Aurora Kinase Inhibitors: A New Class of Targeted Drugs in Cancer

2006 ◽  
Vol 8 (2) ◽  
pp. 93-98 ◽  
Author(s):  
Oliver Gautschi ◽  
Philip C. Mack ◽  
Angela M. Davies ◽  
Primo N. Lara ◽  
David R. Gandara
Keyword(s):  
Kinase Inhibitors ◽  
Aurora Kinase ◽  
Targeted Drugs ◽  
New Class ◽  
Aurora Kinase Inhibitors

Aurora kinase inhibitors: a new class of drugs targeting the regulatory mitotic system

2009 ◽  
Vol 11 (12) ◽  
pp. 787-798 ◽  
Author(s):  
José Alejandro Pérez Fidalgo ◽  
Desamparados Roda ◽  
Susana Roselló ◽  
Edith Rodríguez-Braun ◽  
Andrés Cervantes
Keyword(s):  
Kinase Inhibitors ◽  
Aurora Kinase ◽  
New Class ◽  
Aurora Kinase Inhibitors

scholarly journals Aurora kinase inhibitors: Potential molecular-targeted drugs for gynecologic malignant tumors

2013 ◽  
Vol 1 (3) ◽  
pp. 335-340 ◽  
Author(s):  
KIYOKO UMENE ◽  
KOUJI BANNO ◽  
IORI KISU ◽  
MEGUMI YANOKURA ◽  
YUYA NOGAMI ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Malignant Tumors ◽  
Aurora Kinase ◽  
Targeted Drugs ◽  
Aurora Kinase Inhibitors

Aurora Kinase Inhibitors in Head and Neck Cancer

2018 ◽  
Vol 18 (3) ◽  
pp. 199-213
Author(s):  
Guangying Qi ◽  
Jing Liu ◽  
Sisi Mi ◽  
Takaaki Tsunematsu ◽  
Shengjian Jin ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Therapy ◽  
Kinase Inhibitors ◽  
Biological Function ◽  
Aurora Kinase ◽  
Aurora Kinases ◽  
Related Research ◽  
Chemotherapy Drugs ◽  
Aurora Kinase Inhibitors

Aurora kinases are a group of serine/threonine kinases responsible for the regulation of mitosis. In recent years, with the increase in Aurora kinase-related research, the important role of Aurora kinases in tumorigenesis has been gradually recognized. Aurora kinases have been regarded as a new target for cancer therapy, resulting in the development of Aurora kinase inhibitors. The study and application of these small-molecule inhibitors, especially in combination with chemotherapy drugs, represent a new direction in cancer treatment. This paper reviews studies on Aurora kinases from recent years, including studies of their biological function, their relationship with tumor progression, and their inhibitors.

Discovery of novel 2,4-disubstituted pyrimidines as Aurora kinase inhibitors

2020 ◽  
Vol 30 (3) ◽  
pp. 126885 ◽  
Author(s):  
Yu Xu ◽  
Shu-Yi Hao ◽  
Xiu-Juan Zhang ◽  
Wen-Bo Li ◽  
Xue-Peng Qiao ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitors

Aurora Kinase Inhibitors

2007 ◽  
pp. 157-175
Author(s):  
Mitesh Borad ◽  
Steven Warner ◽  
Daniel Von Hoff
Keyword(s):  
Kinase Inhibitors ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitors

scholarly journals Update on Aurora Kinase Inhibitors in Gynecologic Malignancies

2008 ◽  
Vol 3 (3) ◽  
pp. 162-177 ◽  
Author(s):  
Xia Tao ◽  
Hye Chon ◽  
Siqing Fu ◽  
John Kavanagh ◽  
Wei Hu
Keyword(s):  
Kinase Inhibitors ◽  
Aurora Kinase ◽  
Gynecologic Malignancies ◽  
Aurora Kinase Inhibitors
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