scholarly journals Global Neurodiverse Support Systems

The Physician ◽  
2020 ◽  
Vol 6 (3) ◽  
pp. 1-22
Author(s):  
Ritwika Roy ◽  
Shreya Jain
Keyword(s):  
Multidisciplinary Approach ◽  
Research Study ◽  
Support Systems ◽  
Community Based ◽  
Research Survey ◽  
System A ◽  
Low Levels ◽  
Identification Analysis ◽  
The Brain ◽  
Primary Research Study

Neurodiversity refers to the inherent differences in the structure and functioning of the brain causing neurological variations. These include but are not limited to Autism, ADHD, Learning disabilities, Tourette’s syndrome. However, the understanding of these conditions and the support available has considerable scope for improvement, and new advances are continually being made. This leads to a vast disparity in the support systems available for the neurodiverse community across different countries. This paper comprises of two parts; the first half includes an analysis of the global support systems for neurodiverse conditions based on the current research available for different regions; the second half includes a primary research study conducted supported by gap-identification analysis of Mumbai’s (India) neurodiverse support system. A set of suggestions is formulated based on observations such as the lack of a multidisciplinary approach, poor levels of coordination, low levels of inclusion in the education sector from the research survey, to improve the support provided to the neurodiverse community. Based on these evidence-based solutions further research can be conducted to mitigate the problems faced by the neurodiverse community and its coexisting support systems.

ADRENOCORTICAL FUNCTION IN PATIENTS WITH ACUTE SEVERE BRAIN AND PITUITARY LESION

1962 ◽  
Vol 40 (2) ◽  
pp. 254-262 ◽  
Author(s):  
H. H. Bassøe ◽  
R. Emberland ◽  
E. Glück ◽  
K. F. Støa
Keyword(s):  
Pituitary Gland ◽  
Adrenal Cortex ◽  
Artificial Ventilation ◽  
Practical Significance ◽  
Adrenocortical Function ◽  
The Third ◽  
Low Levels ◽  
Pituitary Lesion ◽  
Steroid Excretion ◽  
The Brain

ABSTRACT The steroid excretion and the plasma corticosteroids were investigated in three patients with necrosis of the brain and of the pituitary gland. The patients were kept alive by artificial ventilation. In two of the patients the neutral 17-ketosteroids and the 17-hydrocorticosteroids fell to extremely low levels. At the same time, the number of eosinophil cells showed a tendency to increase. Corticotrophin administered intravenously twice to the third patient had a stimulating effect on the adrenal cortex. The theoretical and practical significance of these findings is discussed.

Individual Uniqueness in the Neonatal Functional Connectome

2021 ◽  
Author(s):  
Qiushi Wang ◽  
Yuehua Xu ◽  
Tengda Zhao ◽  
Zhilei Xu ◽  
Yong He ◽  
...  
Keyword(s):  
Individual Differences ◽  
Individual Identification ◽  
Imaging Data ◽  
Functional Connectome ◽  
Middle Range ◽  
Human Connectome Project ◽  
The Individual ◽  
And Behavior ◽  
Identification Analysis ◽  
The Brain

Abstract The functional connectome is highly distinctive in adults and adolescents, underlying individual differences in cognition and behavior. However, it remains unknown whether the individual uniqueness of the functional connectome is present in neonates, who are far from mature. Here, we utilized the multiband resting-state functional magnetic resonance imaging data of 40 healthy neonates from the Developing Human Connectome Project and a split-half analysis approach to characterize the uniqueness of the functional connectome in the neonatal brain. Through functional connectome-based individual identification analysis, we found that all the neonates were correctly identified, with the most discriminative regions predominantly confined to the higher-order cortices (e.g., prefrontal and parietal regions). The connectivities with the highest contributions to individual uniqueness were primarily located between different functional systems, and the short- (0–30 mm) and middle-range (30–60 mm) connectivities were more distinctive than the long-range (>60 mm) connectivities. Interestingly, we found that functional data with a scanning length longer than 3.5 min were able to capture the individual uniqueness in the functional connectome. Our results highlight that individual uniqueness is present in the functional connectome of neonates and provide insights into the brain mechanisms underlying individual differences in cognition and behavior later in life.

