Long-Term Treatment with Bevacizumab for Patients with Metastatic Colorectal Cancer: Case Report

2006 ◽  
Vol 6 (1) ◽  
pp. 66-69 ◽  
Author(s):  
Herbert I. Hurwitz ◽  
Wanda Honeycutt ◽  
Sherri Haley ◽  
Justin Favaro
Keyword(s):  
Colorectal Cancer ◽  
Case Report ◽  
Metastatic Colorectal Cancer ◽  
Term Treatment ◽  
Cancer Case ◽  
Long Term Treatment ◽  
Colorectal Cancer Case

Case-Report: Folfoxiri Plus Bevacizumab in “Poor-Risk” Liver-Only Metastatic Colorectal Cancer: Case Report and State-of-the-Art

2013 ◽  
Vol 1 (1) ◽  
pp. 78-83
Author(s):  
Lisa Salvatore ◽  
Fotios Loupakis ◽  
Andrea Ciarlo ◽  
Chiara Cremolini ◽  
Camilla Comin ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Case Report ◽  
Metastatic Colorectal Cancer ◽  
State Of The Art ◽  
Cancer Case ◽  
Poor Risk ◽  
Colorectal Cancer Case

INFLUENCE OF THE AGE FACTOR AND TUMOR IMMUNOPHENOTYPE ON THE EFFECTIVENESS OF CYTOREDUCTIVE OPERATIONS IN METASTATIC COLORECTAL CANCER

2019 ◽  
Vol 65 (6) ◽  
pp. 855-862
Author(s):  
Nikolay Maystrenko ◽  
Georgiy Manikhas ◽  
Aleksey Sazonov ◽  
Vadim Chirskiy ◽  
Alina Yerokhina
Keyword(s):  
Colorectal Cancer ◽  
Metastatic Colorectal Cancer ◽  
Significant Risk ◽  
Biological Properties ◽  
Term Treatment ◽  
Ki 67 ◽  
Immunohistochemical Markers ◽  
Long Term Treatment ◽  
Age Factor

Aim of the study. To analyze the effectiveness and safety of cytoreductive interventions in patients with IV stage colorectal cancer in account of the age factor and to assess the effect of the molecular biological properties of the tumor on long-term treatment results. Materials and methods. A comparative evaluation of the results of surgical treatment of metastatic colorectal cancer in patients of various age groups was carried out. The clinical significance of immunohistochemical markers for predicting long-term treatment outcomes has been studied. Results. The most significant risk factors for the development of postoperative complications were identified. The prognostic value of immunohistochemical markers such as the proliferative index of stem cancer cells (ALDH + Ki-67 +) and the chemokine receptor CXCR4 has been established. Conclusion. A comprehensive analysis of the molecular biological properties of the tumor, coupled with an assessment of the functional operability of patients, provides a personalized approach to the choice of surgical tactics in patients with stage IV colorectal cancer, which allows counting on the encouraging results of cytoreductive interventions.

scholarly journals Long-Term Treatment of Metastatic Colorectal Cancer with Panitumumab

2012 ◽  
Vol 6 ◽  
pp. CMO.S5055 ◽  
Author(s):  
Miriam López-Gómez ◽  
María Merino ◽  
Enrique Casado
Keyword(s):  
Colorectal Cancer ◽  
Monoclonal Antibody ◽  
Metastatic Colorectal Cancer ◽  
Systemic Chemotherapy ◽  
Term Treatment ◽  
Long Term Treatment

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. More than 30% patients present with metastases at diagnoses and will require systemic chemotherapy. In recent years many anti-EGFR targets have been developed. Among them, panitumumab, a fully human IgG2 monoclonal antibody has shown important benefits in the treatment of this disease.

scholarly journals Liver transplantation for metastatic colorectal cancer (case report)

2019 ◽  
Vol 23 (4) ◽  
pp. 54-67
Author(s):  
I. A. Porshennikov ◽  
A. V. Sokolov ◽  
E. E. Shchekina ◽  
A. Yu. Chubukov ◽  
T. A. Tretyakova ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Liver Transplantation ◽  
Metastatic Colorectal Cancer ◽  
Short Review ◽  
Cancer Case ◽  
Current State ◽  
Cancer Metastases ◽  
Colorectal Cancer Case ◽  
Unresectable Liver Metastases ◽  
Colorectal Cancer Metastases

Liver transplantation is currently controversial for colorectal cancer metastases and not recommended in clinical guidelines. We report the first Russian case of liver transplantation from cadaveric donor in a patient with multiple bilobar unresectable liver metastases of colon cancer. We observe no recurrences within 10 months on everolimus-based immunosuppression and adjuvant treatment. The current state of the problem and the place of liver transplantation in metastatic colorectal cancer treatment are discussed in a short review.

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