finding of acute IFS was mucosal necrosis and black crust/debris. The CT finding of sinus wall erosion may help in diagnosis of chronic IFS.

scholarly journals Invasive Fungal Rhinosinusitis versus Bacterial Rhinosinusitis with Orbital Complications: A Case-Control Study

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Patorn Piromchai ◽  
Sanguansak Thanaviratananich
Keyword(s):  
Risk Factors ◽  
Mortality Rate ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Presenting Symptoms ◽  
Fungal Rhinosinusitis ◽  
Orbital Complications ◽  
Control Study ◽  
Invasive Fungal Rhinosinusitis

Background. Invasive fungal rhinosinusitis with orbital complications (IFSwOC) is a life-threatening condition. The incidence of mortality has been reported to be up to 80 percent. This study was conducted to determine the risk factors, presentations, clinical, and imaging findings that could help to manage this condition promptly.Methods. We conducted a case-control study of 100 patients suffering from rhinosinusitis with orbital complications. The risk factors, clinical presentations, radiological findings, medical and surgical managements, durations of hospital stay, and mortality rate data were collected.Results. Sixty-five patients were diagnosed with IFSwOC, while the other thirty-five patients composed the control group. The most important risk factor for IFSwOC was diabetes mellitus. Visual loss and diplopia were the significant symptom predictors. The significant clinical predictors were nasal crust, oculomotor nerve, and optic nerve involvement. The CT findings of IFSwOC were sinus wall erosion and hyperdensity lesions. The mortality rate was 25.71 percent in the IFSwOC group and 3.17 percent in the control group.Conclusions. Invasive fungal rhinosinusitis with orbital complications is symptomatic of a high mortality rate. The awareness of a patient’s risk factors, the presenting symptoms, signs of fungal invasion, and aggressive management will determine the success of any treatment procedures.

Acceptance of a new non-invasive fetal monitoring system and attitude for telemedicine approaches in obstetrics: a case–control study

2018 ◽  
Vol 298 (6) ◽  
pp. 1085-1093 ◽  
Author(s):  
Katharina Schramm ◽  
Florian Lapert ◽  
Juliane Nees ◽  
Carlijn Lempersz ◽  
S. Guid Oei ◽  
...  
Keyword(s):  
Monitoring System ◽  
Case Control Study ◽  
Fetal Monitoring ◽  
Case Control ◽  
Non Invasive ◽  
Control Study

548 A new non-invasive technique in primary sclerosing cholangitis (PSC): A case-control study

2004 ◽  
Vol 40 ◽  
pp. 161
Author(s):  
V. Macchi ◽  
E. Bezzon ◽  
A. Floreani ◽  
R. Pasini ◽  
P. Marchesi ◽  
...  
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Case Control Study ◽  
Case Control ◽  
Invasive Technique ◽  
Non Invasive ◽  
Control Study

scholarly journals The Copenhagen case-control study of bladder cancer: role of smoking in invasive and non-invasive bladder tumours.

1987 ◽  
Vol 41 (1) ◽  
pp. 30-36 ◽  
Author(s):  
O M Jensen ◽  
J Wahrendorf ◽  
M Blettner ◽  
J B Knudsen ◽  
B L Sorensen
Keyword(s):  
Bladder Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Non Invasive ◽  
Control Study ◽  
Bladder Tumours

scholarly journals Identifying Possible Hepatic Fibrosis of Hepatitis B Origin Using Non-invasive Markers: A Case-control Study in the South West Region of Cameroon

2019 ◽  
pp. 1-12
Author(s):  
Kukwah Anthony Tufon ◽  
Henry Dilonga Meriki ◽  
Kwenti Emmanuel Tebit ◽  
Teuwafeu Denis Georges ◽  
Nyeke James Tony ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Hepatitis B ◽  
Hepatic Fibrosis ◽  
Case Control Study ◽  
Case Control ◽  
Non Invasive ◽  
West Region ◽  
South West ◽  
Control Study ◽  
South West Region

Aim: HBV infection is known to cause liver fibrosis as well as some extrahepatic manifestations. We aimed at assessing hematological changes and identifying possible hepatic fibrosis of Hepatitis B origin using non-invasive markers (NIMs). Study Design: A hospital-based Case-control study Place and Duration of Study: Conducted at the Buea Regional Hospital, South West Region of Cameroon from February 2016 to December 2017 Methods: We enrolled HBV infected treatment naïve patients and “healthy” controls. All participants were subjected to alanine aminotransferase (ALT) and aspartate aminotransferase (AST) measurement, Full blood count (FBC), HBsAg, anti-HBc, HIV and HCV tests. Aspartate-platelet ratio index (APRI), fibrosis based on 4 factors (FIB-4), age-platelet index (API) and AST/ALT ratio (AAR) were generated from the test results. A questionnaire was administered to collect demographic data, alcohol consumption and history of liver/kidney disease or metabolic syndrome. Results: A total of 202 cases and 202 controls were enrolled. Hematocrit (HCT) was significantly higher (p<0.001) in cases than controls. The controls had significantly higher mean values for platelet (p=0.005), neutrophil (p=0.032) and number of individuals with AST/ALT ratio (AAR) ≥1. Liver fibrosis was significantly associated with cases than controls based on APRI (OR:6.06, CI:3.59-10.24), FIB-4 (OR:5.35, CI:2.75-10.39) and API (OR:8.02, CI:1.81-35.55). Among the HBV infected cases, 69 (34.2%), 36(17.8%) and 8(4.0%) had results indicative of fibrosis from at least 2, at least 3 and all 4 NIMs respectively. AAR detected possible fibrosis in 136 HBV infected cases of which up to 77 (56.6%) were not detected as fibrosis by the other NIMs. Conclusion: HBV infection affects neutrophil percentage, HCT, PLT, APRI, FIB-4 and API in our study population. AAR did not prove to be a reliable NIM. Using at least 3 NIMs for HBV infected patients can significantly scale up their reliability for determining liver fibrosis in clinical practice.

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