scholarly journals Mortality from Pulmonary Embolism by Clinical Severity

The Physician ◽  
2020 ◽  
Vol 6 (2) ◽  
Author(s):  
Arushi Asthana ◽  
Niladri Konar ◽  
Indranil Chakravorty

Aim: To report all-cause and PE related short term mortality by clinical severity of PE and to identify any missed opportunities for thrombolysis. Background: Mortality related to pulmonary embolism varies widely in the reported literature even for the same clinical severity category of PE. Method: Electronic medical records of all patients presenting to a large tertiary care teaching hospital in London, between October 1, 2018, and January 16, 2020, who had a discharge diagnosis of acute pulmonary embolism were reviewed retrospectively. Results: There was no PE related mortality in the low-risk PE group. There was one PE related death in the submassive PE group (1.47% mortality on day 14 and day 30).  Massive PE was associated with a 29.4% PE related mortality short-term mortality.

1996 ◽  
Vol 3 (4) ◽  
pp. 235-240 ◽  
Author(s):  
Rafael E de la Hoz ◽  
Shizu Hayashi ◽  
Darrel Cook ◽  
Christopher Sherlock ◽  
James C Hogg

OBJECTIVE:To investigate the occurrence of cytomegalovirus (CMV) pneumonitis in the setting of human immunodeficiency virus (HIV) infection and whether the presence of CMV as copathogen is associated with increased clinical severity or short term mortality in patients withPneumocystis cariniipneumonia.DESIGN:Retrospective cohort study.SETTING:Tertiary care university hospital.PATIENTS:One-hundred and fourteen HIV-infected homosexual men with pneumonia, followed for a minimum of four weeks.MEASUREMENTS:Clinical indicators of severity of pneumonia, microbiology of bronchoalveolar fluid and relative risk of short term mortality.RESULTS:Only two cases of CMV pneumonitis were found, one together withP carinii. However, 45 of the 86 patients withP cariniipneumonia were co-infected with CMV. No difference in clinical severity was detected between patients co-infected withP cariniiand CMV and those withP cariniialone. The relative risk of short term mortality was 3.64 (95% CI 0.82 to 16.18), in patients with co-infection compared with those withP cariniialone. The risk reached statistical significance for patients with earlier stages of HIV infection.CONCLUSIONS:CMV pneumonitis occurs rarely in HIV-infected patients, while CMV co-infection occurs in at least 50% of the cases ofP cariniipneumonia. Although no difference in clinical severity was detected, this study suggests that short term mortality fromP cariniipneumonia may be increased by CMV co-infection, particularly in patients with earlier stages of the disease.


TH Open ◽  
2021 ◽  
Vol 05 (01) ◽  
pp. e66-e72
Author(s):  
Lisette F. van Dam ◽  
Lucia J. M. Kroft ◽  
Menno V. Huisman ◽  
Maarten K. Ninaber ◽  
Frederikus A. Klok

Abstract Background Computed tomography pulmonary angiography (CTPA) is the imaging modality of choice for the diagnosis of acute pulmonary embolism (PE). With computed tomography pulmonary perfusion (CTPP) additional information on lung perfusion can be assessed, but its value in PE risk stratification is unknown. We aimed to evaluate the correlation between CTPP-assessed perfusion defect score (PDS) and clinical presentation and its predictive value for adverse short-term outcome of acute PE. Patients and Methods This was an exploratory, observational study in 100 hemodynamically stable patients with CTPA-confirmed acute PE in whom CTPP was performed as part of routine clinical practice. We calculated the difference between the mean PDS in patients with versus without chest pain, dyspnea, and hemoptysis and 7-day adverse outcome. Multivariable logistic regression analysis and likelihood-ratio test were used to assess the added predictive value of PDS to CTPA parameters of right ventricle dysfunction and total thrombus load, for intensive care unit admission, reperfusion therapy and PE-related death. Results We found no correlation between PDS and clinical symptoms. PDS was correlated to reperfusion therapy (n = 4 with 16% higher PDS, 95% confidence interval [CI]: 3.5–28%) and PE-related mortality (n = 2 with 22% higher PDS, 95% CI: 4.9–38). Moreover, PDS had an added predictive value to CTPA assessment for PE-related mortality (from Chi-square 14 to 19, p = 0.02). Conclusion CTPP-assessed PDS was not correlated to clinical presentation of acute PE. However, PDS was correlated to reperfusion therapy and PE-related mortality and had an added predictive value to CTPA-reading for PE-related mortality; this added value needs to be demonstrated in larger studies.