scholarly journals Sex differences in neural correlates of common psychopathological symptoms in early adolescence

2021 ◽  
pp. 1-11
Author(s):  
Francesca Biondo ◽  
Charlotte Nymberg Thunell ◽  
Bing Xu ◽  
Congying Chu ◽  
Tianye Jia ◽  
...  
Keyword(s):  
Internalizing Symptoms ◽  
Grey Matter ◽  
Neural Correlates ◽  
Brain Regions ◽  
Female Adolescents ◽  
Grey Matter Volume ◽  
Community Based ◽  
Psychopathological Symptom ◽  
Strengths And Difficulties ◽  
The Brain

Abstract Background Sex-related differences in psychopathology are known phenomena, with externalizing and internalizing symptoms typically more common in boys and girls, respectively. However, the neural correlates of these sex-by-psychopathology interactions are underinvestigated, particularly in adolescence. Methods Participants were 14 years of age and part of the IMAGEN study, a large (N = 1526) community-based sample. To test for sex-by-psychopathology interactions in structural grey matter volume (GMV), we used whole-brain, voxel-wise neuroimaging analyses based on robust non-parametric methods. Psychopathological symptom data were derived from the Strengths and Difficulties Questionnaire (SDQ). Results We found a sex-by-hyperactivity/inattention interaction in four brain clusters: right temporoparietal-opercular region (p < 0.01, Cohen's d = −0.24), bilateral anterior and mid-cingulum (p < 0.05, Cohen's d = −0.18), right cerebellum and fusiform (p < 0.05, Cohen's d = −0.20) and left frontal superior and middle gyri (p < 0.05, Cohen's d = −0.26). Higher symptoms of hyperactivity/inattention were associated with lower GMV in all four brain clusters in boys, and with higher GMV in the temporoparietal-opercular and cerebellar-fusiform clusters in girls. Conclusions Using a large, sex-balanced and community-based sample, our study lends support to the idea that externalizing symptoms of hyperactivity/inattention may be associated with different neural structures in male and female adolescents. The brain regions we report have been associated with a myriad of important cognitive functions, in particular, attention, cognitive and motor control, and timing, that are potentially relevant to understand the behavioural manifestations of hyperactive and inattentive symptoms. This study highlights the importance of considering sex in our efforts to uncover mechanisms underlying psychopathology during adolescence.

Baraza as method: Adapting a traditional conversational space for data collection and pathways for change

2021 ◽  
pp. 147332502110293
Author(s):  
Laura A. Chubb ◽  
Christa B. Fouché ◽  
Karen Sadeh Kengah
Keyword(s):  
Data Collection ◽  
Research Study ◽  
Community Based Participatory Research ◽  
Ways Of Knowing ◽  
Indigenous Communities ◽  
Local Communities ◽  
Working Relationships ◽  
Community Based ◽  
Cultural Contexts ◽  
Context Specific

The call to decolonise research processes and knowledge produced through them has spawned a powerful shift in working relationships between community researchers and members of local communities. Adaptation of a traditional conversational space in a community-based participatory research study offers a context-specific example of a decolonising method for data collection and as pathways for change. This article reports on learnings encountered while adapting the space and highlights the relevance for other cultural contexts. We present principles to adapt traditional conversational spaces both for collecting data and as a means of working in partnership with indigenous communities to enable different ways of knowing and action.

Classification of EEG Mental Patterns by Using Two Scalp Electrodes and Mahalanobis Distance-Based Classifiers

2002 ◽  
Vol 41 (04) ◽  
pp. 337-341 ◽  
Author(s):  
F. Cincotti ◽  
D. Mattia ◽  
C. Babiloni ◽  
F. Carducci ◽  
L. Bianchi ◽  
...  
Keyword(s):  
Mahalanobis Distance ◽  
Brain Computer Interface ◽  
Computer Interface ◽  
Correct Classification ◽  
Interface Area ◽  
System A ◽  
The Brain ◽  
Full Covariance Matrix ◽  
Recording Electrodes

Summary Objectives: In this paper, we explored the use of quadratic classifiers based on Mahalanobis distance to detect mental EEG patterns from a reduced set of scalp recording electrodes. Methods: Electrodes are placed in scalp centro-parietal zones (C3, P3, C4 and P4 positions of the international 10-20 system). A Mahalanobis distance classifier based on the use of full covariance matrix was used. Results: The quadratic classifier was able to detect EEG activity related to imagination of movement with an affordable accuracy (97% correct classification, on average) by using only C3 and C4 electrodes. Conclusions: Such a result is interesting for the use of Mahalanobis-based classifiers in the brain computer interface area.

