scholarly journals Colon Cancer: What's New?

2021 ◽  
pp. 12-16
Author(s):  
Stanley Kim
Keyword(s):  
Colorectal Cancer ◽  
Cancer Cells ◽  
Task Force ◽  
Screening Method ◽  
Cancer Society ◽  
Detection Rates ◽  
Genetic Characteristics ◽  
High Fiber ◽  
Fiber Diet ◽  
Standard Colonoscopy

Colorectal cancer is the third most common cancer. Standard colonoscopy is the first-tier screening method. However, other non-invasive tests have shown high cancer detection rates. The age when screening is started is controversial: the U.S. Preventive Service Task Force (USPSTF) and the American College of Physicians (ACP) recommend the starting age of 50 while the American Cancer Society (ACS) recommends 45. In 2021, the American College of Gastroenterology (ACG) revised the guideline of the first screening age from 45–years old to 50-years-old. A recent study confirmed that the risk of colorectal cancer is lowered by a high fiber diet, low red meat intake, and consumption of yogurt. The detection of specific molecular and genetic characteristics of each patient’s cancer cells is the utmost important component of precision medicine. Many biomarkers of cancer cells are discussed along with their inhibitors. A recent study showed that three-month adjuvant chemotherapy is not inferior to six-month chemotherapy

When to Stop Screening: A Review of Breast, Gynecologic, and Colorectal Cancer Screening in Women Over Age 65

2010 ◽  
Vol 11 (1) ◽  
pp. 48-57 ◽  
Author(s):  
Rebecca Bernstein ◽  
Daniel Dejoseph ◽  
Edward M. Buchanan
Keyword(s):  
Colorectal Cancer ◽  
Cancer Screening ◽  
Task Force ◽  
The United States ◽  
Screening Tests ◽  
Women Patients ◽  
Cancer Society ◽  
Screening Guidelines ◽  
Health Goals ◽  
Current Screening

Because age alone is not an indicator of health, there is no clear consensus among the various cancer screening guidelines on when to stop cancer screening. For breast, cervical, and colorectal cancer, there are recommended screening tests, while, for other gynecologic cancers, there are not. When discussing with older women patients when to stop cancer screening, we encourage practitioners to review the goals of the screening test, assess the health and functional status of the patient, and discuss her values and health goals. To facilitate this discussion, we review proposed frameworks for determining when to screen older patients for cancer. We also review the concepts of “well” and “frail” older adults. Finally, we review the current screening recommendations for breast, gynecological, and colorectal cancers, and the reasoning behind them, from the United States Preventative Screening Task Force, the American Cancer Society, the American College of Obstetricians and Gynecologists, and the American Geriatric Society.

Clinical features and survival among patients with standard-onset versus early-onset colorectal cancer by age groups.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 3614-3614
Author(s):  
Ana Acuna Villaorduna ◽  
Nishi Shah ◽  
Sanjay Goel
Keyword(s):  
Colorectal Cancer ◽  
Clinical Features ◽  
Early Onset ◽  
Task Force ◽  
Age Groups ◽  
Stage Iv ◽  
Early Screening ◽  
Cancer Society ◽  
Crc Screening ◽  
Early Onset Colorectal Cancer

3614 Background: Colorectal cancer (CRC) incidence is increasing in patients younger than 50 years old. Currently, there are discordant recommendations regarding CRC screening: while the American Cancer Society favors to start at age 45, the National Comprehensive Cancer Network and the US Preventive Task Force suggest starting at age 50. This study is aimed to compare the incidence, clinical characteristics and survival of patients diagnosed with standard-onset CRC (SO) versus early-onset colorectal cancer by age-groups. Methods: Patients diagnosed with CRC at ages older than 35 were identified using the SEER registry and categorized into four groups based on age at diagnosis. EO1 (35-39), EO2 (40-44), EO3 (45-49) and SO (>50) years, respectively. Incidence, clinical features and survival were compared among groups. Results: 178 678 patients were identified. 9.2% were diagnosed before 50 years. Of these, 1.4%, 2.8% and 5.1% were EO1, EO2 and EO3; respectively. Patients with early-onset CRC (EO) had higher frequency of Hispanics (13.9% vs. 8.4%, p<0.01), stage IV (24.8% vs. 17.3%, p<0.01), left-sided tumors (74.1% vs. 56.9%, p<0.01) and better survival compared to SO. Among EO groups, the frequency of poor/anaplastic grade was inversely proportional to age; stage IV was similar between EO2 and EO3 and lower in EO1. Black race, grade and stage were predictors of mortality for all EO groups; laterality was a mortality predictor in EO2 and EO3. Conclusions: EO-CRC and SO-CRC have different pathological features that should be considered for CRC screening. Higher rates of stage IV disease are encountered in patients between 40-49 years old; hence early screening should be considered. Given higher rates of left-sided tumors, sigmoidoscopy might be an adequate tool for most patients with EO-CRC. [Table: see text]

Guidelines for Colonoscopy Surveillance After Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society

2006 ◽  
Vol 130 (6) ◽  
pp. 1872-1885 ◽  
Author(s):  
Sidney J. Winawer ◽  
Ann G. Zauber ◽  
Robert H. Fletcher ◽  
Jonathon S. Stillman ◽  
Michael J. O’Brien ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Task Force ◽  
American Cancer Society ◽  
Cancer Society ◽  
The Us ◽  
Colonoscopy Surveillance

Revised Colorectal Screening Guidelines: Joint Effort of the American Cancer Society, U.S. Multisociety Task Force on Colorectal Cancer, and American College of Radiology

Radiology ◽  
2008 ◽  
Vol 248 (3) ◽  
pp. 717-720 ◽  
Author(s):  
Elizabeth G. McFarland ◽  
Bernard Levin ◽  
David A. Lieberman ◽  
Perry J. Pickhardt ◽  
C. Daniel Johnson ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Task Force ◽  
American Cancer Society ◽  
Joint Effort ◽  
Cancer Society ◽  
Screening Guidelines ◽  
Colorectal Screening
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