2018 ◽  
Vol 66 (3) ◽  
pp. 185-196
Author(s):  
Şehnaz Olgun Yıldızeli ◽  
Umut Sabri Kasapoğlu ◽  
Hüseyin Arıkan ◽  
Canan Çimşit ◽  
Nuri Çagatay Çimşit ◽  
...  

2013 ◽  
Vol 84 (1) ◽  
pp. 62 ◽  
Author(s):  
Yun-Ju Cho ◽  
So-My Koo ◽  
Duk Won Bang ◽  
Ki-Up Kim ◽  
Soo-taek Uh ◽  
...  

2018 ◽  
Vol 54 ◽  
pp. 27-33 ◽  
Author(s):  
Loris Roncon ◽  
Marco Zuin ◽  
Franco Casazza ◽  
Cecilia Becattini ◽  
Claudio Bilato ◽  
...  

Author(s):  
Ana Jaureguizar Oriol ◽  
Pedro Ruiz Artacho ◽  
Deisy Diana Barrios Barreto ◽  
Raquel Morillo Guerrero ◽  
Beatriz Martín García ◽  
...  

Author(s):  
Foteini Malli ◽  
George Vavougios ◽  
Fotini Bardaka ◽  
Konstantinos Gourgoulianis ◽  
Zoe Daniil

SICOT-J ◽  
2018 ◽  
Vol 4 ◽  
pp. 26 ◽  
Author(s):  
Gaston Camino Willhuber ◽  
Joaquin Stagnaro ◽  
Matias Petracchi ◽  
Agustin Donndorff ◽  
Daniel Godoy Monzon ◽  
...  

Introduction: Registration of adverse events following orthopedic surgery has a critical role in patient safety and has received increasing attention. The purpose of this study was to determine the prevalence and severity of postoperative complications in the department of orthopedic unit in a tertiary hospital. Methods: A retrospective review from the postoperative complication registry of a cohort of consecutive patients operated in the department of orthopedic surgery from May 2015 to June 2016 was performed. Short-term complications (3 months after surgery), age gender, types of surgery (elective, scheduled urgency, non-scheduled urgency, and emergency), operative time, surgical start time (morning, afternoon or evening), American Society of Anesthesiologists score and surgeon's experience were assessed. Complications were classified based on their severity according to Dindo-Clavien system: Grade I complications do not require alterations in the postoperative course or additional treatment; Grade II complications require pharmacological treatment; Grade III require surgical, endoscopic, or radiological interventions without (IIIa) or with (IIIb) general anesthesia; Grade IV are life-threatening with single (IVa) or multi-organ (IVb) dysfunction(s), and require ICU management; and Grade V result in death of the patient. Complications were further classified in minor (Dindo I, II, IIIa) and major (Dindo IIIb, IVa, IVb and V), according to clinical severity. Results: 1960 surgeries were performed. The overall 90-day complication rate was 12.7% (249/1960). Twenty-three complications (9.2 %) were type I, 159 (63.8%) type II, 9 (3.6%) type IIIa, 42 (16.8%) type IIIb, 7 (2.8%) type IVa and 9 (3.6%) were grade V according to Dindo-Clavien classification (DCC). The most frequent complication was anemia that required blood transfusion (27%) followed by wound infection (15.6%) and urinary tract infection (6%). Discussion: The overall complication rate after orthopedic surgery in our department was 12.7%. The implementation of the DCC following orthopedic surgery was an important tool to measure the standard of care.


2014 ◽  
Vol 134 (2) ◽  
pp. 326-330 ◽  
Author(s):  
Roberto Castelli ◽  
Paolo Bucciarelli ◽  
Fernando Porro ◽  
Federica Depetri ◽  
Massimo Cugno

Radiology ◽  
2012 ◽  
Vol 265 (1) ◽  
pp. 283-293 ◽  
Author(s):  
Alessandro Furlan ◽  
Ayaz Aghayev ◽  
Chung-Chou H. Chang ◽  
Amol Patil ◽  
Kyung Nyeo Jeon ◽  
...  

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