Facial Ganglia - Anatomy, Symptomatology of Lesions and Biological Relevance

2021 ◽  
Vol 53 ◽  
pp. 41-50
Author(s):  
Ilya Lebedev ◽  
Alexander Bragin ◽  
Yulia Boldyreva ◽  
Artem Borsukov ◽  
Alexander Tersenov ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Facial Pain ◽  
Multidisciplinary Approach ◽  
Human Life ◽  
Cranial Nerves ◽  
Living Organism ◽  
Sympathetic Ganglia ◽  
Historical Background ◽  
Brain And Spinal Cord ◽  
The Brain

The article summarizes information about the head ganglia (the sympathetic ganglia and in the sensory cranial nerves). Gives а brief historical background on the history issue and relevance of the topic. Characterized by each node with its topography and lesion clinic. The described process of treatment, and prospects for new therapies. Raised the issue of the significance of the defeat ganglia, namely, the suffering of the sick and forced treatment costs (due to the complex differential diagnosis). In a biological sense, pain first appears in chordates and during evolution, as well as transformations of the brain and spinal cord, it acquires new types, localization and significance for the performance of a living organism. And facial pain, being a nosology with a multidisciplinary approach in diagnosis and treatment, demonstrates both its complexity and importance in human life.

scholarly journals Active Citizens: Evaluation of a Community-Based Education Program

2019 ◽  
Vol 11 (3) ◽  
pp. 663 ◽  
Author(s):  
Petra Simonova ◽  
Jan Cincera ◽  
Roman Kroufek ◽  
Sarka Krepelkova ◽  
Andreas Hadjichambis
Keyword(s):  
School Environment ◽  
Design Research ◽  
Research Study ◽  
Mixed Design ◽  
Control Groups ◽  
Community Based ◽  
Community Based Education ◽  
The Mean ◽  
Group Interviews ◽  
The Impact

This study analyses the Active Citizens program conducted in seven Czech elementary schools in 2017/2018. The data were obtained in a mixed-design research study containing pre/post experimental/control groups (N = 114), eight focus groups with selected students (N = 56), and group interviews with teachers (N = 14). The mean age of the students was 13.8 years. The study focuses on the students’ and the teachers’ perception of the process, the program’s barriers and benefits, and on the impact of the program on the students’ self-efficacy and on perceived democratic school culture. The analysis revealed that while the participants felt empowered because of their experience, they started to perceive their school environment as less democratic than before the program. The program also likely influenced girls more than boys as the latter seem to have been unaffected. Finally, the implications of the findings for the practice are discussed.

scholarly journals THE VISUAL SYSTEM: A "CHICKEN AND EGG" PROBLEM SOLVED

2009 ◽  
Vol 05 (01) ◽  
pp. 115-121
Author(s):  
ANDREW R. PARKER ◽  
H. JOHN CAULFIELD
Keyword(s):  
Visual System ◽  
Neural Plasticity ◽  
Neural Circuit ◽  
Process Data ◽  
System A ◽  
New Information ◽  
The Brain

"What comes first: the chicken or the egg?" Eyes and vision were a great concern for Darwin. Recently, religious fundamentalists have started to attack evolution on the grounds that this is a chicken and egg problem. How could eyes improve without the brain module to use the new information that eye provides? But how could the brain evolve a neural circuit to process data not available to it until a new eye capability emerges? We argue that neural plasticity in the brain allows it to make use of essentially any useful information the eye can produce. And it does so easily within the animal's lifetime. Richard Gregory suggested something like this 40 years ago. Our work resolves a problem with his otherwise-insightful work.

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