Hodgkin Lymphoma Presenting with Various Immunologic Abnormalities, Including Autoimmune Hepatitis, Hashimoto's Thyroiditis, Autoimmune Hemolytic Anemia, and Immune Thrombocytopenia

2008 ◽  
Vol 8 (1) ◽  
pp. 62-64 ◽  
Author(s):  
Takayuki Saitoh ◽  
Takafumi Matsushima ◽  
Yasuyuki Saito ◽  
Arito Yamane ◽  
Akihiko Yokohama ◽  
...  
2012 ◽  
Vol 34 (4) ◽  
pp. 280-282 ◽  
Author(s):  
Valerio Cecinati ◽  
Fulvia Brugnoletti ◽  
Mariella D’Angiò ◽  
Maria Chiara De Nicolò ◽  
Annalisa De Vellis ◽  
...  

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Anup J. Devasia ◽  
Raveen Stephen Stallon Illangeswaran ◽  
Infencia Xavier Raj ◽  
Biju George ◽  
Poonkuzhali Balasubramanian

AbstractObjectivesAzathioprine (AZA) is a commonly used immunosuppressant in patients with autoimmune diseases. The toxic side effect to AZA (myelosuppression, hair loss, and oral ulcers) are highly unpredictable which can be life threatening if not identified earlier and dose adjustments made or the drug is withdrawn.Case presentationHere we report a case series of five patients with severe toxicity while on treatment with AZA for autoimmune hemolytic anemia (n=1) and Immune thrombocytopenia (n=4). The common thiopurine methyltransferase (TPMT) variants (TPMT*2, *3A, *3B) were not present in these patients. However, all these patients had the NUDT15 415C>T variant that has been reported to explain serious toxicity to thioguanine in Asian patients.ConclusionsOur report suggests pre-emptive genotype-based dosing of AZA could reduce adverse toxicity and hence better outcome.


Thyroid ◽  
2004 ◽  
Vol 14 (8) ◽  
pp. 631-634 ◽  
Author(s):  
Mario Salvi ◽  
Guia Vannucchi ◽  
Francesco Sbrozzi ◽  
Alessandra Bottari Del Castello ◽  
Alessandra Carnevali ◽  
...  

Thyroid ◽  
2007 ◽  
Vol 17 (12) ◽  
pp. 1307-1307 ◽  
Author(s):  
T. Amenduni ◽  
P. Bellitti ◽  
A. Carbone ◽  
D. De Sanctis ◽  
E.V. Santospirito ◽  
...  

2021 ◽  
Vol 16 (2) ◽  
pp. 40-47
Author(s):  
I. S. Piskunova ◽  
T. N. Moiseeva ◽  
L. S. Al-Radi ◽  
L. V. Plastinina ◽  
S. R. Goryacheva

Cytopenia commonly occurs in case of chronic lymphocytic leukemia. It can either precede the diagnosis of chronic lymphocytic leukemia or appear at any time during the disease. Autoimmune hemolytic anemia, immune thrombocytopenia, and partial red cell aplasia are most often found among cytopenias in chronic lymphocytic leukemia. At the same time, the development of cytopenia may be associated with the displacement of normal hematopoiesis cells by tumor lymphocytes. It is very important to accurately diagnose and identify the cause of cytopenia in chronic lymphocytic leukemia, since the prognosis and therapy differ significantly.


2016 ◽  
Vol 6 ◽  
pp. S94
Author(s):  
Indrajit Suresh ◽  
H.P. Nandeesh ◽  
Deepak Suvarna ◽  
D. Chandrababu ◽  
H.R. Jeevan

2020 ◽  
Vol 13 (4) ◽  
pp. 251-254 ◽  
Author(s):  
Ibrahim N. Muhsen ◽  
Ali Alahmari ◽  
Mohammed Alnahedh ◽  
Nora A. Alkhudair ◽  
Hadeel Samarkandi ◽  
...  

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