scholarly journals To Develop a Non-invasive Technique

The Physician ◽  
2019 ◽  
Vol 6 (1) ◽  
pp. c3
Author(s):  
Kshama Rahul Joshi ◽  
Haris Pervez ◽  
Antonia Pena-Fernandez
Keyword(s):  
Type 2 Diabetes ◽  
Three Dimensional ◽  
Invasive Technique ◽  
Effect Relationship ◽  
Cause And Effect ◽  
Non Invasive

A study was designed to understand a three-dimensional cause and effect relationship among ethnicity-based diet, relevant macro, and micro-nutrients obtained from the diet, and prevalence of type 2 diabetes.

scholarly journals Serum Anti-Collagen IV IgM and IgG Antibodies as Indicators of Low Vascular Turnover of Collagen IV in Patients with Long-Term Complications of Type 2 Diabetes

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 900
Author(s):  
Krasimir Kostov ◽  
Alexander Blazhev
Keyword(s):  
Type 2 Diabetes ◽  
Serum Levels ◽  
Vascular Wall ◽  
Collagen Iv ◽  
Collagen Type Iv ◽  
Non Invasive ◽  
Type Iv ◽  
Antibody Levels

Thickening of the vascular basement membrane (BM) is a fundamental structural change in the small blood vessels in diabetes. Collagen type IV (CIV) is a major component of the BMs, and monitoring the turnover of this protein in type 2 diabetes (T2D) can provide important information about the mechanisms of vascular damage. The aim of the study was through the use of non-invasive biomarkers of CIV (autoantibodies, derivative peptides, and immune complexes) to investigate vascular turnover of CIV in patients with long-term complications of T2D. We measured serum levels of these biomarkers in 59 T2D patients with micro- and/or macrovascular complications and 20 healthy controls using an ELISA. Matrix metalloproteinases-2 and -9 (MMP-2 and MMP-9) were also tested. In the T2D group, significantly lower levels of CIV markers and significantly higher levels of MMP-2 and MMP-9 were found compared to controls. A significant positive correlation was found between IgM antibody levels against CIV and MMP-2. These findings suggest that vascular metabolism of CIV is decreased in T2D with long-term complications and show that a positive linear relationship exists between MMP-2 levels and CIV turnover in the vascular wall.

scholarly journals Non‐invasive assessment of temporal changes in myocardial microvascular function in persons with type 2 diabetes and healthy controls

2021 ◽  
Author(s):  
Ida K. B. Rasmussen ◽  
Philip Hasbak ◽  
Bernt J. Scholten ◽  
Jens C. Laursen ◽  
Emilie H. Zobel ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Temporal Changes ◽  
Microvascular Function ◽  
Healthy Controls ◽  
Non Invasive

scholarly journals Type 2 diabetes and viral infection; cause and effect of disease

2021 ◽  
Vol 172 ◽  
pp. 108637
Author(s):  
Tamara Turk Wensveen ◽  
Dora Gašparini ◽  
Dario Rahelić ◽  
Felix M. Wensveen
Keyword(s):  
Type 2 Diabetes ◽  
Viral Infection ◽  
Cause And Effect
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